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Ustekinumab (Stelara) [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Apr.
Reference | Reason for Exclusion |
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Sandborn W, Gasink C, Blank M, Lang Y, Johanns J, Gao LL, et al. A multicenter, double-blind, placebo-controlled phase3 study of ustekinumab, a human IL-12/23P40 mAB, in moderate-service Crohn’s disease refractory to anti-TFN alpha: UNITI-1. Inflamm Bowel Dis. 2016 Mar;22(suppl 1):s1-O-001. | Abstract for UNITI-1 |
Sandborn WJ, Feagan BG, Fedorak RN, Scherl E, Fleisher MR, Katz S, et al. A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn’s disease. Gastroenterology. 2008 Oct;135(4):1130–41. | Treatment regimens not Health Canada–approved |
- EXCLUDED STUDIES - Ustekinumab (Stelara)EXCLUDED STUDIES - Ustekinumab (Stelara)
- PATIENT INPUT - Glycerol Phenylbutyrate (Ravicti)PATIENT INPUT - Glycerol Phenylbutyrate (Ravicti)
- INTERPRETATIONS AND KEY LIMITATIONS - Somatropin (Genotropin) (0.15 mg/day to 0....INTERPRETATIONS AND KEY LIMITATIONS - Somatropin (Genotropin) (0.15 mg/day to 0.3 mg/day)
- CONCLUSIONS - Ustekinumab (Stelara)CONCLUSIONS - Ustekinumab (Stelara)
- SUMMARY OF THE MANUFACTURER’S PE SUBMISSION - Glycerol Phenylbutyrate (Ravicti)SUMMARY OF THE MANUFACTURER’S PE SUBMISSION - Glycerol Phenylbutyrate (Ravicti)
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