Conserved Protein Domain Family
COG5210

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COG5210: COG5210 
GTPase-activating protein [General function prediction only]
Statistics
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PSSM-Id: 227535
Aligned: 25 rows
Threshold Bit Score: 205.806
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1723580   233 DVNEIENEHQLSVADEDQTSRLVKGKMIFVGKEDFGEEADISNsvfieqngpnsdTVSGFKETSSIVNSSSTTEKPGVAL 312  fission yeast
19074232      --------------------------------------------------------------------------------      Encephalitozoon c...
19115731   19 PLNTSDDSKWKEYFDDNQILEQIDKDIRRTLPDLSFFQGKSEInk--------kpSVNNVSENISVNTEDDKVEEVGQKL 90   fission yeast
1351606     6 SVDASSGSVGSYMSKSVRKHWWSRKGYHPTGSSKNGSRLKISSde---------nFQDELVVLDDAFLCNVPLELPSTSN 76   fission yeast
19113812  154 PLFFHDDECISTIEYGKQITRDRFDPFDESGNMFWGGTHLLMQlkk-------yaSLEQSSHESQLYLVNPSPEDTVAFQ 226  fission yeast
19112106    1 ---------MESQSKKSSALKTLSSLWNGSSSATSDPVTVLDR------------SRTHHHRGRSTSSKAQPFRLDDSVY 59   fission yeast
19112293    1 --------------------------------------------------------------MKKKEIKQLKNEIKIALL 18   fission yeast
19075970    1 -------------------------MKEISLDYSSPSLQQTE----------------EQDRELNFIDSSMLRPTPPQES 39   fission yeast
1346228   134 PVLFFHDQLCPSTTDKLKRLRKSMNPFDDSDELYWGGVDLRNKine-------lmELKKSNLEPEFWLVNPSLNDLRNFV 206  baker's yeast
6324644    24 TSLMKSWRISSASSSKKPSLYKMNTTESTSLPSGYASSADRDRrt--------sdGNFEAMAKQQASTRRTSNSYSPLRY 95   baker's yeast
1723580   313 DSQNDTSIFNEEQtNSLTETFNDLTldhlPEnvesepvagkENETAKNESGASDndhkanvhvfvlkssedaitlneeki 392  fission yeast
19074232      --------------------------------------------------------------------------------      Encephalitozoon c...
19115731   91 NYTKITSIDQSQEtPVHLSTIDFSK----------------FQEECHLVLQGRIy------------------------- 129  fission yeast
1351606    77 AQKTAAESFSKLS-PQDQLLSLQLN----------------NVQESVFQQSTFN-------------------------- 113  fission yeast
19113812  227 SVELQKVISNNRLnSSSTPPTPRSSssifNPfrralhdlsfTVLERFSRVTNYGkse----------------------- 283  fission yeast
19112106   60 SDQPPKDHISLARsITRPESASESKiyapSAr---------SSLSLEAVVGKKVs------------------------- 105  fission yeast
19112293   19 NSDVETLSHIGKEgHGFLMKSLRKS----------------------VWVSLCG-------------------------- 50   fission yeast
19075970   40 DNRLAVEK-------PNIQPLQGHS-------------------PVPSFMSTAS-------------------------- 67   fission yeast
1346228   207 SKDLLESYNNSKKdTTELATAGVKLnekfQEwkwn---vmsKIADVTTKSTNFIdsw----------------------- 260  baker's yeast
6324644    96 VNPTLSTASNESPrPALLLRQHHQRhhhhQQprhsssgsvgNNCSNSTEPNKKGdry----------------------- 152  baker's yeast
1723580   393 atqddpLEAPTPIVASSSTIFLNSnqrndelsaSGSQEPHPKDGTNSTSslpldtnnlsnseppshvldassetieviqt 472  fission yeast
19074232      --------------------------------------------------------------------------------      Encephalitozoon c...
