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Omalizumab (Xolair): Treatment of Adults and Adolescents (12 Years of Age and above) with Chronic Idiopathic Urticaria [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Aug.

Cover of Omalizumab (Xolair)

Omalizumab (Xolair): Treatment of Adults and Adolescents (12 Years of Age and above) with Chronic Idiopathic Urticaria [Internet].

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Clinical Review Report

Drugomalizumab (Xolair) (150 mg and 300 mg subcutaneous injection)
IndicationTreatment of adults and adolescents (12 years of age and above) with chronic idiopathic urticaria who remain symptomatic despite H1 antihistamine treatment
Listing requestTreatment of adults and adolescents (12 years of age and above) with persistent (disease duration ≥ 6 months) moderate to severe (UAS7 score ≥ 16 or DLQI ≥ 10) chronic idiopathic urticaria who remain symptomatic (presence of hives and/or associated itching) despite H1-antihistamine treatment.
ManufacturerNovartis Pharmaceuticals Canada Inc.

ABBREVIATIONS

EXECUTIVE SUMMARY

1. INTRODUCTION

2. OBJECTIVES AND METHODS

3. RESULTS

4. DISCUSSION

5. CONCLUSIONS

APPENDIX 1 PATIENT INPUT SUMMARY

APPENDIX 2 LITERATURE SEARCH STRATEGY

APPENDIX 3 EXCLUDED STUDIES

APPENDIX 4 DETAILED OUTCOME DATA

APPENDIX 5 VALIDITY OF OUTCOME MEASURES

REFERENCES

Copyright © CADTH 2015.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK362690

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