4B2T,3P9D


Conserved Protein Domain Family
chap_CCT_zeta

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TIGR02347: chap_CCT_zeta 
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T-complex protein 1, zeta subunit
Members of this family, all eukaryotic, are part of the group II chaperonin complex called CCT (chaperonin containing TCP-1) or TRiC. The archaeal equivalent group II chaperonin is often called the thermosome. Both are somewhat related to the group I chaperonin of bacterial, GroEL/GroES. This family consists exclusively of the CCT zeta chain (part of a paralogous family) from animals, plants, fungi, and other eukaryotes.
Statistics
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PSSM-Id: 274088
Aligned: 9 rows
Threshold Bit Score: 899.483
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4B2T_Z     3 AVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82  cattle
P40227     3 AVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82  human
P46550     3 SIQCLNPKAELARHAAALELNISGARGLQDVMRSNLGPKGTLKMLVSGAGDIKLTKDGNVLLHEMAIQHPTASMIAKAST 82  Caenorhabditis elegans
AAP68332   2 SVRVLNPNAEVLNKSAALHMTINAAKGLQDVLKSNLGPKGTIKMLVGGSGDIKLTKDGNTLLKEMQIQNPTAIMIARTAV 81  thale cress
P39079     2 SLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLKMLVDGAGNIKLTKDGKVLLTEMQIQSPTAVLIARAAA 81  Saccharomyces cerev...
AAG18499   3 AVSQLNSQAELYRHNQALSMNLNASHSLADILKTNLGPCGTLKMLVGGAGDVQLTKDGTVLLKNLTIIHPTAIMISRAAA 82  Trichomonas vaginalis
AAG01041   3 ALKILNQNSEASRRDQSLMMNMHAARSLEAILKTNLGPKGTLKMLVSGSGGIKLTKDGRVLLNEMHIQHPTANLIARAAT 82  Entamoeba histolytica
CAG25329   2 SIHLLNKKADSLRSTNVLMTNMNASKGMYEIIKSNLGPKGSYKMLVSSSGAIKITKDGNVLLNEMMIQHPTASMLSRICS 81  Plasmodium falcipar...
3P9D_F     2 SLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLKMLVDGAGNIKLTKDGKVLLTEMQIQSPTAVLIARAAA 81  Saccharomyces cerev...
4B2T_Z    83 AQDDITGDGTTSNVLIIGELLKQADLYIS-EGLHPRIITEGFEAAKEKALQFLEQVk--vSKE--MDRETLIDVARTSLR 157 cattle
P40227    83 AQDDITGDGTTSNVLIIGELLKQADLYIS-EGLHPRIITEGFEAAKEKALQFLEEV----KVSreMDRETLIDVARTSLR 157 human
P46550    83 AQDDVTGDGTTSTVLLIGELLKQAESLVL-EGLHPRIVTEGFEWANTKTLELLEKF----KKEapVERDLLVEVCRTALR 157 Caenorhabditis elegans
AAP68332  82 AQDDISGDGTTSTVIFIGELMKQSERCID-EGMHPRVLVDGFEIAKRATLQFLDNFktpvVMGdeVDKEILKMVARTTLR 160 thale cress
P39079    82 AQDEITGDGTTTVVCLVGELLRQAHRFIQ-EGVHPRIITDGFEIARKESMKFLDEFki-sKTNlsNDREFLLQVARSSLL 159 Saccharomyces cerev...
AAG18499  83 AQDENTGDGTTSTIILIDAMLKQCERRLA-EGVHPRVLTTGLEDARDEALRFIEKFk---tTPk-VDRDFLLNVARTSLC 157 Trichomonas vaginalis
AAG01041  83 SQDDIVGDGTTSTVLLCGEIMKLCEPYLN-EGIHPRLLVEGIELARQHLFDYLPKVv---KKIdcNDQLVLEHAVKSVIG 158 Entamoeba histolytica
CAG25329  82 SIDETLGDGSSSNLIVATSLIYLSEKYILyENIHPRIITQGFDIAKGILLEFLDSMkipvNIEenFDKELLYNVCKTCIR 161 Plasmodium falcipar...
3P9D_F    82 AQDEITGDGTTTVVCLVGELLRQAHRFIQ-EGVHPRIITDGFEIARKESMKFLDEFki-sKTNlsNDREFLLQVARSSLL 159 Saccharomyces cerev...