19115731  130 -----rLENESTSSSTTALSTPRQ---------SMDSKRTINAEAIAGEn------------------------------ 165  fission yeast
1351606   114 ------LPDALLDPGPASKEKQAv---------LSIGRPSWLPPKSKEE------------------------------- 147  fission yeast
19113812  284 ----vdRLMEHKVTKSILPHLPRElqvlleskrVQKLTEEYDPARMFLArwa---------------------------- 331  fission yeast
19112106  106 -----aKFAKYLSQTDDDWGVSNi--------kASKSLPRMARSTTPNSs------------------------------ 142  fission yeast
19112293   51 ------LSCRHRMECLSRSTSQSS---------YADQNQVHLDSERS--------------------------------- 82   fission yeast
19075970   68 ------TNISSSKINNNQTEFEQ----------LRDSYKSHGDLNSAIN------------------------------- 100  fission yeast
1346228   261 ----ltNNSPIQKSQIDNEYLQKLlnn----ekVKQIEQDYDSARVYLAnws---------------------------- 304  baker's yeast
6324644   153 ----fkDLDEDWSAVIDDYNMPIPiltnggfgtPVAPTRTLSRKSTSSSins---------------------------- 200  baker's yeast
1723580   473 ikklqnqvpetikdevgKKNTAFSPGTSLSTNHVKTKSRSAHNNSTSPFSTAVSswlnplrypsdksPRVISSYLESVFI 552  fission yeast
19074232    1 -------------------MVSSPGSKVFGENAIDEKLVRKLCFGGVGSKYRG----------------IAWKIIFQVVG 45   Encephalitozoon c...
19115731  166 ----------------kLGLHREAAERILFIYAKLNPGIGYVQGMNEILAPLYY-------------VLATDPTYENYYL 216  fission yeast
1351606   148 -----------------EKKHMREFEQIKKSAMRYDRQKQKEKIKMVEQKNKR--------------NLYLVNVWEREIL 196  fission yeast
19113812  332 --------------egiVEQSESNNSQPVNNAGVWTDAQREEDSSLGPFELVYIeerv------krdDPLSVEQWNSMFN 391  fission yeast
19112106  143 ----------------sRSLFPQNGVDTTTSRQKLHSSGRFPLPAKLAHRSVEVev----------aESNALVSRIKKFS 196  fission yeast
19112293   83 -------------------FFQYKLNPFLLRKHRSQLTKLLSVVFKHYPELCYY-------------QGLHDIAQILLLT 130  fission yeast
19075970  101 --------------------DSRIQSIIFELNQQCEKESIPVSNIDWLQWASV--------------PLFAYDLPPDPSN 146  fission yeast
1346228   305 --------------lgvKQEAERYQKQNKLFDSYRNNIFNDLNLTDELSDTEINnal-------qrqFPLTEAKWNSLWD 363  baker's yeast
6324644   201 --------------isnMGTSAVRNSSSSFTYPQLPQLQKEKTNDSKKTQLEIEner-------dvqELNSIIQRISKFD 259  baker's yeast
1723580   553 SKPRSIGDAQKLEILEYLQSQsstVSNQVFTLLSNFIQNPLFVLDE-CFDEFRNLILMHNSHTVHTVvwktisswtsydy 631  fission yeast
19074232   46 LRKQLHTGEVEVKYSKYVKMV---VKMGCSLTNGNGCGGEGFDVDG-SIPEGPDGMHYHKLALPEK-------------- 107  Encephalitozoon c...
19115731  217 CECDAFFLFTQMMVQVRDLYE---KTLDHDSDHGIHFLMSKFTERL-KKYDYELWENLEEKQIHPTy------------- 279  fission yeast
1351606   197 RNWP--DALKSSRYAGIWRQG---IPSRVRGRVWEKAIGNNLKLDY-QSFFNARANAQKREAAEKAEqmnna-------- 262  fission yeast
19113812  392 AHGK--LQVDVHRVLGIIFHGg--IQPSLRKEVWPFLLSVYPWDST-SEERRVIYLSLQEEYCTLKRkwyedihk----- 461  fission yeast
19112106  197 RILD-APIVDLNALRTLAWNG---IPSEHRPIVWKYLLGYLPCNASrREVTLKRKRDEYNAAKDSCFntntep------- 265  fission yeast
19112293  131 LPFSHALPLMEHLVFYRLRDF---MLPTLDGTVKQLQLILAVIKAR-DPTLYEYLIKADIQCYFALS------------- 193  fission yeast
19075970  147 PNATSSSPPPLTPILELIKQNnfcIPSPCRKLVWQSLVSAERNELL-TLYATLSTTNNSLDSSIRK-------------- 211  fission yeast
1346228   364 ENDG-RLRVTVNEVKDFIFHGg-lENDSLRGKVWGFLLEIYPWDSS-QDERVQIDQTLAAEYDQLKLtwskdflqfd--- 437  baker's yeast
6324644   260 NILKDKTIINQQDLRQISWNG---IPKIHRPVVWKLLIGYLPVNTKrQEGFLQRKRKEYRDSLKHTFsdqh--------- 327  baker's yeast
1723580   632 emqysslsikncDSDKAIRKDLDRTFAPEILSH----------------FFSNRQQleptdn---------iaestANLH 686  fission yeast
19074232  108 -------------IVHQIDLDIRRIDLRYRSYLg---------------TDISYMY-----------------------Y 136  Encephalitozoon c...
