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Edoxaban (Lixiana) [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Apr.
| OVERVIEW | |
|---|---|
| Interface: | Ovid |
| Databases: | Embase 1974 to present |
| MEDLINE Daily and MEDLINE 1946 to present | |
| MEDLINE In-Process & Other Non-Indexed Citations | |
| Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid. | |
| Date of Search: | October 7, 2016 |
| Alerts: | Weekly search updates until February 15, 2016 |
| Study Types: | No search filters were applied |
| Limits: | No language or date limits |
| Human only | |
| Conference abstracts were excluded | |
| SYNTAX GUIDE | |
| / | At the end of a phrase, searches the phrase as a subject heading |
| .sh | At the end of a phrase, searches the phrase as a subject heading |
| MeSH | Medical Subject Heading |
| fs | Floating subheading |
| exp | Explode a subject heading |
| * | Before a word, indicates that the marked subject heading is a primary topic; or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings |
| # | Truncation symbol for one character |
| ? | Truncation symbol for one or no characters only |
| adj | Requires words are adjacent to each other (in any order) |
| adj# | Adjacency within # number of words (in any order) |
| .ti | Title |
| .ab | Abstract |
| .ot | Original title |
| .hw | Heading word; usually includes subject headings and controlled vocabulary |
| .pt | Publication type |
| .rn | CAS registry number |
| .nm | Name of substance word |
| pmez | Ovid database code; MEDLINE In-Process & Other Non-Indexed Citations, MEDLINE Daily and Ovid MEDLINE 1946 to Present |
| oemezd | Ovid database code; Embase 1974 to present, updated daily |
| MULTI-DATABASE STRATEGY | |
|---|---|
| # | Searches |
| 1 | (Edoxaban* or Lixiana* or Savaysa* or DU 176* or DU176* or 32W99UE810 or UNII32W99UE810 or 606P02282F or UNII606P02282F or NDU3J18APO or UNIINDU3J18APO or 972203R4EW or UNII972203R4EW).ti,ab,kf,kw,ot,hw,rn,nm. |
| 2 | (480448 29 1 or “480448291” or 48044829 1 or 48044829 1 or “0480448291” or 480449 70 5 or 48044970 5 or “480449705” or 480449 705 or 480449 71 6 or “480449716” or 48044971 6 or 480449 716 or 1229194 11 9 or “1229194119” or “122919411 9” or 1229194 119).rn,nm. |
| 3 | 1 or 2 |
| 4 | 3 use ppez |
| 5 | exp *edoxaban/ |
| 6 | (Edoxaban* or Lixiana* or Savaysa* or DU 176* or DU176*).ti,ab,kw. |
| 7 | 5 or 6 |
| 8 | 7 use oemezd |
| 9 | 4 or 8 |
| 10 | exp animals/ |
| 11 | exp animal experimentation/ or exp animal experiment/ |
| 12 | exp models animal/ |
| 13 | nonhuman/ |
| 14 | exp vertebrate/ or exp vertebrates/ |
| 15 | animal.po. |
| 16 | or/10–15 |
| 17 | exp humans/ |
| 18 | exp human experimentation/ or exp human experiment/ |
| 19 | human.po. |
| 20 | or/17–19 |
| 21 | 16 not 20 |
| 22 | 9 not 21 |
| 23 | 22 not conference abstract.pt. |
| 24 | remove duplicates from 23 |
| OTHER DATABASES | |
|---|---|
| PubMed | Same MeSH, keywords, limits, and study types used as per MEDLINE search, with appropriate syntax used. |
| Trial registries (Clinicaltrials.gov and others) | Same keywords, limits used as per MEDLINE search. |
| Dates for Search: | October 10, 2016. |
| Keywords: | Drug name, Indication |
| Limits: | No language or date limits used |
Relevant websites from the following sections of the CADTH grey literature checklist, “Grey matters: a practical tool for evidence-based searching” (http://www.cadth.ca/en/resources/finding-evidence-is/grey-matters) were searched:
Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/
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