Conserved Protein Domain Family
grpIintron_endo

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TIGR01453: grpIintron_endo 
group I intron endonuclease
This model represents one subfamily of endonucleases containing the endo/excinuclease amino terminal domain, pfam01541 at its amino end. A distinct subfamily includes excinuclease abc subunit c (uvrC). Members of pfam01541 are often termed GIY-YIG endonucleases after conserved motifs near the amino end. This subfamily in this model is found in open reading frames of group I introns in both phage and mitochondria. The closely related endonucleases of phage T4: segA, segB, segC, segD and segE, score below the trusted cutoff for the family.
Statistics
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PSSM-Id: 273636
Aligned: 15 rows
Threshold Bit Score: 134.821
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAK84266  90 KGGFYWIFNN-VNGKHYVGSS--VLFERRIFEYLKPsYLKKKssqnsLISKAMIKHGYSNFVIVILEI--Ygd--qsLCL 162 Rhizophydium sp. 136
AAC49244  73 KAGIYGIINN-KTNKIYIGSA--VNLHKRLVEHLYS-DKTNI-----RLQRSIGKDGLSSFSFIIFEY--HdfndsiLEF 141 Allomyces macrogynus
CAA73995 112 RSGIYGWYCI-PLKKIYVGSA--QDLSVRALGHMTMpERSNK-----NLQDAVAKYGWESFVFIVFAF--Gnts-kiVTA 180 Chlorogonium elongatum
CAA69145  71 KSGVYLVRND-INGNCYVGSAasNRINVRFRNHCIHlNNTNV-----RLSRAINKYGLHNFSFHILEY--YsgfvhkENL 142 Chlorogonium elongatum
CAB72450 107 KSGIYLWTNK-INGKRYVGSR--LDLRKRLLNYFNSsYLLDRkd-imIIYKALLAHGFENFTLEILEY---------CEA 173 Podospora curvicolla
CAA38804  71 KSGIYKWTNK-LTNDIYIGQS--VDLSKRFIRYFNMsYLKNRet--lIISRALIKYGYSNFQLEVLEY---------CDI 136 Podospora anserina
CAA38774  44 KAGIYRWINN-NNGKCYVGSC--VDLSKRLYRYYSLaHITQQsk-fsLICKALLKRGYSSFTFEILEY---------CNK 110 Podospora anserina
AAK84293   3 KSGIYKITYLpIKSFFYIGSS--KNLGKRFKYHYYItKKSST-----FLGLFLAIFGRENFSITVIEV---------CNK 66  Rhizophydium sp. 136
AAK84261  26 KSGVYIFVCL-INKKMYVGSS--INLKRRLKTHLAVhSKELRsn--iKLKNDKIKYGIKNFGFGILEY---------INT 91  Rhizophydium sp. 136
CAC51107   1 MKAVYKIRNI-KNGKFYIGSS--ANFRKRKTEHLRLlKSGSHhn--kPLQEDFNTYGENNFLFEVLYHsdY------INR 69  Bacillus sp. BSG40
AAK84266 163 SDYKTKfidrED-ALIKIVKN---FGn-CYNIQDFSSrvrRPA-----GYTFSDETKLKMSEVWDEErkknlisrsslpk 232 Rhizophydium sp. 136
AAC49244 142 IDFNDLllesET-FYIQSINP---DF--LYNFKLHAT---SSA-----GYKHTDEAKAKMSARMAGE------------- 194 Allomyces macrogynus
CAA73995 181 EQLIEL----EN-LFLKIFPA---DF--KFNVLTEAY---SSI-----GFKHSEETKRLLSELRRGKplsdetkt----- 237 Chlorogonium elongatum
CAA69145 143 SSNHLSllalET-SYINKLDP-------VYNILTVAG---SSL-----GYKHTVETRNKMKVNFSQErk----------- 195 Chlorogonium elongatum
CAB72450 174 SVLIER----EQ-YYIDLLNP-------EYNILKIAG---SRL-----GAKHTLEAIAKI-------------------- 213 Podospora curvicolla
CAA38804 137 ADLTER----EQ-YYLDKLNP-------KYNILKIAG---SSL-----GHKLTEETKAKISKSLKGIyv----------- 185 Podospora anserina