19115731  280 ------------YSFRWFTCLLSQEFPLPDVIR----------------LWDSIIA--------------------DQMK 311  fission yeast
1351606   263 --------nqfrEDVCALELDLQSTMPHYSLFH----------------TEGPLRR---------------------DLI 297  fission yeast
19113812  462 ----qfndrwfiEQRNRIEKDVHRTDRQHEYFQ----------------IEDLPHPdpqstft-------gtnmnmEMMK 514  fission yeast
19112106  266 -------ppldqTIWRQIVLDVPRTNPSILLYQ----------------NPLTQRM----------------------LE 300  fission yeast
19112293  194 ------------WLITWFAHDVSDISVVCRLFD----------------FFISSHP--------------------LTVV 225  fission yeast
19075970  212 ------------IIRMQSFRGPLEPFKYSSTTR----------------HKVSTES----------------------IF 241  fission yeast
1346228   438 ---dedeeeywnDQLFRISKDVRRCDRNLEIFQyntidglppppqqlpaNENNSTSpesandesddaddgvrnphlIHLQ 514  baker's yeast
6324644   328 --------srdiPTWHQIEIDIPRTNPHIPLYQ----------------FKSVQNS----------------------LQ 361  baker's yeast
1723580   687 RVLRSLAIVLPQVGY-TQGMSWIAGALLMHLP-----------------------------APQAFALLVFLFKNYH--- 733  fission yeast
19074232  137 RVLWLVAHKRPLLGY-IQGMADILIPFILVFLn----------------------------ENAERAESNAYFCYAR--- 184  Encephalitozoon c...
19115731  312 ARLFGKNDDGFNGAY-DFLMDFCCSILIELREs---------------------------iLERNFADSIKLLQAHFnvd 363  fission yeast
1351606   298 GLLRAYSYYRFDTSY-IPGTSFIGALLLLNMN-----------------------------LTSAFNCLANLLDKPF--- 344  fission yeast
19113812  515 DILLTYNEYDTELGY-VQGMSDLLAPIYVTFNd----------------------------NALTFWGMVGLMK--R--- 560  fission yeast
19112106  301 RILYVWASRHPASGY-VQGISDLVTPFIQVFLseyigdkdpmtyd----ialldetnrndiEADAYWCLSKLLD--G--- 370  fission yeast
19112293  226 YTCAQVVLDNRTSIIeLLWDNSGADLLHSYLC-----------------------------KLPASINVNQLIKNT---- 272  fission yeast
19075970  242 HVLHAFTLFDTTVEYnIEPLLWLTCAFLSYMA-----------------------------QGNAFRSLVCFIQRGG--- 289  fission yeast
1346228   515 NILITYNVYNTNLGY-VQGMTDLLSPIYVIMKe----------------------------EWKTFWCFTHFMD--I--- 560  baker's yeast
6324644   362 RILYLWAIRHPASGY-VQGINDLVTPFFETFLteylppsqiddveikdpstymvdeqitdlEADTFWCLTKLLE-Q---- 435  baker's yeast
1723580   734 LQNIFSSEMRGLSRVLHQFTR-LVEDYMPSLAIHFKRQDI-KTCSYASEWFLTLFAYKFPLEVVAHLYDILFLYGPGILF 811  fission yeast
19074232  185 LLDEIQYNMVELQSGMIEGLDfVLQTVDPDFHKFLQEIGL-EIHMFAFRWFNCLFVREFKVPILLKILDTIFASDSINES 263  Encephalitozoon c...
