U.S. flag

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Lenney W, McKay AJ, Tudur Smith C, et al.; MASCOT Study Group. Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety. Southampton (UK): NIHR Journals Library; 2013 Feb. (Health Technology Assessment, No. 17.4.)

Cover of Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety

Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety.

Show details

Acknowledgements

The MASCOT TMG are very grateful to all of the principal investigators, research practitioners, site pharmacists, GPs, children and their carers and families for their contribution, commitment and enthusiasm. The MASCOT TMG is also grateful to the following: GlaxoSmithKline plc for the manufacture of the Flixotide Accuhaler and the Seretide Accuhaler and Merck Sharp and Dohme Ltd for the manufacture of Singulair (montelukast) and the matching placebo; the Local Research Networks in England; Sophie Perry and Heather Granville, MASCOT trial co-ordinators; Casey Quinn and Lisa Webster, health economic analysis support; Sadie Clayton, respiratory nurse; the Trial Steering Committee (chaired by Dr Anne Thomson) and the Data Monitoring and Ethics Committee (chaired by Dr David Spencer) for their support and work throughout the study; Mr and Mrs Hilton for their invaluable contributions; and the Guy Hilton Asthma Trust for financial support to produce and distribute hand-held records for patients.

The MASCOT research team acknowledges the support of the NIHR through the MRCN. It also acknowledges the funding supplied from the HTA programme.

Contribution of authors

Warren Lenney was the chief investigator, liaised with all the of the clinical centres involved, worked closely with the trial co-ordinators and headed up the team that drew up the interim and final reports.

David Price was a member of the TMG and contributed to the design and conduct of the study, provided expertise in primary care and prepared the report for publication.

Andrew McKay (Trial Statistician) was a member of the TMG, performed the statistical analyses and report preparation during the study and prepared the report for publication.

Catrin Tudur Smith (Senior Lecturer in Biostatistics) was a member of the TMG, led the statistical team, contributed to the design of the study, its conduct and analysis and prepared the report for publication.

Paula Williamson (Director of the CTU and Professor of Medical Statistics) was a member of the TMG, contributed to the design and conduct of the study and reviewed a draft of the report.

Marilyn James (Professor of the Economics of Health and Social Policy) led the health economics team and contributed to the design and analysis of the study and prepared the report for publication.

The MASCOT study group

NameRoleHospital
Dr. Andrew CollinsonPrincipal investigatorRoyal and Exeter, NHS Foundation Trust
Dr Patrick OadesPrincipal investigator
Michelle CurtisResearch nurse
Celia CharltonResearch nurse
Tania CrabbSouth West PCRN
Dr David LacyPrincipal investigatorArrowe Park Hospital, Wirral
Lucy MeredithResearch nurse
Becky BrysonPaediatric respiratory nurse
Dr Hitesh PandyaPrincipal investigatorLeicester Royal Infirmary
Samantha HuntResearch nurse
Dr Chris UptonPrincipal investigatorNorfolk and Norwich University Hospitals
Alison BetteridgeResearch nurse
Dr Tom HilliardPrincipal investigatorBristol Royal Hospital for Children
Myriam KanchanatheeraResearch nurse
Dr Caroline PaoPrincipal investigatorRoyal London Hospital
Pauleen WaitheResearch nurse
Gemma BarryResearch nurse
Frances LingResearch nurse
Shelley MieresResearch nurse
Dr Will CarrollPrincipal investigatorDerbyshire Children's Hospital
Vanessa UnsworthResearch nurse
Coral SmithResearch nurse
Samantha JonesResearch nurse
Professor Harish VyasPrincipal investigatorUniversity Hospital Nottingham
Caroline YouleResearch nurse
Dr Jon CourielPrincipal investigatorAlder Hey Children's NHS Foundation Trust
Gillian WebsterResearch nurse
Janet HallResearch nurse
Carol StantonNorth West PCRN
Dr Clare MurrayPrincipal investigatorRoyal Manchester Children's Hospital
Helena PradyResearch nurse
Claire FishResearch nurse
Dr Stephen TurnerPrincipal investigatorRoyal Aberdeen Children's Hospital
Richard LeeceResearch nurse
Lindsay CameronResearch nurse
Amanda CardyScottish PCRN
Dr Edward SimmondsPrincipal investigatorUniversity Hospitals Coventry and Warwickshire NHS Trust
Karen MilesResearch nurse
Pauline DerbyshireWest Midlands PCRN
Professor Warren LenneyPrincipal investigatorUniversity Hospital of North Staffordshire
Hilary ShepleyResearch nurse
Katharine BeamondResearch nurse
Margo BradyResearch nurse
Marie PhippsResearch nurse
Dr Mark PorcheretGP

Disclaimers

This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, NETSCC, the HTA programme or the Department of Health.

Publications

  1. Lenney W, Perry S, Price D. Clinical trials and tribulations: the MASCOT study. Thorax 2011;66:457–8.
Copyright © Queen's Printer and Controller of HMSO 2013. This work was produced by Lenney et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK260305

Views

  • PubReader
  • Print View
  • Cite this Page
  • PDF version of this title (2.4M)

Other titles in this collection

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...