2LAH,3ESL


Conserved Protein Domain Family
Mad3_BUB1_I

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smart00777: Mad3_BUB1_I 
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Mad3/BUB1 hoMad3/BUB1 homology region 1
Proteins containing this domain are checkpoint proteins involved in cell division. This region has been shown to be essential for the binding of the binding of BUB1 and MAD3 to CDC20p.
Statistics
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PSSM-Id: 214817
Aligned: 36 rows
Threshold Bit Score: 120.792
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2LAH_A         15 ENVLQMLEAHMQ-SYKGNDPLGEWERYIQWVEENFPEN--KEYLITLLEHLMKEFLDKKKYHNDPRFISYCLKFAEYN-S 90   human
AAD27864       61 LAQRKQMEEEVr-TYKGADPLGAWYTFICWIEQSYPAGgsGSGLQTVLHQCLTKFEDDERYRQDKRLIKLFIKFMEKQ-K 138  fruit fly
XP_629565      41 EKEKQKFE-IIInEYQGEDPIDNWLKYIKWVQQSYPGGnmKEQLIVLLERCTRLFLSTEKYKNDPRYLRIWITYADMC-R 118  Dictyostelium...
NP_565767      63 IEKRRNLIEAId-EYEGDDPLSPWIECIKWVQEAFPPGgeCSGLLVIYEQCVRKFWHSERYKDDLRYLKVWLEYAEHC-A 140  thale cress
EAY84844       73 llaarrkmiEAIdEYSGEDPLQPWIDCIKWVQESFPTGgdCSGLVVIYEQCVRAFWHDDRYKNDLRYLKVWLEYAGNC-A 151  Indian rice
XP_309522      33 EEERKVHEKEId-GYEGNDPLLPWYEYFFWMEQTNVSNfkPAIQEQALRRCVQLYENDARYMQDHRFIKLCIKYIDAQ-P 110  Anopheles gam...
NP_608919      37 LNDKQAWEHAIs-LYQGPDPLDHWYNYICWYE-NHAQSdpELKYRETLERCLTVYEHNDYYRQDVRLVRLWLKYIAMQ-T 113  fruit fly
XP_001230995   19 EADKQAWEDAIr-GYNGTDPLDLWFNYITWYEQNR-SFdrLNNLRSIVEKCLLLYQDAEGYKQDTRMVKIWMKYIDMQ-Q 95   Anopheles gam...
NP_196170       9 ENLLASLIVDIk-SYSGKDHLLPWIRGVKKMKESLPSQilNEKLPRFLQKCAESFESDKRYKNDSRYIRVWLQLMDFV-D 86   thale cress
NP_588140      30 IQRLALFQEELDiIEELDDPVDVWYRCIEWLLETRFLG--METVNKMLDDAIQYLERCRFALNDVRHLLIQLAKIKQSyE 107  Schizosacchar...
2LAH_A         91 DLHQF------FEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASAVLQRG 135  human
AAD27864      139 DKIEF------YQQMYNNGIGTMLADFYIAWAYSYDLSGNMRKADEIFRLG 183  fruit fly
XP_629565     119 DPIEV------FSFLEVQRIGFYLSLLYEARAIVYENKGNYEQADKSFKQG 163  Dictyostelium discoideum AX4
NP_565767     141 DAEVI------YKFLEVNEIGKTHAVYYIAYALHIEFKNKVKTANEIFNLG 185  thale cress
EAY84844      152 DSEVI------FRFLEANQIGQSHTNYYLSYASVMESKNKLKKANEIFNLG 196  Indian rice
XP_309522     111 SPVEL------YNELYLRGVGTLCAELYIAWAYYYDAVDNFAKTEEVFQKG 155  Anopheles gambiae str. PEST
NP_608919     114 DPLHF------YQVLFQRGTGRQVAAFYIGWAAYYESREEYKDAEAVFNLA 158  fruit fly
XP_001230995   96 SPASY------YQMMYKKNIGTQCASFYIGWAE-----RDYKQAVSIFNLG 135  Anopheles gambiae str. PEST
NP_196170      87 DPRAL------LRTMEAKSIGTKRSLFYQAYALHYEKMKRFEDAEKMYRLG 131  thale cress
NP_588140     108 TPDELqqaakqFYQLASKGIGLELALFYEEYGSLLIRMQRWKEASEVFHAA 158  Schizosaccharomyces pombe 972h-
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