Conserved Protein Domain Family
CxxCH_TIGR02603

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TIGR02603: CxxCH_TIGR02603 
putative heme-binding domain, Pirellula/Verrucomicrobium type
This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190).
Statistics
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PSSM-Id: 274224
Aligned: 9 rows
Threshold Bit Score: 183.329
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_029190666  718 PDLAQGREVFFHPrlggCVLCHRIDGVGSPAGPNLSTI-GaT-K-SPDYILESLLQPSRNVPPLYES-YNLTTSDGkART 793  Verrucomicrob...
WP_009963370 1118 GDAAKGKIVFMTV----CMVCHKVKGEGMDVGPDITDV-K-L-K-EKEALLSDILDPNRMVEARWSA-YQIDTREG-RIV 1187 Verrucomicrob...
WP_009959696  674 GNADRGEKVYQKA----CIACHQLGLAGVEVGPNLATV-A-A-K-PVEQLMEAILDPNRAVEQRNAT-TQVTKKDG-SIL 743  Verrucomicrob...
WP_009960009  873 ADASAGRVIFNQV----CAACHKLYGEGNLIGPDLTGS-G-R-K-DVNYLIENIADPSATLAADYKM-SVVNLKDG-RIL 942  Verrucomicrob...
WP_009958829  900 GDAARGQLVFMQR----CFTCHRAAGQGFQVGPDLITV-K-T-K-GREALLSAILDPNKEVAPQFIA-YTVETQDG-QTL 969  Verrucomicrob...
WP_009958230 1362 GDVEKGKAIYAKAes-tCTLCHRVGNIGADFGPGLTEI-G-S-KlGKEVIYESIINPNAGVSMGFET-WQITLKNG-TVA 1435 Verrucomicrob...
WP_009961812  793 GDATRGKTAVAT-----CYTCHKIGEPGVDFGPDLTVF-GkT-Q-TREVLLNAIINPSGDIAHGYEG-KRIVTKDG-VTI 862  Verrucomicrob...
WP_029190804 1080 ADPEKGKQVAA-R----CMMCHRIDGAGVDYGPNLAGWvA-N-Q-GAVPFIKALVNPSETIALGFEG-ERVPLKDG-REV 1149 Verrucomicrob...
WP_009964735  757 GDAKRGEAKVA-V----CYVCHQVGAQGTPFGPNLAGW-A-AaR-TTEQILTDLIAPSERLAHGFDQpARLRSRDGkHIV 828  Verrucomicrob...
WP_029190666  794 AFQLMe---RGNVHTYVGLDGRSFDVKIEE--I-TKREHLPVSIMPEGMVARLSDAQIRDLVEYLKSK 855  Verrucomicrobium spinosum
WP_009963370 1188 SGLIAs--eSADAVTVKMAGGITEVLPRGS--I-SKMKSLDASLMPVGLEGGISKEQMADLLAFLKGE 1250 Verrucomicrobium spinosum
WP_009959696  744 AGLIAa--eTPGAISLRLPGGVDLPVPRSE--I-GSIKTLPVSLMPDGLESIVSPQDMADLLARLRKL 806  Verrucomicrobium spinosum
WP_009960009  943 SGNIAa--kTDRTLTIKMV-GQEQVVERGD--I-TSIQELPVSLMPEGLLLALTDEQVRNLMAYLTSD 1004 Verrucomicrobium spinosum
WP_009958829  970 GGLLSk--dDTSGVTVRMTAGAEVNIARAQ--V-KKMSAGGLSLMPEGLEAGMDAQGMADLLEFVETL 1032 Verrucomicrobium spinosum
WP_009958230 1436 MGIVRs--eTNDELVLALPGGVANSFNKQQ--I-AERKKLPNTMMPSGLQSMFSQEDLVNLVEYLASL 1498 Verrucomicrobium spinosum
WP_009961812  863 DGMVLs---NDDPVQIKSMGGVIQAVPKRL--I-KSTTGMKHSLMFTADMMGLNAQALADIVAYLKSD 924  Verrucomicrobium spinosum
WP_029190804 1150 QGIVIs---AADPITVRSTGGLTQMIPREM--LrDRTAPLNRSLMLSAEEMGLTAQDLADLAAYMKTM 1212 Verrucomicrobium spinosum
WP_009964735  829 EGLVSnyshHAGSLNIKVFGGQMKKILFREggI-KVEFLKDHSWMPPASEMGLTDQDLRDLVEYLKSI 895  Verrucomicrobium spinosum
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