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Boonacker CWB, Rovers MM, Browning GG, et al. Adenoidectomy with or without grommets for children with otitis media: an individual patient data meta-analysis. Southampton (UK): NIHR Journals Library; 2014 Jan. (Health Technology Assessment, No. 18.5.)

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Adenoidectomy with or without grommets for children with otitis media: an individual patient data meta-analysis.

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Appendix 10Number and percentage of children failing according to each component of the composite end point

Recurrent AOM, n/N (%)Persistent OME, n/N (%)Improvement in hearing level < 10 dB, n/N (%)Additional surgery, n/N (%)Composite end point, n/N (%)
Adenoidectomy with unilateral or bilateral grommets
Black 199052–39/75 (52.0)–1/75 (1.3)40/75 (53.3)
Casselbrant 2009110/31 (0.0)0/24 (0.0)–1/32 (3.1)1/32 (3.1)
Dempster 199312–24/37 (64.9)7/37 (18.9)NA25/37 (67.6)
Hammarén-Malmi 200515,5117/102 (16.7)––10/110 (9.1)22/110 (20.0)
Kujala 2012174/101 (4.0)0/40 (0.0)–6/101 (5.9)9/101 (8.9)
Mattila 2003184/45 (8.9)––0/73 (0.0)4/73 (5.5)
Maw 1986,19 199310–52/83 (62.7)18/49 (36.7)7/80 (8.8)56/83 (67.5)
MRC Multicentre Otitis Media Study Group 20122010/117 (8.5)38/114 (33.3)30/111 (27.0)2/128 (1.6)61/128 (47.7)
Nguyen 2004210/17 (0.0)0/13 (0.0)–0/33 (0.0)0/33 (0.0)
Adenoidectomy alone
Casselbrant 2009111/35 (2.9)0/29 (0.0)–6/35 (17.1)7/35 (20.0)
Koivunen 20041616/60 (26.7)0/60 (0.0)–5/60 (8.3)20/60 (33.3)
Unilateral or bilateral grommets
Black 199052–39/74 (52.7)–7/77 (9.1)44/77 (57.1)
Casselbrant 2009110/31 (0.0)0/27 (0.0)–3/31 (9.7)3/31 (9.7)
Dempster 199312–21/35 (60.0)11/35 (31.4)NA22/35 (62.9)
Hammarén-Malmi 200515,517/96 (7.3)––13/107 (12.1)17/107 (15.9)
Kujala 2012179/98 (9.2)0/48 (0.0)–13/98 (13.3)17/98 (17.3)
Mattila 2003183/32 (9.4)––5/57 (8.8)5/57 (8.8)
Maw 1986,19 199310–67/83 (80.7)28/56 (50.0)31/83 (37.3)72/83 (86.7)
MRC Multicentre Otitis Media Study Group 20122015/119 (12.6)44/113 (38.9)47/110 (42.7)4/126 (3.2)71/126 (56.3)
Nguyen 2004210/28 (0.0)0/19 (0.0)–0/37 (0.0)0/37 (0.0)
Non-surgical
Koivunen 20041641/120 (34.2)0/120 (0.0)–30/120 (25.0)54/120 (45.0)
Kujala 20121717/101 (16.8)0/21 (0.0)–23/101 (22.8)30/101 (29.7)
MRC Multicentre Otitis Media Study Group 20122019/112 (17.0)83/112 (74.1)40/100 (40.0)43/122 (35.2)109/122 (89.3)

NA, surgery not allowed during follow-up.

Copyright © Queen’s Printer and Controller of HMSO 2014. This work was produced by Boonacker et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

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Bookshelf ID: NBK261522
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