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Thangaratinam S, Rogozińska E, Jolly K, et al. Interventions to Reduce or Prevent Obesity in Pregnant Women: A Systematic Review. Southampton (UK): NIHR Journals Library; 2012 Jul. (Health Technology Assessment, No. 16.31.)
Interventions to Reduce or Prevent Obesity in Pregnant Women: A Systematic Review.
Show details| Quality assessment | Summary of findings | Importance | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of patients | Effect | Quality | |||||||||
| No. of studies | Design | Limitations | Inconsistency | Indirectness | Imprecision | Other considerations | Physical activity | Control | OR/RR (95% CI) | ||
| Cord abnormalities | |||||||||||
| 3 | Observational studies | Very seriousa | No serious inconsistency | No serious indirectness | No serious imprecision | None | 9/238 (3.8%)b | 18/217 (8.3%) | OR 0.43 (0.19 to 0.99) | ⊕⊖⊖⊖ Very low | Important |
| Stimulation for abnormal labour pattern | |||||||||||
| 1 | Observational studies | Very seriousa | No serious inconsistency | No serious indirectness | Very seriousc | None | 11/87 (12.6%) | 9/44 (20.5%) | RR 0.56 (0.21 to 1.48) | ⊕⊖⊖⊖ Very low | N/A |
| Meconium-stained liquor | |||||||||||
| 1 | Randomised trials | No serious limitationsd,e,f | No serious inconsistency | No serious indirectness | Very seriousc | None | 4/38 (10.5%) | 8/47 (17.0%) | RR 0.62 (0.2 to 1.9) | ⊕⊕⊖⊖ Low | N/A |
| Abnormal fetal heart rate | |||||||||||
| 1 | Observational studies | Very seriousa | No serious inconsistency | No serious indirectness | Very seriousc | None | 12/87 (13.8%) | 11/44 (25.0%) | OR 0.48 (0.19 to 1.2) | ⊕⊖⊖⊖ Very low | N/A |
| Nuchal cord | |||||||||||
| 1 | Observational studies | Very seriousa | No serious inconsistency | No serious indirectness | No serious imprecision | None | 23/87 (26.4%) | 24/44 (54.5%) | OR 0.3 (0.14 to 0.64) | ⊕⊖⊖⊖ Very low | N/A |
| Threatened abortion | |||||||||||
| 1 | Observational studies | Very seriousg | No serious inconsistency | No serious indirectness | Very seriousc | None | 1/21 (4.8%) | 1/11 (9.1%) | OR 0.5 (0.03 to 8.85) | ⊕⊖⊖⊖ Very low | Important |
| Failure to progress with oxytocin augmentation: mother | |||||||||||
| 1 | Observational studies | Very seriousg | No serious inconsistency | No serious indirectness | Very seriousc | None | 3/21 (14.3%) | 3/11 (27.3%) | OR 0.44 (0.07 to 2.7) | ⊕⊖⊖⊖ Very low | N/A |
| Chorioamnionitis | |||||||||||
| 1 | Randomised trials | No serious limitations | No serious inconsistency | No serious indirectness | Serious imprecision | None | 1/38 (2.6%) | 0/47 (0%) | OR 3.69 (0.15 to 88.13) | ⊕⊕⊕⊕ Low | Important |
| Maternal anaemia | |||||||||||
| 1 | Observational studies | Very seriousg | No serious inconsistency | No serious indirectness | Very seriousc | None | 3/21 (14.3%) | 2/11 (18.2%) | OR 0.75 (0.11 to 5.3) | ⊕⊖⊖⊖ Very low | Important |
| Maternal sepsis | |||||||||||
| 1 | Observational studies | Very seriousg | No serious inconsistency | No serious indirectness | Very seriousc | None | 0/21 (0%) | 1/11 (9.1%) | OR 0.16 (0.01 to 4.35) | ⊕⊖⊖⊖ Very low | N/A |
| Uterine atony | |||||||||||
| 1 | Randomised trials | No serious limitationsd,e,f | No serious inconsistency | No serious indirectness | Serious imprecision | None | 3/38 (7.9%) | 4/47 (8.5%) | RR 0.93 (0.22 to 3.89) | ⊕⊕⊕⊕ Low | N/A |
N/A, not available.
- a
Observational study, 6 points (9 max.) in NOS questionnaire.
- b
Exercise (heavy).
- c
Wide CI.
- d
Poor information about allocation concealment, which was assessed as not strongly significant.
- e
Poor information about blinding of subjective outcomes, which was assessed as not strongly significant.
- f
Poor information about adequate sequence generation, which was assessed as not strongly significant.
- g
Observational study, 4 points (9 maximum) in NOS questionnaire.
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