Conserved Protein Domain Family
ILWEQ

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smart00307: ILWEQ 
I/LWEQ domain
Thought to possess an F-actin binding function.
Statistics
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PSSM-Id: 214607
Aligned: 11 rows
Threshold Bit Score: 231.102
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_715249  857 GGNIEVDEMLLACAKAITDAVAELIKASIKSQQEIIS--KGGTTKSDFYKKNSRWTEGLISASKAVAGATNVLIHTADGV 934  Candida albicans...
AAC33564   772 GVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVEsgRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLV 851  human
NP_594069  892 PSELQVHDSLLSASIAITEAIARLIKAATASQAEIVAqgRGSSSRGAFYKKHNRWTEGLISAAKAVARATTTLIETADGV 971  Schizosaccharomy...
BAA31630   829 GVKLEVNERILNSCTDLMKAIRLLVTTSTSLQKEIVEsgRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVEAADKV 908  human
S44664     716 GIRLEVNESILANCQALMSVIMQLVIASRELQTEIVAagKAGGSPAEFYKRNHQWTEGLLSAAKAVGVAARVLVESADGV 795  nematode
AAC83184   843 TTDLQLHEAAIQAAQAVINAIAALIRAATDAQNEIVAqgRGTSSRAQFYKKNNKWTEGLISAAKSVAASTNILIEKADGT 922  Yarrowia lipolytica
EDN62582   759 HLRVDVPKPLLSLALMIIDAVVALVKAAIQCQNEIAT--TTSIPLNQFYLKNSRWTEGLISAAKAVAGATNVLITTASKL 836  Saccharomyces ce...
EDL98751  2372 DESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAqgKVGAIPANALD-DGQWSQGLISAARMVAAATNNLCEAANAA 2450 Norway rat
BAA75511  2265 IDEAGIDESILEAARAITSATGVLVQCATNVQHELVLagKVG-NKGNMYRRDPTWARGLISAAQAVAGSVQGLVHSANSS 2343 Dictyostelium di...
NP_490886 2357 IVETEFDDNIIISAKGILHAVHTLMRSASNAQRELAMqgRAAAGGTGTY----QWSEGLISAARVVVASVHKLCDAANTL 2432 nematode
P0CE95    2294 LDAEGVAATIVDASSAIAKAVAKLVNSAAVAQSKRREdqIAS---GSVYKADPTWSNGLISAAKGVGAATHRLVEAAMKS 2370 Dictyostelium di...
XP_715249  935 LK----QSNSHEELIVASNEVAASTAQLVAASRVKANFVSQ---AQDNLEIASSNVSKACKSLVVKVEGLLIRkdeegEK 1007 Candida albicans...
AAC33564   852 VQ----GRGKFEELMVCSHEIAASTAQLVAASKVKADKDSP---NLAQLQQASRGVNQATAGVVASTISGKSQ-----IE 919  human
NP_594069  972 VN----GTSSFEHLIVACNGVSAATAQLVAASRVKANFASK---VQDHLEDAAKAVTEACKALVRQVESVALk-----AK 1039 Schizosaccharomy...
BAA31630   909 VL----HTGKYEELIVCSHEIAASTAQLVAASKVKANKHSP---HLSRLQECSRTVNERAANVVASTKSGQEQ-----IE 976  human
S44664     796 VT----GKGKFEHLIVAAQEIAASTAQLFVSSRVKADKDSS---KLDALSVAAKAVNQNTAQVVAAVKNGQTT-----LN 863  nematode
AAC83184   923 LR----RTSGLEELIVASNNVAASTAQLVAASRVKATFMSK---TQDKLEECSKVVTSACRNLVKQVQEILNKk---fGE 992  Yarrowia lipolytica
EDN62582   837 ITsednENTSPEQFIVASKEVAASTIQLVAASRVKTSIHSK---AQDKLEHCSKDVTDACRSLGNHVM-GMIEddhstSQ 912  Saccharomyces ce...
EDL98751  2451 VQ----GHASQEKLISSAKQVAASTAQLLVACKVKADQDSE---AMKRLQAAGNAVKRASDNLVKAAQKAAAFe-----D 2518 Norway rat
BAA75511  2344 SQ----GKVDEEQLVASAKGVAAATARLVTASRAKADLNSA---SNSQLAQAAKQVSNATAALVEAAKQVNE-------E 2409 Dictyostelium di...
NP_490886 2433 MK----GQTTEERLISAAKQVSSSTAQLLVACNVRADPDSQ---ANRRLQAAGQAVRNAAERLVQSAQQEMIAr-----D 2500 nematode
P0CE95    2371 AT----GKAEEEELIATARSVAAATALLVSASRAKSGDDYQsqaAHSHLSTAARQVASATSDLVAAAKAATIFd----EQ 2442 Dictyostelium di...
XP_715249 1008 EKENIDLTKLTPYEGKTLEMEQQVKILKLENSILAARKRLAEIRKQEYKTP 1058 Candida albicans SC5314
AAC33564   920 ETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELA 970  human
NP_594069 1040 EVQHEDFSSLGVHEYRRKEIEQQVQILKLENDLVAARRRLFDMRKTSYHVA 1090 Schizosaccharomyces pombe 972h-
BAA31630   977 DRDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERMRLGELRKQHYVLA 1027 human
S44664     864 DEGSLDFSYLSLHAAKKEEMESQVKMLELEQSLNQERAKLAALRKQHYHMA 914  nematode
AAC83184   993 LDEKVDYAALSKHEFKTTEMEQQVEILKLENDLQGARKRLGQMRKVAYLHQ 1043 Yarrowia lipolytica
EDN62582   913 QQQPLDFT--SEHTLKTAEMEQQVEILKLEQSLSNARKRLGEIRRHAYYNQ 961  Saccharomyces cerevisiae YJM789
EDL98751  2519 QENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQQYKFl 2569 Norway rat
BAA75511  2410 PEVEFDTTNLSNAQIISKEMDQQIQILKLKKELEQAEKKLFSIRKKEYSDQ 2460 Dictyostelium discoideum
NP_490886 2501 DRNIAISD--RLVNGIAQVMDAQEEVLRKERELGEARHKLAHLNKARYERD 2549 nematode
P0CE95    2443 QQEEE-QEQFNFTGSKVKELEQQMKILKLEKELETARRQMLNSRKQNYNKN 2492 Dictyostelium discoideum
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