4B2T_Z   158 TKVHAELADVLTEAVVDSILAIKKQDEP-IDLFMVEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVS 236 cattle
P40227   158 TKVHAELADVLTEAVVDSILAIKKQDEP-IDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVS 236 human
P46550   158 TKLHQKLADHITECVVDAVLAIRRDGEE-PDLHMVEKMEMHHDSDMDTTLVRGLVLDHGARHPDMPRHVKDAYILTCNVS 236 Caenorhabditis elegans
AAP68332 161 TKLYEGLADQLTDIVVNSVLCIRKPEEA-IDLFMVEIMHMRHKFDVDTRLVEGLVLDHGSRHPDMKRRAENCHILTCNVS 239 thale cress
P39079   160 TKVDADLTEVLTPIVTDAVLSVYDAQADnLDLHMVEIMQMQHLSPKDTTFIKGLVLDHGGRHPDMPTRVKNAYVLILNVS 239 Saccharomyces cerev...
AAG18499 158 TKLPPELIDQLTEIVTDAVLAIKRDGEK-VNLFMVEQLTMMSKLASDTALIRGLVLDHGFRHPSMKRDMHNVYILTCNVS 236 Trichomonas vaginalis
AAG01041 159 TKITIDFVDQLSKMIVDAVKLIKIDNT--IDLFMVEIQSMKHKFATNTELIKGLVMDHGTRHPGMPHDIRNVFVLTCNVS 236 Entamoeba histolytica
CAG25329 162 TKLPICLADKLADDLVESIKIIYKPTKQ-IDLHMIEIMDIKRNMSINTKLVRGMVLDHGCRHPNMPNKLTKCFILVLNVS 240 Plasmodium falcipar...
3P9D_F   160 TKVDADLTEVLTPIVTDAVLSVYDAQADnLDLHMVEIMQMQHLSPKDTTFIKGLVLDHGGRHPDMPTRVKNAYVLILNVS 239 Saccharomyces cerev...
4B2T_Z   237 LEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKKKVCGDS----DK--GFVVINQKGIDPFSLDALAKEGI 310 cattle
P40227   237 LEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDS----DK--GFVVINQKGIDPFSLDALSKEGI 310 human
P46550   237 LEYEKTEVNSGLFYKTAKEREALLAAEREFITRRVHKIIELKKKVIDNSpdgkNK--GFVVINQKGIDPPSLDLLASEGI 314 Caenorhabditis elegans
AAP68332 240 LEYEKSEINAGFFYSNAEQREAMVTAERRSVDERVKKIIELKKKVCGDN----D---NFVVINQKGIDPPSLDLLAREGI 312 thale cress
P39079   240 LEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKKIIDLKNEVCGMDp---DK--GFVIINQKGIDPMSLDVFAKHNI 314 Saccharomyces cerev...
AAG18499 237 LEFENTEVNTQFASNAADMREKMAEAERKFVDARVQKIIDLKNKVCTNG----E---DFLVANMKGIDLPSLEKLQRAGI 309 Trichomonas vaginalis
AAG01041 237 MEYEKSEVNSSVCYSDVTQRTEMVKNERKYADDQVAKIVDLKRRLVEKYg--eDV--GLLVVNQKGIDQPSLDKLAAAKV 312 Entamoeba histolytica
CAG25329 241 LEYEKSEVFSSFVYSNAEDRDKLVESERKFTDDKVKKIIELKKILVEKKfketNEiyNFAVFNQKGIDPISLDLLAKENI 320 Plasmodium falcipar...
3P9D_F   240 LEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKKIIDLKNEVCGMDp---DK--GFVIINQKGIDPMSLDVFAKHNI 314 Saccharomyces cerev...
4B2T_Z   311 IALRRAKRRNMERLTLACGGIALNSLDDLNP-DCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKD 389 cattle
P40227   311 VALRRAKRRNMERLTLACGGVALNSFDDLSP-DCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKD 389 human
P46550   315 LALRRAKRRNMERLQLAVGGEAVNSVDDLTP-EDLGWAGLVYEHSLGEEKYTFIEECRAPKSVTLLIKGPNKHTITQIKD 393 Caenorhabditis elegans
AAP68332 313 IGLRRAKRRNMERLVLACGGEAVNSVDDLTP-ESLGWAGLVYEHVLGEEKYTFVEQVKNPNSCTILIKGPNDHTIAQIKD 391 thale cress
P39079   315 LALRRAKRRNMERLQLVTGGEAQNSVEDLSP-QILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGSTHYALAQTKD 393 Saccharomyces cerev...
