1OQK,6K0B,2KI7,1TSF


Conserved Protein Domain Family
RNase_P-MRP_p29

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pfam01868: RNase_P-MRP_p29 
Ribonuclease P/MRP, subunit p29
This family consists of several archaeal and eukaryotic proteins. The archaeal proteins are found to be expressed within ribosomal operons and several of the sequences are described as ribonuclease P protein subunit p29 proteins. The structure of the RNase P subunit, Rpp29, from Methanobacterium thermoautotrophicum has been determined. Mth Rpp29 is a member of the oligonucleotide/oligosaccharide binding fold family. It contains a structured beta-barrel core and unstructured N- and C-terminal extensions bearing several highly conserved amino acid residues that could be involved in RNA contacts in the protein-RNA complex. Rpp29 catalyzes the endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. It interacts with the Rpp25 and Pop5 subunits.
Statistics
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PSSM-Id: 460367
Aligned: 201 rows
Threshold Bit Score: 65.9083
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1OQK_A             9 RNIFRHELIGLSVRIARSVHRDIQGISGRVVDETRNTLRIE--M-DDGREITVPKGIAVFHFRTpqgelVEIDGRALVAR 85  Methanother...
jgi:Igag_0156      6 HNILFHELIGLDVTILSHSDPHLIGVSGRIVDETMNTLRIL--L-NNGRILTVFKRYGLFETTLpgntkMVIDGSQILGR 82 
CBRAS:FFONT_0512   4 SNITFGDLFGSEVEVLMYPDRNVIGLIGIVENETQKTISIY----RNEKTITLFKDYIVFKIRSkn-seTVIYGNEIVGR 78 
CBRAS:ASAC_0230    6 SNIRFRPLIGLKLKVISSTDPSLLGVSGTVVGDSKNALRLRveRgDRKKEITIIKLHSTFSITTpd-gdFIVRGLDIIGR 84 
CBRAS:TCELL_0334   6 KNILFHEIIGLRVRVLSYTDTNLNGLEGVVIDETLKTLLIE--T-AEGRRIRVFKPSGVFEFKLphgevVVIKGDLILGR 82 
A3DNB5             6 RNIFYHELIGLRIKIIEYPDKSLVGLTGLVIDETQKTLLIE--T-NSGRRVRVLKANGVFQFMLpnkekVIIRGVQILGR 82  Staphylothe...
B8D5W2             6 RNIAYHELIGLEVRILQYPDPSLVGLKGKVVDETLKTLVIE--T-PSGRRVRIFKFNSILEFMLpdgeaVVIKGSTIIGR 82  Desulfuroco...
WP_013129721       6 SNLVYHELIGLRARVIEYPDPSVKGFEGVVVDETLKTLVLD--N--GFRRIRVFKENGVFEFTLpdggsVVIKGFEILGR 81  Thermosphae...
A2BMC7             6 WNIVFHSLIGLRARVLATSDPGLRGLEGVVVEETRHSLVVE--T-RDGRRVRVLKANSIFLFQLpggswVVVRGEEIAGS 82  Hyperthermu...
jgi:Pyrfu_1666     6 WNIFFHVLVGLEVCVLSHPDPAMVGRCGVVIDETARTLVLR--D-KSGKVFRVTKRDAIFEFRVgr-vsVIAEGELIVGR 81 
1OQK_A            86 PEERIKK 92  Methanothermobacter thermautotrophicus
jgi:Igag_0156     83 PEDRLKR 89 
CBRAS:FFONT_0512  79 PEDRTKE 85 
CBRAS:ASAC_0230   85 PEERLKK 91 
CBRAS:TCELL_0334  83 PAERLKR 89 
A3DNB5            83 PEDRLKN 89  Staphylothermus marinus F1
B8D5W2            83 PWDRLKM 89  Desulfurococcus amylolyticus 1221n
WP_013129721      82 PWERVKM 88  Thermosphaera aggregans
A2BMC7            83 LAERVKR 89  Hyperthermus butylicus DSM 5456
jgi:Pyrfu_1666    82 VEERLKR 88 
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