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Reeves BC, Rooshenas L, Macefield RC, et al. Three wound-dressing strategies to reduce surgical site infection after abdominal surgery: the Bluebelle feasibility study and pilot RCT. Southampton (UK): NIHR Journals Library; 2019 Aug. (Health Technology Assessment, No. 23.39.)

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Three wound-dressing strategies to reduce surgical site infection after abdominal surgery: the Bluebelle feasibility study and pilot RCT.

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Chapter 6Conclusion

We have shown that a main trial of different dressing strategies, including no dressing, is feasible and would be valuable to the NHS. Patients and practitioners supported the premise of a future trial of dressing types and engaged with the idea that there is equipoise in this area. This engagement was also reflected through the excellent participation in both the qualitative and the quantitative studies, the high consent rate and good adherence to allocation.

We have also developed, validated and tested a new tool, the WHQ, for assessing SSI, which can be used by patients after hospital discharge. This tool has immense potential to improve the efficiency of studies evaluating interventions to reduce SSI.

The NHS now needs to decide whether the research question in a main trial should be specifically about the effect of different dressing strategies, or about the combined effect of different dressing strategies and their effect on wound closure and whether a two-group or three-group trial is needed. There is also the need to consider whether this evaluation should be a standalone study or whether an existing study should be adapted to include glue-as-a-dressing and no dressing groups.

Copyright © Queen’s Printer and Controller of HMSO 2019. This work was produced by Reeves et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.
Bookshelf ID: NBK545012

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