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Headline
A preconception intervention that asks women to delay long-acting reversible contraception removal would be neither acceptable nor feasible, but a preconception health programme that included weight management could be acceptable.
Abstract
Background:
Women with overweight (a body mass index of ≥ 25 kg/m2) or obesity (a body mass index of ≥ 30 kg/m2) are at greater risk of experiencing complications during pregnancy and labour than women with a healthy weight. Women who remove their long-acting reversible contraception (i.e. coils or implants) are one of the few groups of people who contact services as part of their preparation for conception, creating an opportunity to offer a weight loss intervention.
Objectives:
The objectives were to understand if routine NHS data captured the pathway from long-acting reversible contraception removal to pregnancy and included body mass index; to identify the suitable components of a preconception weight loss intervention; and to engage with key stakeholders to determine the acceptability and feasibility of asking women with overweight/obesity to delay the removal of their long-acting reversible contraception in order to take part in a preconception weight loss intervention.
Design:
This was a preparatory mixed-methods study, assessing the acceptability and feasibility of a potential intervention, using routine NHS data and purposefully collected qualitative data.
Participants:
The NHS routine data included all women with a long-acting reversible contraception code. There were three groups of participants in the surveys and interviews: health-care practitioners who remove long-acting reversible contraception; weight management consultants; and women of reproductive age with experience of overweight/obesity and of using long-acting reversible contraception.
Setting:
UK-based health-care practitioners recruited at professional meetings; and weight management consultants and contraceptive users recruited via social media.
Data sources:
Anonymised routine data from UK sexual health clinics and the Clinical Practice Research Datalink, including the Pregnancy Register; and online surveys and qualitative interviews with stakeholders.
Results:
The records of 2,632,871 women aged 16–48 years showed that 318,040 had at least one long-acting reversible contraception event, with 62% of records including a body mass index. Given the identified limitations of the routine NHS data sets, it would not be feasible to reliably identify women with overweight/obesity who request a long-acting reversible contraception removal with an intention to become pregnant. Online surveys were completed by 100 health-care practitioners, four weight management consultants and 243 contraceptive users. Ten health-care practitioners and 20 long-acting reversible contraception users completed qualitative interviews. A realist-informed approach generated a hypothesised programme theory. The combination of weight discussions and the delay of long-acting reversible contraception removal was unacceptable as an intervention to contraceptive users for ethical and practical reasons. However, a preconception health intervention incorporating weight loss could be acceptable, and one potential programme is outlined.
Limitations:
There was very limited engagement with weight management consultants, and the sample of participating stakeholders may not be representative.
Conclusions:
An intervention that asks women to delay long-acting reversible contraception removal to participate in a preconception weight loss intervention would be neither feasible nor acceptable. A preconception health programme, including weight management, would be welcomed but requires risk communication training of health-care practitioners.
Future work:
Work to improve routine data sets, increase awareness of the importance of preconception health and overcome health-care practitioner barriers to discussing weight as part of preconception care is a priority.
Trial registration:
This trial is registered as ISRCTN14733020.
Funding:
This project was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 27, No. 1.
