Conserved Protein Domain Family
2A0113

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TIGR00892: 2A0113 
monocarboxylate transporter 1
[Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Statistics
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PSSM-Id: 273325
Aligned: 7 rows
Threshold Bit Score: 646.799
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAB61338   1 MGRAD-------PEEGqlpapvkPPDGGWGWIVLFGCFVITGFSYAFPKAVSVYFKELMKDFHVGYSDTAWISSIMLAML 73  chicken
AAC18120   1 MGAGG-------PRRGa-----gPPDGGWGWVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAML 68  Norway rat
P53988     1 MPSETa-----vPPPHp-----iPPDGGWGWVVVGAAFISIGFSYAFPKAVTVFFKDIQQIFQASYSEIAWISSIMLAVM 70  golden hamster
Q63344     1 MPSESsvkataaPPPFp-----lPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSSQIAWISSIMLAVM 75  Norway rat
AAC70919   1 MPPMPs-----aPPVHp------PPDGGWGWIVVGATFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVM 69  human
AAB65515   1 MPPAIg-----gPVGYt------PPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVM 69  Trypanosoma cruzi
O15375     1 MPQAL---------ER--------ADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVL 63  human
AAB61338  74 YGTGPVCSIMVNQFGCRPVMLIGGLLASSGMILASFTTNIIELYLTAGVLTGLGMALNFQPSLIMLGTYFDKRRPLANGL 153 chicken
AAC18120  69 YGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGL 148 Norway rat
P53988    71 YAGGPISSVLVNNYGSRPVVIIGGLLCCTGMILASFSNSVLELYLTIGFIGGLGLAFNLQPALTIIGKYFYRRRPMANGL 150 golden hamster
Q63344    76 YAGGPISSVLVNNYGSRPVLIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRKRPLANGF 155 Norway rat
AAC70919  70 YAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGL 149 human
AAB65515  70 YAGGPISSILVNKYGTRPVMIAGACLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGL 149 Trypanosoma cruzi
O15375    64 HMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANAL 143 human
AAB61338 154 AAAGSPVFLSSLSPLGQVLLEKFGWRGGFLIMGGLLLNCCTCGAVMRPLDAgmkrktekaQDKYEakEMLPMGGKseegi 233 chicken
AAC18120 149 AAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPG---------PQPRP--DPAPPGGR----- 212 Norway rat
P53988   151 AMAGSPVFLSSLAPFNQYLFNSYGWKGSFLILGGIFLHSCVAGCLMRPVQTsp------rKSKSKskVGSRQDGS----- 219 golden hamster
Q63344   156 AMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPVGPsp------rAAKSKskVGSRQDSS----- 224 Norway rat
AAC70919 150 AMAGNPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPnq------tTSKSKnkTGKTEDDSs---- 219 human
AAB65515 150 AMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPqq-----gkVEKLKskESLQEAGKsdant 224 Trypanosoma cruzi
O15375   144 ASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATs---------VAPEtkECPPPPPE----- 209 human
AAB61338 234 sttdgTKKtkkakkkpkkgKKLLDFSIFSN-RGFIIYTISKFILVLGLFVPPILLVNYAKDTGVPDTEAAFLLSIIGFID 312 chicken
AAC18120 213 -----ARH-----------RQLLDLAVCTD-RTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVD 275 Norway rat
P53988   220 -----MKKaskvs-taekiNRFLDFSLFKH-RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDKGVDEYNAALLLSVMAFVD 292 golden hamster
Q63344   225 -----TKRlskvs-taekiNRFLDFGLFTH-RGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAFLLSVMAFTD 297 Norway rat
AAC70919 220 ----pKKIktkks-twekvNKYLDFSLFKH-RGFLIYLSGNVIMFLGFFAPIIFPAPYAKDQGIDEYSAAFLLSVMAFVD 293 human
AAB65515 225 dliggSPKgekls-vfqtvNKFLDLSLFTH-RGFLVYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILGFVD 302 Trypanosoma cruzi
O15375   210 -----TPAlgclaacgrtiQRHLAFDILRHnTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSN 284 human
AAB61338 313 IFARPACGMVAGLKWVRPHVAYLFSFAMLFNGLTDICSARASNYTGLVIFCVFFGISYGMVGALQFEVLMAIVGSQKFSS 392 chicken
AAC18120 276 IVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPS 355 Norway rat
P53988   293 MFARPTGGLIANSKLIRPRIQYFFSFAIVFTGICHLLCPLADTYPALVVYSIFFGYGFGSVSSVLFETLMDLVGPARFSS 372 golden hamster
Q63344   298 MFARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLLFECLMDQVGASRFSS 377 Norway rat
AAC70919 294 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSS 373 human
AAB65515 303 MVARPSMGLAGNTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSS 382 Trypanosoma cruzi
O15375   285 IFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPR 364 human
AAB61338 393 AIGLVLLIEAFAVLIGPPSAGRLVDALKNYEVIFYLAGSEVVLSALFLAMATYCCLNRGKKTPPpeK-NPSAGGGSDTEE 471 chicken
AAC18120 356 ALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISS--G-RSAEGGASDPED 432 Norway rat
P53988   373 AVGLATIVECCPVLLGPPLAGKLVDKTKDYKYMYIASGTIVVISGIYLFIGNAINYRLLAKERK-------REKARKKKS 445 golden hamster
Q63344   378 AVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIVVLSSGIYLLICNAINYRLLEKERK-------REKARRKKS 450 Norway rat
AAC70919 374 AVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERK-------EENAR-QKt 445 human
AAB65515 383 AVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIGGLYLFIGMGINYRLVAKEQK-------AEEK-KRD- 453 Trypanosoma cruzi
O15375   365 ALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAvaAdALERDLFLEAKD 444 human
AAB61338 472 AESDvQEAE 480 chicken
AAC18120 433 VEAE-RDSE 440 Norway rat
P53988   446 ATHPsRESE 454 golden hamster
Q63344   451 ASQAsKEME 459 Norway rat
AAC70919 446 -----RESE 449 human
AAB65515 454 GKEDeTSTD 462 Trypanosoma cruzi
O15375   445 GPGKqRSPE 453 human
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