Conserved Protein Domain Family
GGN

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pfam15685: GGN 
Gametogenetin
GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.
Statistics
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PSSM-Id: 434857
Aligned: 2 rows
Threshold Bit Score: 666.085
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_005340572   2 GNVQSEPSAGGGSRKEqASDRASDSRRTSLVEPEVTPSSPAMRLARGLGVWFPGSSAPPGLLVPPEPQASPSPLPLTLEL 81 
EHA98176       2 GNVQSERSVGAGSQKE-ALNHTSDSRRTSLVQPEVTSSSPATRPAQGLGVWFPGSSAPPGLLVTPEPQASPSPLPLTLEL 80 
XP_005340572  82 PLPVTPPPEEAaaAAVSTPPPPPVGTLLPAPSKWRKPTGTAVPRIRGLLEASHRGQGDPPSLRP-LPPLPRQLTEKDPVP 160
EHA98176      81 PSPVTPPPEEA--AAVSTAPPPAVGSLLPTPSKWRKPTSTRVARIRGLLEASHSGQGDPLSVRPlLPLLPRQLIEKDPAP 158
XP_005340572 161 RAPApPPPTPLEPRKPPPLPPSDRQPPNRRITPALATSATSPTESQARHIGEGQTAGGACGGAPPQAGEGEMARSAASES 240
EHA98176     159 GAPV-PPPTPLEPRKPPPPPPSDRQPRSRGITPALATSATSPTDSQAKLSAEGKTARGVRKGSPPQAGEGEMARFSASES 237
XP_005340572 241 GLSLLCKVTFKSAPPLCPAAASGPLATKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARTLGEVPRAAQETEGGNG 320
EHA98176     238 GLSLLCKVTFKSRAPLSPAAASGPLTAKASLRGGRGRGLLATSSAISCTQVLKQGPLAPGAPRPPGEVPRGALETEGGEG 317
XP_005340572 321 DGEGCSGPPAAPASHARALPPPPYTTFPGSKPKFDWVSPPDGPERHFRFNGAGGGVGAPRRRAAALSGPWGSPPPPPGQA 400
EHA98176     318 EGEGCSGGPLAPESHTRALPPPAYTTFPGSKPKFDWVSPPEGPERHFRFNGAGGGIGAPRRRPAALSGPWGSPPPPRGKK 397
XP_005340572 401 HPTPGPRRPAPALLAPPMfifpaptngepvrpgPPGPQQLlprpppptppatpppVPPPTPQSPVLQPTPLPVARPPT-- 478
EHA98176     398 HPIPGPRRPAPALLAPPM---------------PPATRAL---------------VSPPIPRLPAPQQMPMAAVRPPTpr 447
XP_005340572 479 PCSGHVESALAPAPVPVMPPALAAEQAQAP----AQAPSPAPAPITADPSPPAPPPIKARTRRNKGPRAARGVTREDGAP 554
EHA98176     448 PGPGPGESVVVPDPTAPLPPTLAADQDPAPalaaAPSPSPSPAPATTEPLPPAPAPTKTRTRKNKGSRSARGATREDRLP 527
XP_005340572 555 GDGPRERtaaTVTDSSgggGGGSGALTAGAASSGAARHWPPFQVLNSCPCKCYCRHQPRHRRLPRNVSAWLSTPTNHLSE 634
EHA98176     528 GVGPRQK---TVTDSR---VGGSGAAPARAANTSAVRHWPPFQVLNSCSCKCYCRHQPHHRRLPSNVSAWLDTTTNHLSE 601
XP_005340572 635 PPWVATIKLAGSLVAGLEHYDLQATHPN 662
EHA98176     602 PPWVTTIKLAGSLVAGLEHYDLQATHSD 629
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