1ZTC


Conserved Protein Domain Family
MBLAC1-like_MBL-fold

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cd07711: MBLAC1-like_MBL-fold 
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uncharacterized human metallo-beta-lactamase domain-containing protein 1 and related proteins; MBL-fold metallo hydrolase domain
Includes the MBL-fold metallo hydrolase domain of uncharacterized human MBLAC1 and related proteins. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.
Statistics
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PSSM-Id: 293797
Aligned: 71 rows
Threshold Bit Score: 160.058
Created: 9-Jun-2009
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                        # # ##       
1ZTC_A     14 ELKILVTGGNVFVPgrLNAHFSTVVYLEHkdRRIIIDPGNlsSXDELEEKFSELGISPDDITDVLFTHVHLDHIFNSVLF 93  Thermotoga maritima
KKU56835    3 KVKVLVEGYAQVNPdsTWDATSTTTLIDTdkLKIIVDPGC--HRQLLLKSLSQISISTRDIDYVFLTHYHPDHCLLAGIF 80  Microgenomates (Am...
KKS45213    3 EVKVLIEGYAKEEEg-FELASSTTTLIREgdFKIIVDPGM--NRKLLLEALEKENLSKEDINYVVLTHNHLDHILLAGIF 79  Parcubacteria bact...
KKP38605    3 KVKVLVEGYAKVNAdgTWDASSSITLIDTgsKKIIVDPGC--NRKLLLNSLLNEKLTTGDIDVVFITHYHPDHCLLMGVF 80  Microgenomates (Wo...
AET65243    6 WISVLAEGYAVTLAggGFRASPSTVLLEEpgRRVLADPGA--DGKSLLSALRERGLSPSDIDLIFVTHGHLDHLLNLRLF 83  Methanosaeta harun...
KKR06488    3 KFKILIEGYARTGAngVYFASPTSSLIYDekVKVLVDPGT--NADALRSSFEREEMEFKDIDIVFLTHYHPDHFLNIRLF 80  candidate division...
KKQ92133    3 KAKVLVEGYAHPNEdgSYTASPTCTLVESngKKFLVDPGT--SREKLLEALKKENINESDLSFIYLSHYHPDHWLNTRLF 80  Microgenomates (Wo...
KKU29085    3 TVKVLIEGYAKINPdgTWDATSTTTLIDTgqHKIIMDPGC--HRQMLLAALAKENLKTGDIDIVFVSHYHPDHCTLMGIF 80  Microgenomates bac...
KKQ90520   20 QIKILIQGYAKKIAd-GWLASSTVTLIESdsKKIIVDPGC--NRTELLKALAGNKLTTTDIDYVLLTHNHTDHQLLTGIF 96  Berkelbacteria bac...
KKR30606    3 QVKILVKGYAKPRGe-GWIATSNTILVQTgkLNIVVDPGV--NKKLLLKNLKKVNLKTSDVDYVFMTHYHPDHVFLASLF 79  Microgenomates (Wo...
Feature 1                                                                 ##                  
1ZTC_A     94 ENATFYVHEvyktknylsfgtivgriyskvisSWKNVVLLKg--EESLFDEKVKVFHTPWHAREHLSFLLDtenagRVLI 171 Thermotoga maritima
KKU56835   81 EKATVYDSL-----------------------QWQKGPLGGdisGNILPETDIQIITTPGHTSDHASLLVPtp-kgKVLV 136 Microgenomates (Am...
KKS45213   80 ENAQILDEGa----------------------IYSFEGTIKn-hEGRIPGTNIEIISTPGHDQSHSTVLVDtkkfgKVAI 136 Parcubacteria bact...
KKP38605   81 ENAVVMDSI-----------------------QYQKGPIGGd-mGNEIPETDIKIIKTPGHSPDHSSLLVEtk-kgRVLV 135 Microgenomates (Wo...
AET65243   84 PDAEVCDGSf----------------------LYRGDEAIPy--GRFLPDTEIEVLPTPGHAPDHASLLVPsg-keTWLV 138 Methanosaeta harun...
KKR06488   81 PNVDLYDGTt----------------------RWHGDQEHFy--EGRLPGTDIELVPTPGHTMEQTSLVIEtveygIVFV 136 candidate division...
KKQ92133   81 PNLDIYDGEi----------------------CWSGDREIFh--QGKLPDVDVEILKTPGHATEDTSLLIEte-dgVVCI 135 Microgenomates (Wo...
KKU29085   81 ESATVYDSIq----------------------YQKGPIGGEv--KEFLPDTDVQIIKTPGHSPEHASLLVPta-kgKVLV 135 Microgenomates bac...
KKQ90520   97 ENAKVLNDTe---------------------iYENDKQIDH---KNIIPGTDLKIIQTPGHDQFHCALIVPtd-dgTYVV 151 Berkelbacteria bac...
KKR30606   80 EKAKVLDGDt---------------------iYEDDKETPF---ENFLPSTNIEVFPTPGHAHEHASLLVQtkdkgKIVV 135 Microgenomates (Wo...
Feature 1       #                                                #     
1ZTC_A    172 TGDItpnrlsyy------------diikgygsVQVKNFLDRVgriDLLVFPHDAPLK 216 Thermotoga maritima
KKU56835  137 AGDVfwwrvgekqaid----vnapdefasdlkQLSLSRSLALslaDFIIPGHGREFA 189 Microgenomates (Amesbacteria) bacterium G...
KKS45213  137 AADVfwwadneeqktdkesligredpyakdkkKLIESRKKILekaDYIIPGHGKMFK 193 Parcubacteria bacterium GW2011_GWA2_42_18
KKP38605  136 GADIfwwkeneeqeid----veknddfasdmkTLVETRKEVLkiaDFIIPGHGKMFR 188 Microgenomates (Woesebacteria) bacterium ...
AET65243  139 AGDLfwwrdgavprtdlpslldledelatdpeALRRSRIEALrraTVVIPGHGPPFR 195 Methanosaeta harundinacea 6Ac
KKR06488  137 CQDVfwwedgkqksdnvndllnnpdpfmaswkDLQNSRKIVLdraDWIVPGHGKMFR 193 candidate division WS6 bacterium GW2011_G...
KKQ92133  136 CPDVfwwedgkqksdnvedllnledpfandkeALLASRKLVLskaHIIIPGHGKMFK 192 Microgenomates (Woesebacteria) bacterium ...
KKU29085  136 AADVfwwgageeqkidid-khddfasdmatlkLSRSHALKIA---DYIIPGHGKMFK 188 Microgenomates bacterium GW2011_GWC1_46_20
KKQ90520  152 AGDVfwwmdndeqktdyeslikhkdpyvkdekVLGNSRKKILeigDFIIPGHGKVFK 208 Berkelbacteria bacterium GW2011_GWA1_39_10
KKR30606  136 AGDVfwwmdnekqrideksllakkdpftkdweALQESRKKILkiaDWIIPGHGKTFR 192 Microgenomates (Woesebacteria) bacterium ...

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