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Lenney W, McKay AJ, Tudur Smith C, et al.; MASCOT Study Group. Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety. Southampton (UK): NIHR Journals Library; 2013 Feb. (Health Technology Assessment, No. 17.4.)
Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety.
Show detailsThe MASCOT TMG are very grateful to all of the principal investigators, research practitioners, site pharmacists, GPs, children and their carers and families for their contribution, commitment and enthusiasm. The MASCOT TMG is also grateful to the following: GlaxoSmithKline plc for the manufacture of the Flixotide Accuhaler and the Seretide Accuhaler and Merck Sharp and Dohme Ltd for the manufacture of Singulair (montelukast) and the matching placebo; the Local Research Networks in England; Sophie Perry and Heather Granville, MASCOT trial co-ordinators; Casey Quinn and Lisa Webster, health economic analysis support; Sadie Clayton, respiratory nurse; the Trial Steering Committee (chaired by Dr Anne Thomson) and the Data Monitoring and Ethics Committee (chaired by Dr David Spencer) for their support and work throughout the study; Mr and Mrs Hilton for their invaluable contributions; and the Guy Hilton Asthma Trust for financial support to produce and distribute hand-held records for patients.
The MASCOT research team acknowledges the support of the NIHR through the MRCN. It also acknowledges the funding supplied from the HTA programme.
Contribution of authors
Warren Lenney was the chief investigator, liaised with all the of the clinical centres involved, worked closely with the trial co-ordinators and headed up the team that drew up the interim and final reports.
David Price was a member of the TMG and contributed to the design and conduct of the study, provided expertise in primary care and prepared the report for publication.
Andrew McKay (Trial Statistician) was a member of the TMG, performed the statistical analyses and report preparation during the study and prepared the report for publication.
Catrin Tudur Smith (Senior Lecturer in Biostatistics) was a member of the TMG, led the statistical team, contributed to the design of the study, its conduct and analysis and prepared the report for publication.
Paula Williamson (Director of the CTU and Professor of Medical Statistics) was a member of the TMG, contributed to the design and conduct of the study and reviewed a draft of the report.
Marilyn James (Professor of the Economics of Health and Social Policy) led the health economics team and contributed to the design and analysis of the study and prepared the report for publication.
Name | Role | Hospital |
---|---|---|
Dr. Andrew Collinson | Principal investigator | Royal and Exeter, NHS Foundation Trust |
Dr Patrick Oades | Principal investigator | |
Michelle Curtis | Research nurse | |
Celia Charlton | Research nurse | |
Tania Crabb | South West PCRN | |
Dr David Lacy | Principal investigator | Arrowe Park Hospital, Wirral |
Lucy Meredith | Research nurse | |
Becky Bryson | Paediatric respiratory nurse | |
Dr Hitesh Pandya | Principal investigator | Leicester Royal Infirmary |
Samantha Hunt | Research nurse | |
Dr Chris Upton | Principal investigator | Norfolk and Norwich University Hospitals |
Alison Betteridge | Research nurse | |
Dr Tom Hilliard | Principal investigator | Bristol Royal Hospital for Children |
Myriam Kanchanatheera | Research nurse | |
Dr Caroline Pao | Principal investigator | Royal London Hospital |
Pauleen Waithe | Research nurse | |
Gemma Barry | Research nurse | |
Frances Ling | Research nurse | |
Shelley Mieres | Research nurse | |
Dr Will Carroll | Principal investigator | Derbyshire Children's Hospital |
Vanessa Unsworth | Research nurse | |
Coral Smith | Research nurse | |
Samantha Jones | Research nurse | |
Professor Harish Vyas | Principal investigator | University Hospital Nottingham |
Caroline Youle | Research nurse | |
Dr Jon Couriel | Principal investigator | Alder Hey Children's NHS Foundation Trust |
Gillian Webster | Research nurse | |
Janet Hall | Research nurse | |
Carol Stanton | North West PCRN | |
Dr Clare Murray | Principal investigator | Royal Manchester Children's Hospital |
Helena Prady | Research nurse | |
Claire Fish | Research nurse | |
Dr Stephen Turner | Principal investigator | Royal Aberdeen Children's Hospital |
Richard Leece | Research nurse | |
Lindsay Cameron | Research nurse | |
Amanda Cardy | Scottish PCRN | |
Dr Edward Simmonds | Principal investigator | University Hospitals Coventry and Warwickshire NHS Trust |
Karen Miles | Research nurse | |
Pauline Derbyshire | West Midlands PCRN | |
Professor Warren Lenney | Principal investigator | University Hospital of North Staffordshire |
Hilary Shepley | Research nurse | |
Katharine Beamond | Research nurse | |
Margo Brady | Research nurse | |
Marie Phipps | Research nurse | |
Dr Mark Porcheret | GP |
Disclaimers
This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, NETSCC, the HTA programme or the Department of Health.
Publications
- Lenney W, Perry S, Price D. Clinical trials and tribulations: the MASCOT study. Thorax 2011;66:457–8.
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