4CPC


Conserved Protein Domain Family
Cor1

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pfam04803: Cor1 
Cor1/Xlr/Xmr conserved region
Cor1 is a component of the chromosome core in the meiotic prophase chromosomes. Xlr is a lymphoid cell specific protein. Xlm is abundantly transcribed in testis in a tissue-specific and developmentally regulated manner. The protein is located in the nuclei of spermatocytes, early in the prophase of the first meiotic division, and later becomes concentrated in the XY nuclear subregion where it is in particular associated with the axes of sex chromosomes.
Statistics
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PSSM-Id: 461436
Aligned: 39 rows
Threshold Bit Score: 94.6058
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4CPC_A         20 KALLAKRKRLEmyTKASLKTSNQKIEHVWKTQQDQRQKLNQEYSQQFLTLFQQWDLDMQKAEEQEEKILNMFRQQQKILQ 99  
XP_001053430  117 KSHLAKRKQYCqdVKTSIDTLNEKLVRIFKTQQRERKMLRSKYSMMFEPLFQQWEKDVMKVGQEDDSFVNSSNQRAGTMY 196 
NP_001119789   76 ESHLAKKKQFCqdVVTSVKRLSEKLVSIYKRQKRERTMFHSNYSKSLQSLFQQWDMSVEKVGQEEDSFINSSHQHEKIIY 155 
Q99L59         70 KVLQENREKFSriMTSSFSAMEVKIKDVLKTQCEQRQKLCQDYSLQFTNLSRKLTSDAYKLKKQAETLSNMFMEQQKFIH 149  house mouse
XP_006229589   60 KSFNERKRRYVlnVSHTVQNIEWKIDHFLKLQHEQRQKLYQDYSHQFLTLAVMWNIDVEQVKKHAEKLSNILDEQQKLFQ 139 
XP_007605802   65 KPLHGRRKRYVlsVSNTIYNVEQRINHFLKLQHERRQEMYKEYSHQFLTLVVMWNIDVDQVKKHAENLSNILEEQQKLFQ 144 
NP_898917      60 KTLNERKRKYGvsVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQ 139 
XP_008247079   69 RVIYRKKQLFRrsVNASLRNIERIIVDSWKTRTEQRQAFYLRYSQQFLDALEDWDGNMQKTKQHESNMVKILELQQKVSQ 148 
XP_002591784 1371 KKKQHMKKQLDsfSRNTLKSTQKEVKGLWKGQMGRRMRVQEDFKGNLLHELDFLEKEMANLQACEEKALKFFENQQKLLS 1450
EDV21935       16 KSLNVKQKLLEefTLSSLSSSKKKVEETWIAHRRDRKELTENFEATVSNIMNSWKEEIQDSKRFEDKVHALLQQHQELLM 95  
4CPC_A        100 QSRIVQSQRLKTIKQLYEQFIKSMEELEKNHDNLLTGAQNEFKK 143 
XP_001053430  197 NAMMAQRATIDEAKTVSDQFLKNVQVLEDEHKVLDAIEQNKLEN 240 
NP_001119789  156 NTMMAQKATIDQAKAISDQFLKNIQELEEKHKLLDALEQNRLEN 199 
Q99L59        150 ETLTLQKNRMEEFKSLCEKYLEKLEVLRDSRGNSIAE---ELRR 190  house mouse
XP_006229589  140 QFQGIHMQKIEEFKELCDRHLKNLQAIKRCRRKAIVE---EARK 180 
XP_007605802  145 QFQVIHKEKIEEFKELCNRHLKSLQAIKSCRRKAIIE---EARK 185 
NP_898917     140 QFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIE---EARK 180 
XP_008247079  149 QAIKLRTKRLKELKTLYGNFLQSIKCLKERQIK-LANEQGGFTK 191 
XP_002591784 1451 TARITHEQRFRKIMHMEEDFHKTLTQLDREQEQ----QQISLRE 1490
EDV21935       96 EVRNLHAKYLTHLHESCKMYVDSISSIDERYEKRLASAHCAIKK 139 
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