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Peters MJ, Khan I, Woolfall K, et al. Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT. Southampton (UK): NIHR Journals Library; 2019 Feb. (Health Technology Assessment, No. 23.5.)

Cover of Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT

Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT.

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List of abbreviations

AE

adverse event

CI

confidence interval

CONSORT

Consolidated Standards of Reporting Trials

CRF

case report form

CRN

Clinical Research Network

CTU

clinical trials unit

DMEC

Data Monitoring and Ethics Committee

eCRF

electronic case report form

FiSh

Fluids in Shock

GCP

good clinical practice

HRA

Health Research Authority

ICNARC

Intensive Care National Audit and Research Centre

IQR

interquartile range

NICE

National Institute for Health and Care Excellence

NIHR

National Institute for Health Research

NSAID

non-steroidal anti-inflammatory drug

PI

principal investigator

PICANet

Paediatric Intensive Care Audit Network

PICOS

Paediatric Intensive Care Outcome Study

PICU

paediatric intensive care unit

PIM2r

Paediatric Index of Mortality version 2r

PIM3

Paediatric Index of Mortality version 3

RCT

randomised controlled trial

RWPC

research without prior consent

SAE

serious adverse event

SD

standard deviation

SMG

Study Management Group

TSC

Trial Steering Committee

Copyright © Queen’s Printer and Controller of HMSO 2019. This work was produced by Peters et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.
Bookshelf ID: NBK537714
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