Conserved Protein Domain Family
TRAP_alpha

?
pfam03896: TRAP_alpha 
Translocon-associated protein (TRAP), alpha subunit
The alpha-subunit of the TRAP complex (TRAP alpha) is a single-spanning membrane protein of the endoplasmic reticulum (ER) which is found in proximity of nascent polypeptide chains translocating across the membrane.
Statistics
?
PSSM-Id: 461085
Aligned: 19 rows
Threshold Bit Score: 338.22
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
EFA00653       8 SLLVFPAVIFTLdngLK--MVAHAEEDP---LEDE----------VEVEGeaDVEEVAPTDA----------EDEEDSE- 61 
6_pfamImport   6 FLLAIPALVLMQ---NKvtMAAGAEEDD---VDDEm---------VDVEG--EETAVTGEDAv---------EEEESQE- 58 
XP_015790503  11 LLLLIPLNLFs---pTIsfQGVDAADQK---NEPNag-------sDSVEG--EDEAAVEEDAggdalvsgtgEDEDDSL- 74 
XP_015220433  12 LLLAFPCSLIgs--vGRvsAESEPPGDGt----------------ADSVVdeEEEEDDEEALveethisddsGDEQDDPv 73 
XP_019214354  12 FLLAFPCGLis---vGHvyADSDSAEDI---VEDSda-------aVDe----EEDDEDVLVEedqiqtsdgdEDDSDEAa 74 
CAF96840      52 FLVAFPCGLvs---vGHvaADADSAEDV---ADDPea-------aVDe---eEDDEEDVLVEedqmrsterdDEDTDETd 115
XP_019853353  15 SLFLTPLLSLSGpslALadDAVVGEDDEvmsVDDEegeddenvvlPDAG---EARESGGDGAgsee---eeeEEEEEED- 87 
NP_001280344   1 ---mefkwmllclsllAvsTGVARAEDE---IDAD-----------------EEMIVSEDQGlvetegdestIEDLEPT- 56  pea aphid
XP_028430979  12 lllAFPCGLISI---GQvsADSDSAEDI---AEDPda-------aVDe----EEDDEEVLVEedqiqpsegeEEDSDEAa 74  yellow perch
XP_014342296     --------------------------------------------------------------------------------     coelacanth
EFA00653      62 --KTTASPDADTTLLFVrpi-ataSQLELPAGVPVEFLVGFRNKGKEDFVLESLEASFRYPMDFNFYIQNFSAIGYSKVV 138
6_pfamImport  59 --KPGGSPDADTTILFTkpaqlagTTLDLPGGVLVEFLVGFKNKGTQDFVLETLDASFRYPMDFNFYIQNFSTLAYERHV 136
XP_015790503  75 --SLKPSPDVDTYFMFTkp---agKGLELPANSDAHFLVGFANRGQKDFIVESMGASFRYAMDFNFHIQNFSAIPYNKVI 149
XP_015220433  74 eaTVTSHPDVDTTIIFV-------SGEEFPANEIVKFLVGFTNKGSQDFTVQSLEASFRYPQDYQFYIQNFTVLPLSTLV 146
XP_019214354  75 dkLLASHPDADTTIIFT-------TGEEFPANEIVRFLVGFSNKGSQEFTVQSLEASFRYPQDFQFFIQNFTALPLNTVV 147
CAF96840     116 ekTLSSHPDADTTIIFV-------TGEEFPANEIVKFLVGFTNKGSQDFTVRSLEASFRYPQDFQFYIQNFTALPLDTVV 188
XP_019853353  88 --LYKPSPDAKTDIIFTn-----rAENNFLAGQIVKSLIGFSNNGNENFIVTSVEASFRYPQDFSYFIQNFSKVYYDAYV 160
NP_001280344  57 --------DADTYLLFTkpvfeekASIELPAGRLSEFLVGFTNKGSNDLVLETLDASLRYPMDFNFHIQNFTTVLLEKTI 128 pea aphid
XP_028430979  75 dkLLTSHPDADTTILFM-------TGEEFPANEIVRFLVGFTNKGGQDFTVQSLEASFRYPQDFQFYIQNFTALPLSTVV 147 yellow perch
