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National Guideline Centre (UK). Cirrhosis in Over 16s: Assessment and Management. London: National Institute for Health and Care Excellence (NICE); 2016 Jul. (NICE Guideline, No. 50.)
M.1. Risk factors and risk assessment tools
None.
M.2. Diagnostic tests
Table 48Studies excluded from the economic review
| Reference | Reason for exclusion |
|---|---|
| Crossan 2015177 | Population does not match protocol: diagnostic tests for cirrhosis were assessed for a population with mixed aetiology; protocol specifies testing of people with different aetiologies must be analysed separately. |
M.3. Severity risk tools
None.
M.4. Surveillance for the early detection of hepatocellular carcinoma (HCC)
Table 49Studies excluded from the economic review
| Reference | Reason for exclusion |
|---|---|
| Ruelas 2004639 | Population does not match protocol: study included people without cirrhosis. |
M.5. Surveillance for the detection of varices
None.
M.6. Prophylaxis of variceal haemorrhage
Table 50Studies excluded from the economic review
| Study | Exclusion reason |
|---|---|
| Dipascoli 2014204 | Intervention does not match protocol: beta-blocker used was nadolol. |
M.7. Primary prevention of bacterial infections in cirrhosis and upper gastrointestinal bleeding
None.
M.8. Transjugular intrahepatic portosystemic shunt (TIPS) versus large-volume paracentesis (LVP) for ascites
Table 51Studies excluded from the economic review
| Reference | Reason for exclusion |
|---|---|
| Parker 2013581 | This study was assessed as not applicable due to the study design: it compared costs of the same patients before and after TIPS was carried out; no randomisation. |
M.9. Primary prevention of spontaneous bacterial peritonitis (SBP) in people with cirrhosis and ascites
None.
M.10. Volume replacers in hepatorenal syndrome
None.
M.11. Management of an episode of acute hepatic encephalopathy
None.
- Risk factors and risk assessment tools
- Diagnostic tests
- Severity risk tools
- Surveillance for the early detection of hepatocellular carcinoma (HCC)
- Surveillance for the detection of varices
- Prophylaxis of variceal haemorrhage
- Primary prevention of bacterial infections in cirrhosis and upper gastrointestinal bleeding
- Transjugular intrahepatic portosystemic shunt (TIPS) versus large-volume paracentesis (LVP) for ascites
- Primary prevention of spontaneous bacterial peritonitis (SBP) in people with cirrhosis and ascites
- Volume replacers in hepatorenal syndrome
- Management of an episode of acute hepatic encephalopathy
- Excluded health economic studies - Cirrhosis in Over 16sExcluded health economic studies - Cirrhosis in Over 16s
- Diagnostic tests - Cirrhosis in Over 16sDiagnostic tests - Cirrhosis in Over 16s
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