- Chronic thromboembolic pulmonary hypertension
Persistent increased blood pressure in the arteries supplying the lungs, which is caused by pulmonary embolism and results in long-term shortness of breath and fatigue.
- Cost-effectiveness acceptability curve
A way of illustrating cost-effectiveness results by plotting the probability that the intervention is cost-effective (y-axis) against the maximum that society is willing to pay for an improvement in health (x-axis).
- Cost-effectiveness plane
A way of illustrating cost-effectiveness results by plotting the mean incremental cost and effectiveness on a four-quadrant graph. Interventions that are more costly and more effective fall in the north-east quadrant.
- Deep-vein thrombosis
A blood clot that develops within a deep vein in the body, usually in the leg.
- Incremental cost-effectiveness ratio
The difference in the mean costs in the population of interest divided by the differences in the mean outcomes in the population of interest.
- L-TRiP(cast)–N
A strategy of giving thromboprophyalxis to patients with a L-TRiP(cast) score of N or above.
- Post-thrombotic syndrome
Pain, swelling, itching, skin discolouration and leg ulcers occurring after a deep-vein thrombosis, caused by damage to the valves in the leg veins that prevent backflow of blood.
- Predictor
Throughout this report, ‘predictor’ is used to refer to any clinical, laboratory or demographic characteristic. The term ‘predictor’ encompasses other similar terms, such as prognostic factor, covariate and variable.
- Prophylaxis
A measure taken to prevent a disease.
- Pulmonary embolism
A blood clot that breaks off from the deep veins and travels around the circulation to block the pulmonary arteries (arteries in the lung). Most deaths arising from deep-vein thrombosis are caused by pulmonary embolism.
- Quality-adjusted life-year
A measure of the benefit of health care that combines the impact of both the expected length of life and quality of life.
- Risk assessment models
In this report, defined as a combination of at least two predictors within a statistical model that is used to predict an individual’s risk of outcome, for example venous thromboembolism. Other terms also related to risk assessment models may include prognostic model, prediction models, clinical decision rules and clinical prediction guides. The term ‘risk assessment model’ is used in this report to encompass all of these terms; therefore, all are considered to refer to the same thing.
- Thromboprophylaxis
A measure taken to reduce the risk of thrombosis.
- Vein thrombosis
A condition in which a blood clot (thrombus) forms in a vein.
- Venous thromboembolism
The blocking of a blood vessel by a blood clot dislodged from its site of origin. It includes both deep-vein thrombosis and pulmonary embolism.
