6VRH,6ZBV


Conserved Protein Domain Family
SNF

?
pfam00209: SNF 
Sodium:neurotransmitter symporter family
These are twelve xTM-containing region transporters.
Statistics
?
PSSM-Id: 395155
Aligned: 17 rows
Threshold Bit Score: 563.451
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6VRH_A  79 RETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWrKICPIF 158
P27799  36 RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFTCGIPVFFLEVALGQYTSQGSVTAWrKICPLL 115 dog
P28571  86 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMF 164 house mouse
P28573  37 RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVW-KISPLF 115 Norway rat
Q03614  40 REQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFYMELCLGQYYRKGAITTWgRICPLF 119 Caenorhabditis elegans
P31652  79 RETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWrKICPIF 158 Norway rat
P23975  56 RETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVW-KICPFF 134 human
P27922  60 RETWSKKADFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLFFMVVAGVPLFYMELALGQFNREGAAGVW-KICPIL 138 cattle
P31662  60 RPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWhYVCPRL 139 Norway rat
Q08469  61 RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWnYISPKL 140 Norway rat
6VRH_A 159 KGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSC------KNSWNTGNCtnyfsedn--------------- 217
P27799 116 QGIGLASVVIESYLNIYYIIILAWALFYLFSSFTSELPWTTC------TNTWNTEHCmdflnhsgar------------- 176 dog
P28571 165 KGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYC------NNPWNTPDCagvldasnltngsrpaalsgnls 238 house mouse
P28573 116 KGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHC------GNWWNTERClehrgpkdgng------------ 177 Norway rat
Q03614 120 KGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFNLPWASC------NNSYNSPACyephwsedgtamc--------rs 185 Caenorhabditis elegans
P31652 159 KGIGYAICIIAFYIASYYNTIIAWALYYLISSLTDRLPWTSC------TNSWNTGNCtnyfaqdn--------------- 217 Norway rat
P23975 135 KGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDC------GHTWNSPNCtdpkllngsvl-----------g 197 human
P27922 139 RGVGYTAILISLYIGFFYNVIIAWALHYLLSSFTTELPWTHC------NHSWNSPRCsdarapnas-------------- 198 cattle
P31662 140 GGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECpvirngTVAVVEPECek--------------------- 198 Norway rat
Q08469 141 GGIGFASCVVCYFVALYYNVIIGWTLFYFSQSFQQPLPWDQCplvknaSHTYIEPECek--------------------- 199 Norway rat
6VRH_A 218 --itwtlhstSPAEEFYTRHVLQIH----------RskGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTA 285
P27799 177 -tatssenftSPVMEFWERRVLGIT----------S--GIHDLGALRWELALCLLLAWLICYFCIWKGVKTTGKVVYFTA 243 dog
P28571 239 hlfnytlqrtSPSEEYWRLYVLKLS----------D--DIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTA 306 house mouse
P28573 178 alplnlsstvSPSEEYWSRYVLHIQg--------sQ--GIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTA 247 Norway rat
Q03614 186 anqsvsaekiSAAEEYFYKGFLGLHeanapnshviR--SVTDLGNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTA 263 Caenorhabditis elegans
P31652 218 --itwtlhstSPAEEFYLRHVLQIHq--------sK--GLQDLGTISWQLTLCIVLIFTVIYFSIWKGVKTSGKVVWVTA 285 Norway rat
P23975 198 nhtkyskykfTPAAEFYERGVLHLHe--------sS--GIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITA 267 human
P27922 199 -sgpngtsrtTPAAEYFERGVLHLHe--------sQ--GIDDLGPPRWQLTSCLVLVIVLLYFSLWKGVKTSGKVVWITA 267 cattle
P31662 199 ---------sSATTYFWYREALDIS----------N--SISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSGKVMYFSS 257 Norway rat
Q08469 200 ---------sSATTYYWYREALAIS----------S--SISESGGLNWKMTGCLLAAWVMVCLAMIKGIQSSGKIMYFSS 258 Norway rat
6VRH_A 286 TFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTS 365
P27799 244 TFPYLMLVILLIRGITLPGAYQGVIYYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALC 323 dog
P28571 307 TFPYVVLTILFVRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIIS 386 house mouse
P28573 248 TFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVT 327 Norway rat
Q03614 264 LFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTS 343 Caenorhabditis elegans
P31652 286 TFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTS 365 Norway rat
P23975 268 TLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTS 347 human
P27922 268 TMPYVVLFALLLRGITLPGAVDAIRAYLSVDFHRLCEASVWIDAAIQICFSLGVGLGVLIAFSSYNKFTNNCYRDAIITT 347 cattle
P31662 258 LFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVS 337 Norway rat
Q08469 259 LFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLEMMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVS 338 Norway rat