CAA38774 111 EDVLIR----EQ-YYLDLLKP-------EYNILKIAG---SPL-----GYKHTEEDKEKM-------------------- 150 Podospora anserina
AAK84293  67 DKLESR----EN-YYFKIFHP-------LLNILTEAKknaSRE-----NFGISPITKLKIS------------------- 110 Rhizophydium sp. 136
AAK84261  92 KDRKEIfyleQK-YLDELFKE---SKdlIYNISKDAIvtfATYn---kGKGKLRSRKGENNPMFGRIg------------ 152 Rhizophydium sp. 136
CAC51107  70 FDLYKK----EQeFLSNSEKEqlyNL--YDNAFGMSY---RGEknpmfGKTHSEAVRRNSSKINSGK------------- 127 Bacillus sp. BSG40
AAK84266 233 seetklkiieIRKLYLNK-IANDLDLKEFNRIkrSHKillyennvlvksfdslseaA-DKLHKNHKTINKHIKegtllk- 309 Rhizophydium sp. 136
AAC49244 195 ----------N-HPMFGK-SHTDEAKAKISDAniGEN-------------------N-PMFGKSHTDEAKAKIs------ 236 Allomyces macrogynus
CAA73995 238 --klsalhsgSNNPFFGK-KHSEEFKAWLSKErmGSK-------------------N-PMYGKQFSPEFLAQQt------ 288 Chlorogonium elongatum
CAA69145 196 --------dfIGNLNKGK-TAPEETRALMSLKakERYs------------------D-PVFKAEFLLKNKDN-------- 239 Chlorogonium elongatum
CAB72450 214 -----------KTGALNR-SKEALAKNLEHLKklNSS-------------------------QEHKEHLIKLNts----- 251 Podospora curvicolla
CAA38804 186 ---------gEKSALYGR-THSEETKALMALNklGAN-------------------N-SLFGKTHSEKTKELMgqkalgr 235 Podospora anserina
CAA38774 151 ------------RGPRSL-NPEHLAKIRSHISklN--------------------------------------------- 172 Podospora anserina
AAK84293 111 ------------KSLMGK-KHSLETRIKMSKNrsGIN-------------------H-HYYNKSLSKVTLDA-------- 149 Rhizophydium sp. 136
AAK84261 153 ----------KLNPQFGV-LPTNSIRVGLFDSl-DNLikefktkke--aytelkkdT-KDFNRLIEHKTILKIdgqlcyf 217 Rhizophydium sp. 136
CAC51107 128 -----------NNYWYDKpEHMEKMRSKITKRfdGRK-------------------HtEETKRKMSLSRKGRK------- 170 Bacillus sp. BSG40
AAK84266 310 ---dkyivKKEEGQsnlkIYKIGLFYSDGKLYT----E----FNTMADLVREYNSSHQTINKYIESGe-LWRDKYYIKR 376 Rhizophydium sp. 136
AAC49244 237 --------AKKSK------IRVLILDTQSNTVD----I----FDNTVLASEFIDVHKGTISKNIKSGr-LLYNRYLILK 292 Allomyces macrogynus
CAA73995 289 --------GYKTGGknpnAKGVKLLDTVNGTIK----Y----FDTTTQCAEYLKMHRSNLSNVLYGSg-LYKHYKVSFv 350 Chlorogonium elongatum
CAA69145 240 ----------FFKP-----APINLVDSDGKILA----S----FKSISAAAKHYGGCRKHLSQHVDKPnmKYKGLGYLKS 295 Chlorogonium elongatum
CAB72450 252 -------lEQIAKT----AHPVIVLNTLNGESF----E----FRSITQAAKFLAVHPEILRRHIVKEk-LYLDKYLIIK 310 Podospora curvicolla
CAA38804 236 khseetllKMSASR----GYLVNIYEKSDSKGF----QligsFVSIRRAAKFLGISSNTIRLYINSGk-IFKDRYKFTS 305 Podospora anserina
CAA38774 173 -----------AKR----AISFVVNDLEKKTLT----E----FSSLRAAARELHIAEVSIKKYLNNSk-LFKNRYIFTS 227 Podospora anserina
AAK84293 150 --------AAEVLG-----IKIYVYDAKTLTLV----Nnk-pFRSFRETEKNMPIGRKTIQKKLDTGk-PFKGFYYYTK 209 Rhizophydium sp. 136
AAK84261 218 kiknnpnnIPPTKSigrdKKAINVYDKNNNLLY----N----FESITETALKLNIPKSSIQRCQKSEs-LFKEKYFFKL 287 Rhizophydium sp. 136
CAC51107 171 --------KTKE-T----CLKLSLNNGNRVGIIvdgvY----YHSMSEAGRRLNISRNTINSRVNNSk--FKNYFRCSE 230 Bacillus sp. BSG40
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