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Glycerol Phenylbutyrate (Ravicti) [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Apr.

Cover of Glycerol Phenylbutyrate (Ravicti)

Glycerol Phenylbutyrate (Ravicti) [Internet].

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ABBREVIATIONS

AE

adverse event

ANOVA

analysis of variance

ASS

argininosuccinate synthetase

BRIEF

Behavior Rating Inventory of Executive Function

CBCL

Child Behavior Checklist

CI

confidence interval

CORD

Canadian Organization for Rare Disorders

CPS1

carbamoyl phosphate synthetase 1

CVLT-II

California Verbal Learning Test

DB

Double blind

GI

gastrointestinal

GPB

glycerol phenylbutyrate

HAC

hyperammonemic crises

HC

Health Canada

HRQoL

health-related quality of life

ITT

intention-to-treat

IQ

intelligence quotient

NaPBA

sodium phenylbutyrate

OTC

ornithine transcarbamylase

PedsQL SF15

Pediatric Quality of Life Inventory Generic Core Scales SF15 (short form 15)

PP

per-protocol

QoL

quality of life

RCT

randomized controlled trial

SAE

serious adverse event

SD

standard deviation

SF-36

Short Form (36) Health Survey

TNAUC

time-normalized area under the curve

UCD

urea cycle disorder

ULN

upper limit of normal

WASI-II

Wechsler Abbreviated Scale of Intelligence

WPPSI-III

Wechsler Preschool and Primary Scale of Intelligence

Copyright © CADTH 2017.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK476297

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