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Links from Conserved Domains

Items: 1 to 20 of 115

2.
Molecular Structure Image for smart00252

SH2: Src homology 2 domains

Src homology 2 domains bind phosphotyrosine-containing polypeptides via 2 surface pockets. Specifici...

3.
Molecular Structure Image for cd10417

SH2_SH2D7: Src homology 2 domain found in the SH2 domain containing protein 7 (SH2D7)

SH2D7 contains a single SH2 domain. In general SH2 domains are involved in signal transduction. They...

4.
Molecular Structure Image for cd10369

SH2_Src_Frk: Src homology 2 (SH2) domain found in the Fyn-related kinase (Frk)

Frk is a member of the Src non-receptor type tyrosine kinase family of proteins. The Frk subfamily i...

5.
Molecular Structure Image for cd10349

SH2_SH2D2A_SH2D7: Src homology 2 domain found in the SH2 domain containing protein 2A and 7 (SH2D2A and SH2D7)

SH2D2A and SH7 both contain a single SH2 domain. In general SH2 domains are involved in signal trans...

6.
Molecular Structure Image for cd10341

SH2_N-SH2_PLC_gamma_like: N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma

Phospholipase C gamma is a signaling molecule that is recruited to the C-terminal tail of the recept...

7.
Molecular Structure Image for cd09941

SH2_Grb2_like: Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins

The adaptor proteins here include homologs Grb2 in humans, Sex muscle abnormal protein 5 (Sem-5) in ...

8.
Molecular Structure Image for cd09933

SH2_Src_family: Src homology 2 (SH2) domain found in the Src family of non-receptor tyrosine kinases

The Src family kinases are nonreceptor tyrosine kinases that have been implicated in pathways regula...

9.
Molecular Structure Image for cd10718

SH2_CIS: Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)

CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The...

10.
Molecular Structure Image for cd10421

SH2_STAT5a: Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins

STAT5 is a member of the STAT family of transcription factors. Two highly related proteins, STAT5a ...

11.
Molecular Structure Image for cd10420

SH2_STAT5b: Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins

STAT5 is a member of the STAT family of transcription factors. Two highly related proteins, STAT5a ...

12.
Molecular Structure Image for cd10419

SH2_Src_Fyn_isoform_b_like: Src homology 2 (SH2) domain found in Fyn isoform b like proteins

Fyn is a member of the Src non-receptor type tyrosine kinase family of proteins. This cd contains th...

13.
Molecular Structure Image for cd10418

SH2_Src_Fyn_isoform_a_like: Src homology 2 (SH2) domain found in Fyn isoform a like proteins

Fyn is a member of the Src non-receptor type tyrosine kinase family of proteins. This cd contains th...

14.
Molecular Structure Image for cd10416

SH2_SH2D2A: Src homology 2 domain found in the SH2 domain containing protein 2A (SH2D2A)

SH2D2A contains a single SH2 domain. In general SH2 domains are involved in signal transduction. Th...

15.
Molecular Structure Image for cd10415

SH2_Grb10: Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins

The Grb family binds to the epidermal growth factor receptor (EGFR, erbB1) via their SH2 domains. Gr...

16.
Molecular Structure Image for cd10414

SH2_Grb14: Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins

The Grb family binds to the epidermal growth factor receptor (EGFR, erbB1) via their SH2 domains. Gr...

17.
Molecular Structure Image for cd10413

SH2_Grb7: Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins

The Grb family binds to the epidermal growth factor receptor (EGFR, erbB1) via their SH2 domains. Gr...

18.
Molecular Structure Image for cd10412

SH2_SH2B3: Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)

SH2B3 (Lnk), like other members of the SH2B adapter protein family, contains a pleckstrin homology d...

19.
Molecular Structure Image for cd10411

SH2_SH2B2: Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)

SH2B2 (APS), like other members of the SH2B adapter protein family, contains a pleckstrin homology d...

20.
Molecular Structure Image for cd10410

SH2_SH2B1: Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)

SH2B1 (SH2-B, PSM), like other members of the SH2B adapter protein family, contains a pleckstrin hom...

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