XP_014342296   1 -----------------malspsfslADFPANEIVRFLVGFTNKGSEEFLVKSLDASFRYPQDFQFYIQNFTALPLNTLV 63  coelacanth
EFA00653     139 QPEQEATLAYSFIPSEAFAGRPFGLNINLAYRDASGNSFQEAVYNETVQIIELEEGLDGETFFLYVFLVAGVVLLLVIGQ 218
6_pfamImport 137 KPKQEATLLYSFIPAEAFAGRPFGLSVNLRYRDLSGNQFYEGVYNETVNITELDEGLDGETFFLYVFLGACVVLLLVVGQ 216
XP_015790503 150 KPNEETTLAYSFFISEAYSTRPYGFTVELHYKDKDGNQFMNAVFNETVSIVEVDEGLDGETIFLYIFLIALVGLLAFGAQ 229
XP_015220433 147 QPQRQASFEYSFIPALPMAGRPFGLVILLNYQDSEGNVFQSAIFNQTVTITELEEGLDGETVFMYVFLSGLVALILFGLY 226
XP_019214354 148 KPQAQASFEYSFIPAQPMAGRPFGLVILLNYQDTEGSVFQTAVYNQTVTITEREEGLDGETMFMYVFLAGLVSLLLFGMY 227
CAF96840     189 QPKAQASFEYSFIPAQPMAGRPFGLVILLNYLDSEGGVFQTAVYNQTVTITETEEGLDGETMFMYIFLGGLVVLMLFGMY 268
XP_019853353 161 PPSHQASFTYDFTPSESFYSRPFGLVVNVYYKTEEGNEFRDAVFNGTVNIVEIEEEFDAESFFMYVLMISGVCLLMFIIH 240
NP_001280344 129 PPGSQATLGYAFIPADAFAGRPFGLSINLAYRDYEGKQMISKLYNDTVNIIEVEEGLDGETLFLYVLMAAACVLLLVGGQ 208 pea aphid
XP_028430979 148 QPQSQASFEYSFIPAQPMAGRPFGLVILLNYLDTEGNVFQTAIYNQTVTIIELEEGLDGETMFMYIFLVGLVALMLFGIY 227 yellow perch
XP_014342296  64 PPEKQASFEYSFILAEQMAGRPFGLVINLHYKDSNGNVFQNSVFNQTVMIREADEGLDGETVFMYVFLFAVVVLMLFGLY 143 coelacanth
EFA00653     219 QTLLSFGKK-RITRKaa--------pVETGTS-NP-NNVDYDWLPKQTLATLNKEks-qkSPKsikQSPRQRKVKRSTGS 286
6_pfamImport 217 QLLVSVGKR-RVTSSnassgshsrhkVETGTAgDK-NDVDYEWLPKETLQSLNKSprvnkSPK---TSPRARKAKRAAGD 291
XP_015790503 230 QLFFSMSKK-RISAPka--------kVEVGTV-ST-TDVDYDWLPPETLSAINK------SPRn-kASPRQRKVKRGTGS 291
XP_015220433 227 QVLESRTRK-RVPGK-----------VETGTG-GL-NDVDISWIPQETLNVMNKA-----SPK---ASPRKRT-KRAAGT 283
XP_019214354 228 QVLDSRTKK-RLSVK-----------IEKGTA-GI-NDVDISWIPQETLNVMNKA-----SPK---ASPRKRT-KRAAGT 284
CAF96840     269 QVLETRTRK-RIPLK-----------VEKGTG-GM-NDVDISWIPQETLNAMNKA-----SPK---ASPRKRA-KRAAGR 325
XP_019853353 241 FVWTTVKRGgRAAPKkra------apVERGTTkNKrSQVDESWLPEGTI---QKK-----SPRk-pTSPRNRQKTTsnnt 305
NP_001280344 209 QFLYSVSKK-RVGGGlpsr---tranLETGTK-TS-KQIDMDWVPKNVLNHLNKQk---------aQSPKQKRVKKtd-- 271 pea aphid
XP_028430979 228 QVLETRTKK-RIPVK-----------IEKGTG-GM-NDVDISWIPQETLNVMNKA-----SPK---ASPRKRT-NRAAGA 284 yellow perch
XP_014342296 144 QVLETRTRR-RAVQK-----------METGTA-SH-GDVDLSWLPRETLNMINKV-----SPK---PSPRKRT-KRTAGV 200 coelacanth
EFA00653     287 E 287
6_pfamImport 292 D 292
XP_015790503 292 s 292
XP_015220433 284 D 284
XP_019214354 285 D 285
CAF96840     326 D 326
XP_019853353 306 l 306
NP_001280344     -     pea aphid
XP_028430979 285 D 285 yellow perch
XP_014342296 201 D 201 coelacanth
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap