5T5S,2ZVF,6TVV,5O1U,5CET,5IZO


Conserved Protein Domain Family
DHHA1
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pfam02272: DHHA1 
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DHHA1 domain
This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Links
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Statistics
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PSSM-Id: 396724
Aligned: 120 rows
Threshold Bit Score: 34.3397
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5T5S_A  62 KDELRETLKSLKKVMddLDRASKADVQKRVLEKTKQFIds-npNQPLVILEMeSGATAKALNEALKLFKMh----sPQ-T 135 human
Q9WZH4 159 AKFLLENGANLDEVAlyTREELTPRQMELLDDLIENARdyevnGVPITISMIeCEDFVGGLGLIVSKAWEm----mGK-E 233 Thermotoga maritima
O26266 318 LRDHRTYLAVTLDEI--MDEELIR-------------------DMENLQYFHaPGVNTAVVGTVAGMLLGy-----GDwR 371 Methanothermobacter t...
Q58387 341 LRKHRNNLREALEH---VKNDVEIIQKDRFQYFE---------TDKIMSNIV------GIVAGMSYSIEE------VDwM 396 Methanocaldococcus ja...
O57804 334 VEEYKKEQIEARKWL--LQNWEKEVWE----------------GENVYILYVgKNIRDTLVGIAASMAINagl-anPEkP 394 Pyrococcus horikoshii
O27473 324 QKNYREELVKGLAWI--RREGSTTL------------------ENLQYIYSE-DKAFKGIMGTIASISLSlk---iLD-P 378 Methanothermobacter t...
Q9HMY2 335 ARSLREEHRQT------LSEGVSWVTREGVTVE----------DDLQWFHAD-DRIRETIVGIVAGMALSgdetenDR-P 396 Halobacterium salinarum
Q979X8 351 MANHRKNLVNGYNQI--LSKGLKSLKNVDYF-------------------YAgKDINENIVGIIANMVLAkt--geTMrP 407 Thermoplasma volcanium
Q9HKR9 353 MASHRRKLVNGYNHI--MAEGIKSLNNIDYF-------------------YAgKDINENIVGIIANMILArd--pdTVrP 409 Thermoplasma acidophilum
Q9UYJ6 196 VAPVSDENVEQSKRIa-VLKACQRMEIHKVR------------KFIIVTSKV------SAYEALACKVFL------QLgA 250 Pyrococcus abyssi

5T5S_A 136 SAMLFTVDNEAgKITCLCQVPQNaa-nRGLKASEWVQQvsglmdGKGGGKdVSAQATGKNVGC-LQEALQLATSFA 209 human
Q9WZH4 234 TFIAIVKMGK--KIYVIGRTSSP----D-VDLGSLMKDl----gGGGHTRaASATITGKEIDEvLKEVLNRLHDHV 298 Thermotoga maritima
O26266 372 RPMIGLGETADg-LKVSLRCSRLla-fDGIHFGSIMRRvaekvgGSGGGH-ATACGAYIPSER-EREFLELLDRAI 443 Methanothermobacter therm...
Q58387 397 KPIFAITEDENg-YKVSARCPKLlcfaEDVNLAKAIKYasekvnGSGGGH-KFACGAYIPDNK--REFIKYLEIAL 468 Methanocaldococcus jannas...
O57804 395 VIVFADTDEDPnLIKGSARTTEKal-eRGYHLGEALRKaaeiigGEGGGH-AIAAGIRVPKAR-FAEFRKLIDKLL 467 Pyrococcus horikoshii
O27473 379 DIPLLGLSRMDqHVKVSARTTRPav-eRGVNLGVALRDaaasfgGTGGGH-DIAAGAMVPYRD-MESFLQLVDEIL 451 Methanothermobacter therm...
Q9HMY2 397 IVAFAAKDDEP-AVKVSARATARvv-dAGVDLAVVVREaaaaagGDGGGH-EAAAGATVPAGN-ERAFLDAASGVL 468 Halobacterium salinarum
Q979X8 408 LVTMADSDPG--TIKISVRAGKSfl-sSGIDLADLFRRaavktgGVGGGH-DLAAGANIPADR-MGDFLKFIDEEI 478 Thermoplasma volcanium
Q9HKR9 410 LITMADSDPG--TVKASVRANKTfl-kIGIDLADLFRRaaatvgGVGGGH-DLAAGANIPAGR-MNDFLNFIDLEI 480 Thermoplasma acidophilum
Q9UYJ6 251 DVAIVGSEKD--GVRISARAKDYlv-kKGLHLGKLMEKvgpiigGSGGGH-PGAAGANG-KEN-LDEAIKFLVKEV 320 Pyrococcus abyssi
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