19115731  364 MPKLLNLTFELQHLRKTSKNDeDMSYVRKNSYNTNALANSlKNRVLSTYNTVKANVPQSSSSYTDNNKQKEPLEEKRSFF 443  fission yeast
1351606   345 LQAVYTQDTSSLKSFYQTFLD-TLKKNEPELATHLLIKLElVPDDFVYPLLRKLFIPMVSPEIASRILDCYVFEEDSFFI 423  fission yeast
19113812  561 LHFNFLRDQSGMHRQLDTLRL-LIEFMDPELFAHLEKTDS-SNLFCFFRMLLIYFKREFDWEVLLKLWDVLFTNYLSYDY 638  fission yeast
19112106  371 IQDNYIHAQPGIRRQVNNLRE-LTLRIDEPLVKHLQMEGV-DFLQFSFRWMNCLLMRELSISNIIRMWDTYMAEGVQGFS 448  fission yeast
19112293  273 CATISAVPFSSLPLDRYQISPySCLRNTGDPWEYMSRSNGlLLFRLQLAELQEEKHKPGTKVPAVFLQENIFN-GCNMLA 351  fission yeast
19075970  290 IREFFISQSSSLDESLFALVWgCLGDLAPSVAISLQRIKV-SSLCILYPSLACCFADSLQLPEALRLMDLIAIYGLEMFV 368  fission yeast
1346228   561 MERNFLRDQSGIHEQMLTLVE-LVQLMLPELSEHLNKCDS-GNLFFCFRMLLVWFKREFEMEDIMHIWENFWTFYYSSQF 638  baker's yeast
6324644   436 ITDNYIHGQPGILRQVKNLSQ-LVKRIDADLYNHFQNEHV-EFIQFAFRWMNCLLMREFQMGTVIRMWDTYLSETSQEVT 513  baker's yeast
1723580   812 NFGLALLSHSQESLLKLNMDRLISYLKEDIFLAFK--------------------ETQEGENYDTSLFVKTAF------- 864  fission yeast
19074232  264 LVYFGVALLMKFKSTLVENDFSHNILFLQSIYDReweeaei-------elilssaKFYRKVTSKQLLWSRLWH------- 329  Encephalitozoon c...
19115731  444 PSFRSSLDGVSPTQGRKSGEENIRTIFAKPTAHIGengwsnlk-----vkgssifQRFGNFVGDTMRYITEEEes----- 513  fission yeast
1351606   424 QLLMAVFKLLKPKLLVDDSRLVLSALLFEN--------------------------WDLGPEDEFMHFVYDISls----- 472  fission yeast
19113812  639 HIFVAYAIAERHREVLLNQTSAFDEVLKYFNELSGklaleptlicaeqcfyqfknKLALIDRKQMEETNSDEDg------ 712  fission yeast
19112106  449 EFHLYVCAAFLVKWSSELQKMEFQDILIFLQSIPTkdwstk---------dieilLSEAFLWKSLYSGAGAHLkr----- 514  fission yeast
19112293  352 AITVIGIGIVASQLIPKSTSNS---------------------------------------------------------- 373  fission yeast
19075970  369 RLLVAIFLKDRDKIVNMVSHEQWVKYLRSDVLASYrqpl------------vqkyTFYTRTPVDLNAWVEDSL------- 429  fission yeast
1346228   639 QLFFMLAILQKNSQAILQHLNQFDQILKFFNELNGkldwndlmvr-aellfkkfeKMMHVMERDLQNVSSSSSs------ 711  baker's yeast
6324644   514 SSYSMSSNDIKPPVTPTEPRVASFVTPTKDFQSPTtalsnmtp----nnavedsgKMRQSSLNEFHVFVCAAFlikwsdq 589  baker's yeast
1723580   865 -----------------SFEIQPDVldrYGNEYDILLKSEHEL 890  fission yeast
19074232      -------------------------------------------      Encephalitozoon cuniculi
19115731  514 ---------------seEEDLTTSRrkiGITSKRKVSVKRNVI 541  fission yeast
1351606       -------------------------------------------      fission yeast
19113812  713 ----------------sKETDLPTIapyLRNLLKTSQPQYTPS 739  fission yeast
19112106      -------------------------------------------      fission yeast
19112293      -------------------------------------------      fission yeast
19075970  430 -----------------ALNIDTTQfpsYLSYHETSVSHNTYR 455  fission yeast
1346228   712 ----------------sSTGVLPCQserLTLLLSKKPIIRHEG 738  baker's yeast
6324644   590 lmemdfqetitflqnppTKDWTETDiemLLSEAFIWQSLYKDA 632  baker's yeast
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