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Clinical Review Report: Doravirine (Pifeltro): (Merck Canada Inc.): Indication: Doravirine (Pifeltro) is indicated, in combination with other antiretroviral medicinal products, for the treatment of adults infected with HIV-1 without past or present evidence of viral resistance to doravirine [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Jun.

Cover of Clinical Review Report: Doravirine (Pifeltro)

Clinical Review Report: Doravirine (Pifeltro): (Merck Canada Inc.): Indication: Doravirine (Pifeltro) is indicated, in combination with other antiretroviral medicinal products, for the treatment of adults infected with HIV-1 without past or present evidence of viral resistance to doravirine [Internet].

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Appendix 2Literature Search Strategy

OVERVIEW
Interface:Ovid
Databases:

MEDLINE All (1946–)

Embase (1974–)

Note: Subject headings have been customized for each database. Duplicates between databases were removed in Ovid.

Date of search:December 12, 2018
Alerts:Weekly search updates until project completion
Study types:No search filters were applied
Limits:

Publication date limit: none

Language limit: none

Conference abstracts: excluded

SYNTAX GUIDE
/At the end of a phrase, searches the phrase as a subject heading
MeSHMedical Subject Heading
expExplode a subject heading
*

Before a word, indicates that the marked subject heading is a primary topic;

or, after a word, a truncation symbol (wildcard) to retrieve plurals or varying endings

.tiTitle
.abAbstract

.ot

.hw

Original title

Heading word; usually includes subject headings and controlled vocabulary

.kfAuthor keyword heading word (MEDLINE)
.kwAuthor keyword (Embase)
.ptPublication type

.rn

.nm

Registry number

Name of substance word

.dqCandidate Term Word (Embase)
medallOvid database code: MEDLINE All, 1946 to present, updated daily
oemezdOvid database code; Embase, 1974 to present, updated daily
MULTI-DATABASE STRATEGY
1(pifeltro* or doravirine* or delstrigo* or MK-1439* or MK1439* or 913P6LK81M).ti,ab,ot,kf,hw,rn,nm.
21 use medall
3*doravirine/ or (pifeltro* or doravirine* or delstrigo* or MK-1439* or MK1439*).ti,ab,kw,dq.
43 use oemezd
54 not (conference review or conference abstract).pt.
62 or 5
7remove duplicates from 6
CLINICAL TRIAL REGISTRIES
ClinicalTrials​.gov

Produced by the US National Library of Medicine. Targeted search used to capture registered clinical trials.

[Search terms: pifeltro, doravirine, delstrigo, MK-1439, MK1439]

WHO ICTRP

International Clinical Trials Registry Platform, produced by the World Health Organization. Targeted search used to capture registered clinical trials.

[Search terms: pifeltro, doravirine, delstrigo, MK-1439, MK1439]

OTHER DATABASES
PubMedSearched to capture records not found in MEDLINE. Same MeSH, keywords, limits, and study types used as per MEDLINE search, with appropriate syntax used.

Grey Literature

Dates for Search:December 2018
Keywords:Pifeltro (doravirine), HIV-1
Limits:none

Relevant websites from the following sections of the CADTH grey literature checklist Grey Matters: a practical tool for searching health-related grey literature (https://www.cadth.ca/grey-matters) were searched:

  • Health Technology Assessment Agencies
  • Health Economics
  • Clinical Practice Guidelines
  • Drug and Device Regulatory Approvals
  • Advisories and Warnings
  • Drug Class Reviews
  • Clinical Trial Registries
  • Databases (free)
  • Internet Search

Copyright © 2019 Canadian Agency for Drugs and Technologies in Health.

The copyright and other intellectual property rights in this document are owned by CADTH and its licensors. These rights are protected by the Canadian Copyright Act and other national and international laws and agreements. Users are permitted to make copies of this document for non-commercial purposes only, provided it is not modified when reproduced and appropriate credit is given to CADTH and its licensors.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK544869
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