List of abbreviations

The FolATED trialists namely (in alphabetical order); Emma Bedson; Diana Bell; Daniel Carr; Ben Carter; Dyfrig Hughes; Andrea Jorgensen; Helen Lewis; Keith Lloyd; Andrew McCaddon; Stuart Moat; Joshua Pink; Munir Pirmohamed; Seren Roberts; Ian Russell; Yvonne Sylvestre; Richard Tranter; Rhiannon Whitaker; Clare Wilkinson; Nefyn Williams

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Bedson E, Bell D, Carr D, et al.; The FolATED trialists namely (in alphabetical order). Folate Augmentation of Treatment – Evaluation for Depression (FolATED): randomised trial and economic evaluation. Southampton (UK): NIHR Journals Library; 2014 Jul. (Health Technology Assessment, No. 18.48.)

Folate Augmentation of Treatment – Evaluation for Depression (FolATED): randomised trial and economic evaluation.

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List of abbreviations

5-HT: 5-hydroxytryptamine
5-MTHF: 5-methyltetrahydrofolate
ADM: antidepressant medication
AE: adverse event
AHEAD: Assessing Health Economics of Anti-Depressants trial
AR: adverse reaction
AUC: area under the curve
BDI-II: Beck Depression Inventory (version 2)
BMI: body mass index
BNF: British National Formulary
bp: base pair
CGI: Clinical Global Impression
CI: confidence interval
CMHT: Community Mental Health Team
CNS: central nervous system
CRF: Case Report Form
CSF: cerebrospinal fluid
CTA: Clinical Trial Authorisation
CV: coefficient of variation
DMEC: Data Monitoring and Ethics Committee
EQ-5D: European Quality of life scale – 5 Dimensions
EQ-VAS: EQ-5D Visual Analogue Scale
FDR: false discovery rate
FolATED: Folate Augmentation of Treatment – Evaluation for Depression
GCP: Good Clinical Practice
GP: general medical practitioner
HADS: Hospital Anxiety and Depression Scale
HDRS: Hamilton Depression Rating Scale
HTA: Health Technology Assessment
ICD-10: International Statistical Classification of Diseases & Related Health Problems (10th Revision)
ICER: incremental cost-effectiveness ratio
IQR: interquartile range
MADRS: Montgomery–Åsberg Depression Rating Scale
MCAR: missing completely at random
MCS: Mental Component Score
MHRA: Medicines and Healthcare products Regulatory Agency
MHRN-Cymru: Mental Health Research Network for Wales
MINI: Mini International Neuropsychiatric Interview
MMA: methylmalonic acid
MRC: Medical Research Council
MREC: Multicentre Research Ethics Committee
MTHFR: methylenetetrahydrofolate reductase
MTR: methyltetrahydrofolate reductase
NICE: National Institute for Health and Care Excellence
NIHR: National Institute of Health Research
NISCHR: National Institute for Social Care and Health Research (Wales)
NISCHR CRC: NISCHR Clinical Research Centre
NWORTH: North Wales Organisation for Randomised Trials in Health
OLS: ordinary least squares
OR: odds ratio
PCS: physical component score
PHQ9: Patient Health Questionnaire – 9 items
PSS: Personal Social Services
QALY: quality-adjusted life-year
QOF: Quality & Outcomes Framework
RCF: red cell folate
RCT: randomised controlled trial
SAE: serious adverse event
SAR: serious adverse reaction
SD: standard deviation
SF-6D: UK Short Form Health Survey – 6 Dimensions
SF-12: UK 12-item Short Form Health Survey
SNP: single nucleotide polymorphism
SNRI: selective noradrenaline reuptake inhibitor
SOP: standard operating procedure
SSRI: selective serotonin reuptake inhibitor
SUSAR: suspected unexpected serious adverse reaction
TCA: tricyclic antidepressant
TSC: Trial Steering Committee
WHO: World Health Organization
WONCA: World Organization of National Colleges & Associations of Family Doctors

Copyright © Queen’s Printer and Controller of HMSO 2014. This work was produced by Bedson et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK262308

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Bedson E, Bell D, Carr D, et al.; The FolATED trialists namely (in alphabetical order). Folate Augmentation of Treatment – Evaluation for Depression (FolATED): randomised trial and economic evaluation. Southampton (UK): NIHR Journals Library; 2014 Jul. (Health Technology Assessment, No. 18.48.) List of abbreviations.
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List of abbreviations

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