3O7A


Conserved Protein Domain Family
PHD_PHF13
?
cd15632: PHD_PHF13 
Click on image for an interactive view with Cn3D
PHD finger found in PHD finger protein 13 (PHF13)
PHF13, also termed survival time-associated PHD finger protein in ovarian cancer 1 (SPOC1), is a novel plant homeodomain (PHD) finger-containing protein that shows strong expression in spermatogonia and ovarian cancer cells, modulates chromatin structure and mitotic chromosome condensation, and is important for proper cell division. It is also required for spermatogonial stem cell differentiation and sustained spermatogenesis. The overexpression of PHF13 associates with unresectable carcinomas and shorter survival in ovarian cancer.
Links
?
Statistics
?
PSSM-Id: 277102
Aligned: 4 rows
Threshold Bit Score: 83.1652
Created: 12-Aug-2013
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
Zn binding sitehistone H3
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C C H C C CClick to see conserved feature residue pattern help
Evidence:
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1           # #           #  #    #  #             #  # 
3O7A_A         4 LVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCR 50  human
NP_001088702 254 LVTCFCMKPFAGRPMIECNECNTWIHLSCAKIRKSNVPEIYVCQKCR 300 African clawed frog
CAF91049     221 LVTCFCMKPFAGRAMIECNKCHTWIHLSCAKIRKSHVPETYVCQRCR 267 spotted green pufferfish
NP_001274131 238 LVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVYICQKCR 284 chicken

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap