Conserved Protein Domain Family
Lipase_2

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pfam01674: Lipase_2 
Lipase (class 2)
This family consists of hypothetical C. elegans proteins and lipases. Lipases or triacylglycerol acylhydrolases hydrolyse ester bonds in triacylglycerol giving diacylglycerol, monoacylglycerol, glycerol and free fatty acids. Swiss:P37957 is an extracellular lipase from B. subtilis 168.
Statistics
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PSSM-Id: 396304
Aligned: 14 rows
Threshold Bit Score: 231.469
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q19310     42 KEPVIFIHGSGdtal-ftqQPLAtGFSRSIQYFLEQN-YTEAELYATTWGDTWGsGSMLDTYstihTCGNLIYLRRFLEA 119 Caenorhabditis ele...
O76556     63 QNPVIIVHGIT--------NKAS-RFGGTVAYLKSKG-YKNSEIYGTTWGDSGR-TPVGLVDm---KCNYVKQIRAMIIA 128 Caenorhabditis ele...
O62271     64 NQPLIIVHGVS--------DTAGeKPFWAAQWFRKEGkYAENEIYSTTYFNGAQgNPLKWIEys-mKCEYIKQVRSLIVA 134 Caenorhabditis ele...
Q19941     63 NDPVIFVHGVS--------DIAGgKMQALSATYKKHG-YGSGELYATTYDSGSKnNPIAWADys-lKCEHVKQIRTFILA 132 Caenorhabditis ele...
Q23548     63 DRPVVFVHGLN--------N-EAgSLWKIARDFTNAN-YPRQYLFATTWGKGTEpLNLNVAM----SCTHVQHVRRFIET 128 Caenorhabditis ele...
Q20437     67 NTPIVFIHGNSdsalkfgdGPFQsGWDEILKYFMSKD-YTLAELYGITYGDRNIsNSYIRHF----NCQNVQLHRRFLEF 141 Caenorhabditis ele...
O16380     83 KTPVIFIHGNSdsa--lktSSMAtGWDNTISYFSTQG-FTSAELYATSWQDTNSlKAETRTH----DCKDLTRLRKFFEA 155 Caenorhabditis ele...
Q22060     67 NTPVVFIHGNSdaal--hvssAAtGWSNSIEYFLEHG-YTVAELYATSWQDTNAlHAASRTH----NCKDLVRLRKFLEA 139 Caenorhabditis ele...
Q19462     62 GLPIVVIHGLA--------GYAGlSKKSLLNKYYSYG-QPKGTVFATTYARGKLmDSLQHGM----QCDYVLKVRTLILA 128 Caenorhabditis ele...
NP_493916  64 RVPIIIVHAGA--------SNAGvIQKYYRPQYIERG-YSDETVYTTTWGNTTD-TSQRNLEm---KCEYVKQIRRLILA 130 Caenorhabditis ele...
Q19310    120 VIGYTGAkKVDIIAHSVGVPLMRKVVKGGtlIGT-DGNCTLGPPLGAKVDTFLGIAGPNFGLCVCQLAQ----------T 188 Caenorhabditis ele...
O76556    129 VRQYTGQ-KVDVIGYSMGSPLARKAILGG--QCV-DTREILGAPLTELVDTFLSVAGANYGSVLCILPVp--------vG 196 Caenorhabditis ele...
O62271    135 VRLYTGR-NVDVIGFSLGVPVSRKAILGG--RCV-DTGEYLGEPLTRVVDTYIGVAGPNRGASPQLGPLsvpa---calS 207 Caenorhabditis ele...
Q19941    133 VKYYTQR-NVDVVAYSLGVPIARKAILGG--ECV-DTREDLGQPLTQYVDTFVGVAGPNHGISLQVAGVsipgcvigaiP 208 Caenorhabditis ele...
Q23548    129 VLKYTGAqKIDVIGYSMGSPIARKAILGG--KCVdNPNVALGPSLHSRVHTYISVAGANQGSQLCALP------------ 194 Caenorhabditis ele...
Q20437    142 VLHYTKAkQINIVAHSMGVSIARKAIQGGefVTK-TESCDIGPNLSHRIGTFIALASANYGMCPCQHa-----------F 209 Caenorhabditis ele...
O16380    156 VLAYTGYaKVSVISHSMGVTLGRKVIQGGivNGT-DGNCNLGVSISGKVDVFVGIAGANYGLCGCAGTVg---------L 225 Caenorhabditis ele...
Q22060    140 VLAYTAApKISVVTHSMGVTLARKIIKGGsvSAS-DGSCDLGLPLNKKVEVMIGISGANYGLCNCEG-Gs--------aT 209 Caenorhabditis ele...
Q19462    129 VHEYTQK-PVNIIACSMGSPITRKAILGG--HCV-DSGVNLGRPINHLIHNYVSVGGANHGAIMCAKQP----------F 194 Caenorhabditis ele...
NP_493916 131 VSNFTNN-QVDIVAHGEGSPIARKAVIGG--KCV-DTNEELGVPLTKSVRAFVSDKGINGGIPCDPKYD----------- 195 Caenorhabditis ele...
Q19310    189 VpawC-NALDGLYpgytCqdqlwcgyt---sgsckqenYSNLLQKTNDDPNRE-GDHVYAMWSDVDEVLLnrGMVWGKPT 263 Caenorhabditis ele...
O76556    197 T---C-NKKNGLH----C--------------------DSEFLQDINNQHRYE-GSHVFSIFSTADEKIG--FRSCGRPV 245 Caenorhabditis ele...
O62271    208 ItpiC-NSVNGLYsg-nCp------------------aQSEFLQDINKFAHYE-GQYTYSIYTQKDQMVG--YTVCGQLT 264 Caenorhabditis ele...
Q19941    209 IlpiC-SRVIGLYsg-lCp------------------tESDFLTDINEKNHYE-GKYVFTLYTETDEWIG--YKICDKIT 265 Caenorhabditis ele...
Q23548    195 FfdiC-NMKTGLM----C--------------------NSKFLEDINWFKNYEgSYKAFNLASTADFVVG--YMACGKKA 247 Caenorhabditis ele...
Q20437    210 AfpaC-GMETGFFpg-tCpemtcssqdvnisetcgevpYSNYLMNLNNSGKKD-ASFVASLWSDDDEILGkgNMVWGRQT 286 Caenorhabditis ele...
O16380    226 FaptC-NKKNGFWpgdsCggytssfcgysstpcngiskYSNLLNDMNNSNKKE-ASYIFSTWSKADDLIGnsDIVWGRPT 303 Caenorhabditis ele...
Q22060    210 LektC-NRVNGLWpgdsCglnyldcgltplpwpcsgvnYSSFLMQLNADKNKE-GDYVFSMWSLSDDLIEygTQVWGRST 287 Caenorhabditis ele...
Q19462    195 VngiC-SLTHGLD----C--------------------RSKFLQEINSQPFQY-GKNMFAIYSVADEVIGl-RNTCGEMS 247 Caenorhabditis ele...
NP_493916 196 TrrtClNMDIGLN----C--------------------ASKFMKDINAKGK---REAVHSIHSLAQLRPWanKMNCGLDV 248 Caenorhabditis ele...
Q19310    264 ARIPGMNGRWISDRNGHVAMKDLTELRQFE 293 Caenorhabditis elegans
O76556    246 SPIRGGTGFVKRDGLNHDQLMDTTHPLQRN 275 Caenorhabditis elegans
O62271    265 SPLPGQNGQRVYTDKNHDQVFDDTHEVQLR 294 Caenorhabditis elegans
Q19941    266 ARIPGEDGHRIYKKYSHDEIILRTCDTQIE 295 Caenorhabditis elegans
Q23548    248 SEFTGAHEWK-VEGRNHEQTEFDTAAIQLQ 276 Caenorhabditis elegans
Q20437    287 SLVPHSDMRKIYSDLKHNDVKLLTAEDQYN 316 Caenorhabditis elegans
O16380    304 SLIPLSDGKIIYEKLTHMQSKENTAIDQYK 333 Caenorhabditis elegans
Q22060    288 CFIPTSDGKVVYHVYTHMETKELTYVDQYQ 317 Caenorhabditis elegans
Q19462    248 SPLEGATSIV-KTRLMHGAVIGGTTEDQWR 276 Caenorhabditis elegans
NP_493916 249 YLIPDSKVFR-YDYNGIEENVHRVVEILKN 277 Caenorhabditis elegans
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