- Plain English summary
- Scientific summary
- Chapter 1. Introduction and background
- Chapter 2. Methods for the systematic review of effectiveness
- Chapter 3. Clinical effectiveness: overview of included studies
- Chapter 4. Clinical effectiveness: ginger
- Chapter 5. Clinical effectiveness: acupressure, acupuncture and nerve stimulation
- Chapter 6. Clinical effectiveness: aromatherapy
- Chapter 7. Clinical effectiveness: vitamin B6 (pyridoxine)
- Chapter 8. Clinical effectiveness: pyridoxine/doxylamine combination
- Chapter 9. Clinical effectiveness: antihistamines
- Chapter 10. Clinical effectiveness: dopamine antagonists
- Chapter 11. Clinical effectiveness: serotonin antagonists (ondansetron)
- Chapter 12. Clinical effectiveness: intravenous fluids
- Chapter 13. Clinical effectiveness: transdermal clonidine
- Chapter 14. Clinical effectiveness: outpatient/day case management
- Chapter 15. Clinical effectiveness: corticosteroids
- Chapter 16. Clinical effectiveness: nasogastric enteral/jejunostomy feeding
- Chapter 17. Clinical effectiveness: gabapentin
- Chapter 18. Economic analysis
- Chapter 19. Issues of importance to patients
- Chapter 20. Issues of importance to practitioners
- Chapter 21. Discussion
- Chapter 22. Conclusions
- Acknowledgements
- References
- Appendix 1 Examples of hyperemesis gravidarum/nausea and vomiting in pregnancy assessment tools
- Appendix 2 Data abstraction form: clinical effectiveness
- Appendix 3 Risk of bias for randomised controlled trials
- Appendix 4 Quality of case series studies
- Appendix 5 Included papers
- Appendix 6 Excluded papers and reasons for exclusion
- Appendix 7 UK Teratology Information Service enquiries and follow-ups relating to hyperemesis gravidarum/nausea and vomiting in pregnancy medication
- Appendix 8 Secondary outcome data
- Appendix 9 Systematic review of published economic evaluations: inclusion criteria
- Appendix 10 Cost of drug interventions and recommended daily doses
- List of abbreviations