Achenbach Child Behaviour Checklist

Nicholas JA Webb; Rebecca L Woolley; Tosin Lambe; Emma Frew; Elizabeth A Brettell; Emma N Barsoum; Richard S Trompeter; Carole Cummins; Keith Wheatley; Natalie J Ives

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Webb NJA, Woolley RL, Lambe T, et al. Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome: the PREDNOS RCT. Southampton (UK): NIHR Journals Library; 2019 May. (Health Technology Assessment, No. 23.26.)

Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome: the PREDNOS RCT.

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Appendix 2Achenbach Child Behaviour Checklist

TABLE 21

Mean ACBC t-scores and total scores

Score	Group		Mean difference (95% CI)	p-value
Score	SC	EC	Mean difference (95% CI)	p-value
t-score
4 weeks
n	104	109
Mean (SD)	53.28 (12.37)	52.36 (12.36)	–0.92 (–4.26 to 2.42)	0.6
16 weeks
n	97	104
Mean (SD)	51.47 (13.10)	50.21 (13.91)	–1.26 (–5.03 to 2.50)	0.5
12 months
n	98	102
Mean (SD)	50.84 (15.52)	49.31 (13.31)	–1.52 (–5.55 to 2.50)	0.5
24 months
n	92	94
Mean (SD)	48.95 (13.81)	49.36 (13.54)	0.42 (–3.54 to 4.37)	0.8
36 months
n	61	61
Mean (SD)	49.07 (13.50)	48.87 (13.74)	–0.20 (–5.08 to 4.69)	0.9
48 months
n	32	28
Mean (SD)	50.13 (15.18)	46.61 (13.06)	–3.52 (–10.89 to 3.86)	0.3
Total
4 weeks
n	105	111
Mean (SD)	37.28 (26.83)	35.32 (25.86)	–1.96 (–9.03 to 5.11)	0.6
16 weeks
n	97	105
Mean (SD)	34.30 (27.37)	31.20 (27.10)	–3.10 (–10.66 to 4.46)	0.4
12 months
n	98	102
Mean (SD)	34.34 (31.67)	29.22 (24.88)	–5.12 (–13.09 to 2.85)	0.2
24 months
n	93	95
Mean (SD)	28.92 (26.37)	28.08 (25.15)	–0.84 (–8.25 to 6.57)	0.8
36 months
n	61	61
Mean (SD)	27.11 (25.11)	26.90 (26.15)	–0.21 (–9.40 to 8.98)	1.0
48 months
n	32	28
Mean (SD)	29.56 (27.77)	21.25 (21.06)	–8.31 (–21.20 to 4.57)	0.2

: A higher score is worse. A negative difference favours the EC group.

TABLE 22

Achenbach Child Behaviour Checklist normal scores

Score	Group		RR^a (95% CI)	p-value
Score	SC	EC	RR^a (95% CI)	p-value
Normal/abnormal scores
4 weeks
n	104	109
Normal score (%)	72 (69)	79 (72)
16 weeks
n	97	104
Normal score (%)	71 (73)	77 (74)	0.98 (0.86 to 1.10)	0.9
12 months
n	98	102
Normal score (%)	69 (70)	78 (76)	0.97 (0.84 to 1.12)	0.3
24 months
n	92	94
Normal score (%)	72 (78)	70 (74)	1.06 (0.92 to 1.23)	0.8
36 months
n	61	61
Normal score (%)	47 (77)	47 (77)	0.98 (0.83 to 1.14)	1.0
48 months
n	32	28
Normal score (%)	22 (69)	22 (79)	0.99 (0.73 to 1.35)	0.4

: ACBC t-scores are categorised as normal < 60 or abnormal ≥ 60.
a: Adjusting for 4-week ‘normal score’ status.

Copyright © Queen’s Printer and Controller of HMSO 2019. This work was produced by Webb et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Bookshelf ID: NBK541718

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Webb NJA, Woolley RL, Lambe T, et al. Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome: the PREDNOS RCT. Southampton (UK): NIHR Journals Library; 2019 May. (Health Technology Assessment, No. 23.26.) Appendix 2, Achenbach Child Behaviour Checklist.
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