AAG18499 310 SAVRRAKLRNMERLTLACGGRQMNSVENLEP-DCLGWAGHVYETIVGEDHWTFIEDVKAPRSVTILMRGPNNHTLKQMQD 388 Trichomonas vaginalis
AAG01041 313 MGLRRAKRRNMERLTLACGGVALNSFENEIPfECLGHAGHVYETVIGEEKYTFVEECEHPKSCTILIRGSDDQEIEQIKD 392 Entamoeba histolytica
CAG25329 321 MALRRIKRRNLERIVLCCGGNPCNNVYDLTE-EDVGYAGLVYEISINDEKYTFIEEVQNPKSCTIFIQAPNDYTIKQIKD 399 Plasmodium falcipar...
3P9D_F   315 LALRRAKRRNMERLQLVTGGEAQNSVEDLSP-QILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGSTHYALAQTKD 393 Saccharomyces cerev...
4B2T_Z   390 AIRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALV---KYKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKV 466 cattle
P40227   390 AVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALI---KHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKI 466 human
P46550   394 AIHDGLRAVFNTIVDKAVLPGAAAFEIAAYVMLK---KDVENLKGRAKLGAEAFAQALLVIPKTLAVNGGYDAQETLVKL 470 Caenorhabditis elegans
AAP68332 392 AVRDGLRSVKNTIEDECVVLGAGAFEVAARQHLLn--EVKKTVQGRAQLGVEAFANALLVVPKTLAENAGLDTQDVIISL 469 thale cress
P39079   394 AVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRsanMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMV 473 Saccharomyces cerev...
AAG18499 389 AVRDGLRAVNNAIEDACAIAGAGAFEAALCAHLH---EYKKSVSGKNRLGIEAFAEALLEIPRVLAQNAGHDAVDCLVAL 465 Trichomonas vaginalis
AAG01041 393 TIRDGLRACKNAMEDGGIVLGAGAFELQCWKELK---EFAKSVKGKAKLGVEVMGNAMLIIPKTLIENSGYDVIERLYEL 469 Entamoeba histolytica
CAG25329 400 AIRDGLRSIKNVIDDKCVLSGAGSFEIMAYCKLK---DEEKKIKGKQKFALDIYANSLLNIPKVLLENSGLDIHQTLFNV 476 Plasmodium falcipar...
3P9D_F   394 AVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRsanMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMV 473 Saccharomyces cerev...
4B2T_Z   467 QAEHSESG-----QLVGVDLNTGEPMVAAEAGIWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530 cattle
P40227   467 QAEHSESG-----QLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530 human
P46550   471 IEEKTAAG-----PDIAVGLDLETGGAVEPQGIWDNVTVKKNSISSATVLACNLLLVDEVMRAGMTNLK 534 Caenorhabditis elegans
AAP68332 470 TSEHDKG------NVVGLNLQDGEPIDPQLAGIFDNYSVKRQLINSGPVIASQLLLVDEVIRAGRNMRK 532 thale cress
P39079   474 EDELDDAQdsdetRYVGVDLNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRSTLK 542 Saccharomyces cerevisiae S288c
AAG18499 466 QAAADKG------EVKGIDLETGELLDPKEKGIWDNYSVKRQQLQSAPLVATQLLLVDEVLRAGVQMRK 528 Trichomonas vaginalis
AAG01041 470 EDNILEG------KIGGVDIETG--AFKEIDDIWDGIRVKKQMIQLASVLASQLMLIDVVMRCGSAKNR 530 Entamoeba histolytica
CAG25329 477 IDKYNEDRs----EPLGLDLDTGEPIIAHLKGIYDNYCVKKEILSIATAISQQILLVDEIIRAGKSMGE 541 Plasmodium falciparum 3D7
3P9D_F   474 EDELDDAQdsdetRYVGVDLNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRSTLK 542 Saccharomyces cerevisiae S288c
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