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HMG-box_SF: high mobility group (HMG)-box domain superfamily
The High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and trans...
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HMG-box_SoxF_SOX18: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 18 (SOX18) and similar proteins
SOX-18 is a transcription factor involved in the development of cardiovascular and lymphatic vessels...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
HMG-box_SoxF_SOX17: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 17 (SOX17) and similar proteins
SOX-17 is a developmental transcription regulator involved in endoderm formation, angiogenesis, and ...
HMG-box_SoxF_SOX7: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 7 (SOX7) and similar proteins
SOX-7 is an endothelial-associated transcription factor that acts as a tumor suppressor in a number ...
HMG-box_EGL13-like: high mobility group (HMG)-box found in Caenorhabditis elegans protein egg laying defective 13 (EGL-13) and similar proteins
EGL-13 may act as a transcription factor that is required for uterine cell fate decisions in Caenorh...
HMG-box_SoxC_SOX12: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 12 (SOX12) and similar proteins
SOX-12, also called SOX-22, is a transcription factor essential for embryonic development and cell f...
HMG-box_SoxC_SOX11: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 11 (SOX11) and similar proteins
SOX-11 is a neural transcriptional factor involved in precursor survival, neuronal fate determinatio...
HMG-box_SoxC_SOX4: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 4 (SOX4) and similar proteins
SOX-4 is a transcriptional activator that promotes neuronal differentiation both in the adult and em...
HMG-box_SoxG_SOX15: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 15 (SOX15) and similar proteins
SOX-15, also called SOX-12, SOX-20, SOX-26, or SOX-27, is a crucial transcription factor involved in...
HMG-box_SoxA_SRY: high mobility group (HMG)-box found in sex-determining region Y protein (SRY) and similar proteins
SRY, also called testis-determining factor, is a transcriptional regulator that controls a genetic s...
HMG-box_SoxH_SOX30: high mobility group (HMG)-box found in sex determining region Y (SRY)-box 30 (SOX30) and similar proteins
SOX-30 is a crucial transcription factor that controls the transition from a late meiotic to a post-...
HMG-box_SoxF: high mobility group (HMG)-box found in group F SRY-related high-mobility group (HMG) box (Sox) transcription factors
SoxF transcription factors includes three members: Sox7, Sox17, and Sox18. They regulate endothelial...
HMG-box_SoxE: high mobility group (HMG)-box found in group E SRY-related high-mobility group (HMG) box (Sox) transcription factors
SoxE transcription factors includes three members: Sox8, Sox9, and Sox10. They function as important...
HMG-box_SoxD: high mobility group (HMG)-box found in group D SRY-related high-mobility group (HMG) box (Sox) transcription factors
SoxD transcription factors includes three members, Sox5, Sox6, and Sox13. They function as important...
HMG-box_SoxC: high mobility group (HMG)-box found in group C SRY-related high-mobility group (HMG) box (Sox) transcription factors
SoxC transcription factors includes three members: SOX4, SOX11 and SOX12. They play key roles, often...
HMG-box_SoxA_SoxB_SoxG: high mobility group (HMG)-box found in group A, group B and group G of SRY-related high-mobility group (HMG) box (Sox) transcription factors
This subfamily includes SoxA, SoxB, and SoxG proteins. SRY is the only member of group A SRY-related...
HMG-box_KMT2D: high mobility group (HMG)-box found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
KMT2D, also called ALL1-related protein (ALR), is encoded by the gene that was named myeloid/lymphoi...
HMG-box_KMT2C: high mobility group (HMG)-box found in histone-lysine N-methyltransferase 2C (KMT2C) and similar proteins
KMT2C, also called myeloid/lymphoid or mixed-lineage leukemia protein 3 (MLL3) or homologous to ALR ...
HMG-box_HMG20B: high mobility group (HMG)-box found in high mobility group protein 20B (HMG20B) and similar proteins
HMG20B, also called SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfami...
HMG-box_HMG20A: high mobility group (HMG)-box found in high mobility group protein 20A (HMG20A) and similar proteins
HMG20A, also called HMG box-containing protein 20A, HMG domain-containing protein 1 (HMGXB1), HMG do...
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