6VRH_A 366 VVNCMTSFVSGFVIFTVLGYMAEMRNED-------------------------------------------VSEVAKDa- 401
P27799 324 FLNSATSFAAGFVVFSILGFMAQEQGLP-------------------------------------------ISEVAES-- 358 dog
P28571 387 ITNCATSVYAGFVIFSILGFMANHLGVD-------------------------------------------VSRVADH-- 421 house mouse
P28573 328 LGNAITSILAGFAIFSVLGYMSQELGVP-------------------------------------------VDQVAKA-- 362 Norway rat
Q03614 344 FINCATSFLSGFVIFSVLGYMSCKSGKP-------------------------------------------IEAVAQE-- 378 Caenorhabditis elegans
P31652 366 VVNCMTSFVSGFVIFTVLGYMAEMRNED-------------------------------------------VSEVAKDa- 401 Norway rat
P23975 348 SINCITSFVSGFAIFSILGYMAHEHKVN-------------------------------------------IEDVATE-- 382 human
P27922 348 SVNSLTSFSSGFVVFSFLGYMAQKHSVP-------------------------------------------IGDVAKD-- 382 cattle
P31662 338 FINFFTSVLATLVVFAVLGFKANIMNEKcvvenaekilgylnsnvlsrdlipphvnfshlttkdysemynvIMTVKEKqf 417 Norway rat
Q08469 339 FINFFTSVLATLVVFAVLGFKANIVNEKcisqnsemilkllktgnvswdviprhinlsavtaedyhvvydiIQKVKEEef 418 Norway rat
6VRH_A 402 -------------------GPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHvw--ak 460
P27799 359 -------------------GPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASMDMFPSqlrksg 419 dog
P28571 422 -------------------GPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNewi-lq 481 house mouse
P28573 363 -------------------GPGLAFVIYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYyl--rp 421 Norway rat
Q03614 379 -------------------GPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFPIlk---k 436 Caenorhabditis elegans
P31652 402 -------------------GPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHiw--ak 460 Norway rat
P23975 383 -------------------GAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVlk---r 440 human
P27922 383 -------------------GPGLIFIIYPEALATLPLSSVWAVVFFVMLLTLGIDSAMGGMESVITGLADEFQLlh---r 440 cattle
P31662 418 salgldpclledeldksvqGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKV------ 491 Norway rat
Q08469 419 avlhlkacqiedelnkavqGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPVVDTFKV------ 492 Norway rat
6VRH_A 461 RRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATG-PAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRI 539
P27799 420 RRELLILAIAVFCYLAGLFLVTEGGMYIFQLFDYYASSgICLLFLAMFEVICISWVYGADRFYDNIEDMIGYRPWPLVKI 499 dog
P28571 482 KKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQI 560 house mouse
P28573 422 KKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSAS-FGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRA 500 Norway rat
Q03614 437 NREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTT-WGLLIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRPGNYWKF 515 Caenorhabditis elegans
P31652 461 RREWFVLIVVITCVLGSLLTLTSGGAYVVTLLEEYATG-PAVLTVALIEAVAVSWFYGITQFCSDVKEMLGFSPGWFWRI 539 Norway rat
P23975 441 HRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAG-TSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRL 519 human
P27922 441 HRELFTLLVVLATFLLSLFCVTNGGIYVFTLLDHFAAG-TSILFGVLMEVIGVAWFYGVWQFSDDIKQMTGRRPSLYWRL 519 cattle
P31662 492 PKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSAT-LPLTVIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFY 570 Norway rat
Q08469 493 RKEILTVICCLLAFCIGLMFVQRSGNYFVTMFDDYSAT-LPLLIVVILENIAVSFVYGIDKFLEDLTDMLGFAPSKYYYY 571 Norway rat
6VRH_A 540 CWVAISPLFLLFIICSFLMSP--PQLRLFQ-YN----------YPYWSIILGYCIGTSSFICIPTYIAYRLI 598
P27799 500 SWLFLTPGLCLATFLFSLSQY--TPLKYNNiYV----------YPPWGYSIGWFLALSSMICVPLFVIITLL 559 dog
P28571 561 CWRFVSPAIIFFILIFTVIQY--RPITYNH-YQ----------YPGWAVAIGFLMALSSVICIPLYALFQLC 619 house mouse
P28573 501 CWLFLSPATLLALLVYSIVKY--QPSEYGS-YR----------FPAWAELLGILMGLLSCLMIPAGMLVAVL 559 Norway rat
Q03614 516 CWSCAAPFILLSMITSNFINY--QALTYQD-YT----------YPTAANVIGIIFALSGASFIPLVGIYKFV 574 Caenorhabditis elegans
P31652 540 CWVAISPLFLLFIICSFLMSP--PQLRLFQ-YN----------YPHWSIVLGYCIGMSSVICIPTYIIYRLI 598 Norway rat
P23975 520 CWKFVSPAFLLFVVVVSIINF--KPLTYDD-YI----------FPPWANWVGWGIALSSMVLVPIYVIYKFL 578 human
P27922 520 CWKFVSPCFLLFVVVVSIATF--RPPHYGA-YV----------FPEWATALGWAIAASSMSVVPIYAAYKLC 578 cattle
P31662 571 MWKFVSPLCMAVLTTASIIQLgvSPPGYSA-WIkeeaaerylyFPNWAMALLITLIAVATLPIPVVFILRHF 641 Norway rat
Q08469 572 MWKYISPLMLVTLLIASIVNMglSPPGYNA-WIkekaseeflsYPMWGMVVCFSLMVLAILPVPVVFVIRRC 642 Norway rat
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap