Conserved Protein Domain Family
WxL

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pfam13731: WxL 
WxL domain surface cell wall-binding
The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.
Statistics
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PSSM-Id: 433439
Aligned: 56 rows
Threshold Bit Score: 97.4271
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015077000     27 DKTADTKGSVQFEK-VGenevgeVVKPdTEdkPENiivP-------------EGGGN--TTGP-LRLQHVP-DIKFGTVt 88   Carnobacter...
jgi:EAT1b_1177   25 AMSGETEATIEFTElGVp----dIYDPaTDa-PFS---Pqpd-------sndGFVNT--TAAE-LTLDFAP-NLYFGTH- 84  
CCC80427         32 AATTQSQVQVEMTPsDDd----nAVSP-VD--PDD---PskpypgdpvdednvAGTG--SRGK-LTIDFVS-NLKFNAIt 97  
WP_015075186    539 TKDLTSEFTVTVTQpG-------ASKP-ID--PTN---Pqpgne----tdaeNEGTG--NIGY-LRVDYAPsNFDFGKV- 597  Carnobacter...
WP_011102288     41 NTTGTTDIQAMFEGnSS------PVSP-VN--PDN---Pnkpd------nsgDSGNGakAGGG-LSLIYVSnKLDFGSHe 101  Lactiplanti...
EQC81373         14 AANITTEGKVKILEnD-------SSNP-VVsdPEN---Pgnevtpe--------eptnpypGL-LRINYVS-NFDFGQIq 72  
WP_015077474     33 TGISDVNVSVEIGEdGG------PTIPpID--PEN---Pepp-------vdpGPGNP--HIGE-LSIRYIS-NLVFPTL- 89   Carnobacter...
Q82ZI1         1243 YSGVSTSATVRVKDnDQa-----IVTP-----------T--------------------AEGF-ISVP----TFNFGQVg 1281 Enterococcu...
WP_118232062     31 NRSGTTNATATFTAnTTn-----PVDP-VD--PTD---Ptkpld---pkpgdGDNGA--NSGAgLSLIYAPgKLDFGSHe 94   Lactiplanti...
WP_097558138     25 DSTANTTTNLELTEnTG------PTIP-VD--PTN---Panpqv---pedpdNPATG--NTGA-LTLDVAPrTFDFGSVq 86   Lactiplanti...
WP_015077000     89 --fKTGNT---KHQAILEnytk----dgvaGDQAIPQF---VQVTDERg--DD-TGtWKVTVSGT-TFKekvagggPATV 152  Carnobacter...
jgi:EAT1b_1177   85 ---TVRDTmalEYVAQPT------------VTGSKLPRsllVQVTDRR---TT-FGnWSVHVKAT-PFErt----sEVGV 140 
CCC80427         98 --tAGGPF---KTTAKNEwa--------------------mIQITDRRa--TA-AG-WTLQVTPSg---------lQSGQ 139 
WP_015075186    598 ----TTSFlnkTYQANQPls--------vsGKTLTQQW---IQVSDTRl--SD-NG-WTLSVSQStPFI-------GSDG 651  Carnobacter...
WP_011102288    102 i-dVLNPE---TYTAAETd----------sDLSGLWNKkavTEVSDVRg--SN-AG-WTLAVAGS-SLT-------GTDG 155  Lactiplanti...
EQC81373         73 n--vSRAI---EQKARLDhvw------vngEEVSRVPF---VATEDRRg--SErLG-WELQVLQPnQLA-------DASG 128 
WP_015077474     90 ---PASTEttvVYADQDR-------------NENDETFdnmVTIQDFRndaNR-DG-WELSVKQD-------------TN 138  Carnobacter...
Q82ZI1         1282 vagSTQQH---SLKKAADy----------yGNGTRNPY---LRIKKTQ------AN-WSLTAQLS-QPKsatdslpTATR 1337 Enterococcu...
WP_118232062     95 i-dVINNQ---SYKALTGsdgstvtmgstsKVG--------LQVSDQRg--TN-AG-WTLSVAAAdg--------tDGNL 150  Lactiplanti...
WP_097558138     87 t--yAAEH---TYKATTT--------------TNGQQY---LQVTDNRg--TDeQG-WTVTVEQDqDLTet----sGSSP 137  Lactiplanti...
WP_015077000    153 PELVNTKIVV------KQQkffntVTDYATPVVSaetl------------vsgfTGTELTipTNGTDSVLVMqtKAGKST 214  Carnobacter...
jgi:EAT1b_1177  141 PSLPGAYFTF------NGGavkspIGDTDSPVLS--------------------SGNIQL--NTDNQYVNVM--SAAANT 190 
CCC80427        140 QTLT-TSLKLg-----AVQ-----LRPGAGNVSTapn--------------vvnTGELVA-----GLANNVV--IAPPNT 187 
WP_015075186    652 STLEGAQLKI------PKGkiyntASNSEPIIDNsi-----------------iSRGVSL----SETPTAILttPKVNAS 704  Carnobacter...
WP_011102288    156 SVMKGATLQLp-----KGTvtnsgATNNG-------------------------VQSTEAlnVLDGNSATVL--SAAKDH 203  Lactiplanti...
EQC81373        129 HELIGATITLsglryvNATaatpiVN----------------------------QNEIVL----GAAAQTLA--TADAAQ 174 
WP_015077474    139 SFIPGSFITM------TPYvhptiAAEYQIQTPS--------------------ASGLRL-----NNAEQVFarTESQEN 187  Carnobacter...
Q82ZI1         1338 LLLGAAPVSS--------------FSNYNQPTELkna--------------vgtTSAISL--NANNTATRII--ANQQFT 1385 Enterococcu...
WP_118232062    151 STLKGATVSLp-----AGT-----VISSGSEASNgstggngavgqaveldlgsqASTSAGasFTGTTSGNVM--TAADKS 218  Lactiplanti...
WP_097558138    138 HVLTGTTIHV------PAG-----IARNSLATDPtav--------------dtnLTTTAAdvTNTSGAVTVFntTATTGA 192  Lactiplanti...
WP_015077000    215 NGSKTSVVFNSDytdassyvvgekNAGIILDKANGDNIVVDkaYESDLTWTLS 267  Carnobacterium maltaromaticum
jgi:EAT1b_1177  191 GQFTWLAHWTGA------------GASVKLHVANNMMQVGQ--HVSKLTWSLT 229 
CCC80427        188 GLGTWLVVLNRG------------QVPTELEVHDRQLRAGD--YTGTLAWSLT 226 
WP_015075186    705 GKNITTNVWD--------------PTQVSLYVPGGSAKNKVr-YQTTINWSLV 742  Carnobacterium maltaromaticum
WP_011102288    204 GAGVTVDQID--------------PSNVKLTVPANTAKAQG--YQTTLNWSLS 240  Lactiplantibacillus plantarum
EQC81373        175 GSGAWALALGQSnge-------ghTDGVVLRIPANTTANNTe-YSTAIVWELV 219 
WP_015077474    188 PSGIVSIGFANPe-----------MDGVELSVPANTP---VgdYKTTITWNLS 226  Carnobacterium maltaromaticum
Q82ZI1         1386 GSNIYQLDFT--------------FNNVKLEVPANQGVKGQq-YQAAITWNLV 1423 Enterococcus faecalis
WP_118232062    219 GAGITSDLLD--------------PAAVKLNVVANTAAATT--YKGVLNWTLT 255  Lactiplantibacillus plantarum
WP_097558138    193 GKGTSVKVWD--------------PSDVTLTIPKNTAKPGA--YSNTLTWTLT 229  Lactiplantibacillus plantarum
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