Contents
- Plain English summary
- Scientific summary
- Chapter 1. Introduction and background
- Chapter 2. Methods
- Study design
- Work package 1: defining and understanding the population through routine data
- Work package 2: understanding context and stakeholder views
- Work package 2 phase 1: realist review – scoping suitable interventions and underlying theories
- Work package 2 phase 1: understanding the preconception pathways relating to LARC
- Engagement with service providers (health-care and weight loss practitioners)
- Summary of phase 1 findings
- Phase 2: acceptability and feasibility of proposed intervention
- Study flow
- Literature review methods
- Study setting and participant selection/recruitment
- Eligibility criteria
- Informed consent
- Data management and confidentiality
- Analysis
- Withdrawal
- Ethics
- Participant and public involvement
- Changes to the protocol
- Chapter 3. Routine data work package
- Chapter 4. Understanding preconception pathways relating to LARC through qualitative surveys and analysis of policy documents
- Chapter 5. Realist review
- Chapter 6. Work package 2: phase 1 stakeholder advisory groups
- Chapter 7. Phase 2: acceptability and feasibility of proposed intervention
- Chapter 8. Discussion
- Acknowledgements
- References
- Appendix 1. Defining LARC events using Read codes and British National Formulary prescription codes
- Appendix 2. Clinical codes
- Appendix 3. Routine data results
- Appendix 4. Sexual health clinic data: open access
- Appendix 5. Data cleaning flow chart for body mass index
- Appendix 6. Search strategies and results
- Appendix 7. Policy review results
- Appendix 8. Review paper results
- Appendix 9. Weight management in pregnancy key studies
- Appendix 10. Barriers and facilitators
- Appendix 11. Key qualitative and survey-based literature
- Appendix 12. Explanatory accounts
- Appendix 13. Consolidated explanatory accounts
- Appendix 14. Consolidated explanatory accounts grouped by outcome
- List of abbreviations
- List of supplementary material
About the Series
Declared competing interests of authors: Rebecca Cannings-John was a National Institute for Health and Care Research (NIHR) Health Technology Assessment Associate Board member (16 May 2018 to 30 November 2020). Freya Davies was a co-applicant and named researcher at a research centre funded by Health and Care Research Wales [PRIME (Wales Centre for Primary and Emergency Care)]. Caroline Scherf received financial support from Gedeon Richter for attending the European Society of Contraception and Reproductive Health meeting in 2018 in Budapest. Julia Sanders acts as a self-employed independent midwifery expert witness and is chief investigator of the NIHR-funded POOL study, co-investigator of the NIHR-funded CHOICE study, co-investigator of the NIHR-funded iHOLDS study, co-investigator of the NIHR funded HOLDS study, co-investigator of the NIHR funded ANODE study and a funded co-investigator with Policy Research Unit NPEU, University of Oxford (Oxford, UK).
Article history
The research reported in this issue of the journal was funded by the HTA programme as project number 17/130/05. The contractual start date was in May 2019. The draft report began editorial review in May 2021 and was accepted for publication in October 2021. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The HTA editors and publisher have tried to ensure the accuracy of the authors’ report and would like to thank the reviewers for their constructive comments on the draft document. However, they do not accept liability for damages or losses arising from material published in this report.
Disclaimer
This report contains transcripts of interviews conducted in the course of the research, or similar, and contains language which may offend some readers.
Last reviewed: May 2021; Accepted: October 2021.
- NLM CatalogRelated NLM Catalog Entries
- The acceptability of asking women to delay removal of a long-acting reversible contraceptive to take part in a preconception weight loss programme: a mixed methods study using qualitative and routine data (Plan-it).[BMC Pregnancy Childbirth. 2022]The acceptability of asking women to delay removal of a long-acting reversible contraceptive to take part in a preconception weight loss programme: a mixed methods study using qualitative and routine data (Plan-it).Channon S, Coulman E, Cannings-John R, Henley J, Lau M, Lugg-Widger F, Strange H, Davies F, Sanders J, Scherf C, et al. BMC Pregnancy Childbirth. 2022 Oct 18; 22(1):778. Epub 2022 Oct 18.
- An interactive website to aid young women's choice of contraception: feasibility and efficacy RCT.[Health Technol Assess. 2020]An interactive website to aid young women's choice of contraception: feasibility and efficacy RCT.Stephenson J, Bailey JV, Blandford A, Brima N, Copas A, D'Souza P, Gubijev A, Hunter R, Shawe J, Rait G, et al. Health Technol Assess. 2020 Nov; 24(56):1-44.
- Practice nurse-supported weight self-management delivered within the national child immunisation programme for postnatal women: a feasibility cluster RCT.[Health Technol Assess. 2021]Practice nurse-supported weight self-management delivered within the national child immunisation programme for postnatal women: a feasibility cluster RCT.Daley AJ, Jolly K, Ives N, Jebb SA, Tearne S, Greenfield SM, Yardley L, Little P, Tyldesley-Marshall N, Bensoussane H, et al. Health Technol Assess. 2021 Aug; 25(49):1-130.
- Canadian Contraception Consensus (Part 1 of 4).[J Obstet Gynaecol Can. 2015]Canadian Contraception Consensus (Part 1 of 4).Black A, Guilbert E, Co-Authors, Costescu D, Dunn S, Fisher W, Kives S, Mirosh M, Norman WV, Pymar H, et al. J Obstet Gynaecol Can. 2015 Oct; 37(10):936-42.
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