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Lindsay Claxton; Mark Simmonds; Lucy Beresford; Richard Cubbon; Mark Dayer; Stephen S Gottlieb; Nick Hartshorne-Evans; Bruce Kilroy; Alexis Llewellyn; Claire Rothery; Sahar Sharif; Jayne F Tierney; Klaus K Witte; Kath Wright; Lesley A Stewart

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Claxton L, Simmonds M, Beresford L, et al. Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation. Southampton (UK): NIHR Journals Library; 2022 Jan. (Health Technology Assessment, No. 26.4.)

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Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation.

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6MWT: 6-minute walk test
ACE: angiotensin-converting enzyme
ACM: all-cause mortality
BNF: British National Formulary
BNP: B-type natriuretic peptide
CEAC: cost-effectiveness acceptability curve
CENTRAL: Cochrane Central Register of Controlled Trials
CHF: chronic heart failure
CI: confidence interval
co-Q10: coenzyme Q10
CPRD: Clinical Practice Research Datalink
ECHOES: EchoCardiographic Heart Of England Screening
EPHESUS: Eplerenone Post-AMI Heart Failure Efficacy and Survival Study
EQ-5D: EuroQol-5 Dimensions
EVPI: expected value of perfect information
FAS: full analysis set
GLMM: generalised linear mixed model
GP: general practitioner
HES: Hospital Episode Statistics
HFpEF: heart failure with a preserved ejection fraction
HFrEF: heart failure with a reduced ejection fraction
HR: hazard ratio
HRG: Healthcare Resource Group
HRQoL: health-related quality of life
ICER: incremental cost-effectiveness ratio
IPD: individual participant data
IQR: interquartile range
LVEF: left ventricular ejection fraction
LVSD: left ventricular systolic dysfunction
MD: mean difference
MI: myocardial infarction
MLWHFQ: Minnesota Living with Heart Failure Questionnaire
NICE: National Institute for Health and Care Excellence
NMA: network meta-analysis
NT-pro-BNP: N-terminal pro-B-type natriuretic peptide
NYHA: New York Heart Association
ONS: Office for National Statistics
OR: odds ratio
PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses
QALY: quality-adjusted life-year
QoL: quality of life
RCT: randomised controlled trial
RR: relative risk
SHIFT: Systolic Heart failure treatment with the IF inhibitor ivabradine Trial
SHOCS: Scale for Heart failure to Optimise Clinical Status
SMD: standardised mean difference
THIN: The Health Improvement Network
VOI: value of information

Copyright © 2022 Claxton et al. This work was produced by Claxton et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaption in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.

Bookshelf ID: NBK577327

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Claxton L, Simmonds M, Beresford L, et al. Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation. Southampton (UK): NIHR Journals Library; 2022 Jan. (Health Technology Assessment, No. 26.4.) List of abbreviations.
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Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation.

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