1WOZ,1NOG,1WVT,1RTY,2AH6


Conserved Protein Domain Family
Cob_adeno_trans
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pfam01923: Cob_adeno_trans 
Cobalamin adenosyltransferase
Cobalamin adenosyltransferase This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation.The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12.
Links
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Statistics
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PSSM-Id: 460384
Aligned: 506 rows
Threshold Bit Score: 39.7887
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1WOZ_A            2 FTKSGDDGNTNV-In---kRVGKDSPLVNFLGDLDELNSFIG-FAIskiPweDXKKDLERVQVE-LFEIGED--LSTqss 73  Sulfurisphae...
Q8ZVA6           12 gacPGDLGDTEVlWrgrhlCVSKASGIVKLFGALEAALGYIN-FAAmscKr--QKRCLFRAYWS-LFYLGLY--LSTgnd 85  Pyrobaculum ...
Q8ZWM6           15 FTCPGDSGDTVVyWkgsarPVRKDDPVVKLYGALDTAIAYSH-KAAnliPr-pQARIMRLVAFS-LMELGFY--LATgra 89  Pyrobaculum ...
WP_014552473     97 yfkekpeaMTQI-Fan--kLVYKDHPLIEYRGKLDSFQSQIL-EVM------------LVVETEeIPGLYQD--L----- 153 Halanaerobiu...
WP_011877657     79 fsekkpehMTQL-Kgk--nLVDKRHPVIRLRGKLDSFQALAI-DTI------------IDLQTFgYGQMAKE--L----- 135 Desulfotomac...
jgi:Clole_4086   80 klnekpehMTHL-Rdn--lLVFKDHPRIVFRGAIDSLEAEIV-MTQ------------IFAEKEhLPQIIAD--L----- 136
jcvi:TREAZ_1560   3 vlskkpehKTHL-Agn--rLVSKSHGRIAFRGMIDVLEAEVL-EAQ--------------VLASgLGEEWYCtcL----- 59 
jgi:Lebu_0074    90 iydkkpeyMTQL-Fgd--nLVVKNHKRIILRGKFDILQAEII-KYW------------KKYEKN--KKLESD--F----- 144
jgi:Xaut_5023     8 satAGDAGMTRL-Aig--tRVEKDSPTIELFGTLEELAAWIAvLADdplSp-eDRRILATVEND-LHELLQQ--VAApgt 80 
WP_011831866      9 dpRRGDDGTTSL-Agg--tRVEKNSPYMQAIGVVDELNSLIG-MAIaseCgsDLRVVLSETQDE-LVALSSE--LSSpgs 81  Burkholderia...

1WOZ_A           74 kkkIDeKYV---------KW-LEERTV-EYRk-ESG-----------P----VKLFVIPG-G--SEEASVLHVTRSVARR 123 Sulfurisphae...
Q8ZVA6           86 fyynkslyM------------LRKSLRcVLPmlPDS-----------P----LG-WVYCL----DRCCAAVNNARAWVRW 133 Pyrobaculum ...
Q8ZWM6           90 eyldtataL------------YRRALKlAYAaaPEG-----------R----LGSWLACA----SPECSAVDEARVWIRW 138 Pyrobaculum ...
WP_014552473    154 ------EESleimrnvlaAEvRDQELK-LDTiiGLTaaeirarshnpQkyfsVK-HILPS-TdlGKILIKLNSLRSSVRE 224 Halanaerobiu...
WP_011877657    136 ------EEVltlaravlrAEvTGEELP-EPGfaGLTsneireishhpDkhlgVK-HFLPS-PahGKIMARLNLLRTSIRE 206 Desulfotomac...
jgi:Clole_4086  137 ------EEIikfirrllrNEvCGEPIG-EFTlqGLDakelrehshhpSkyygIK-HFLPH-YkqGEMVAYLNKLRTLTRQ 207
jcvi:TREAZ_1560  60 ------GEVldylraimiAEvKSEPFP-SLKlfGLAldeihqqshdvKaafgLARHPLPD-QsmGPLVARINYLRARVRE 131
jgi:Lebu_0074   145 ------AQTyrfvrdlfiSEmTDMEFQ-ERNvlGYDidtlkdithntVkyfkT-GHLFEInIdyDESVIDLNYLRALSRE 216
jgi:Xaut_5023    81 -plLSpPYV---------QR-LDVLMD-GMEr-RLP-----------P----APSGAFPG-G--SPRAAFAAVARSVCRR 129
WP_011831866     82 -ivLTlAAL---------QR-VDKELT-RWLa-DLP-----------P----AAGIVLPR-G--TMAAALCFKARATCRT 130 Burkholderia...

1WOZ_A          124 VERNAVKYtkeLpei--nrxIIVYLNRLSSLLFAXALV 159 Sulfurisphaera tokodaii str. 7
Q8ZVA6          134 AERRLAAIeegRe------aIL-VLNHLSSLLFEIMRT 164 Pyrobaculum aerophilum
Q8ZWM6          139 AERRLVSLgeaPa------aKL--LNQLSNLAFEVMRT 168 Pyrobaculum aerophilum
WP_014552473    225 VEIAAVKAfrdEkgik-rpdIIKALNRMSSVFYVMMCK 261 Halanaerobium praevalens
WP_011877657    207 TELVAADGfvrEngeterkdIMETLNRMSSMIYIMMCK 244 Desulfotomaculum reducens
jgi:Clole_4086  208 TELIAYKAfkdEygqvsredIIKSLNRLSSLFWVMMFK 245
jcvi:TREAZ_1560 132 GELLAVRIfgrlt--grrqdLITAMNRLSSALWWLCCk 167
jgi:Lebu_0074   217 CELAAVEAfykEgkve-rldMLKALNRLSSILYLMMLK 253
jgi:Xaut_5023   130 AERRLVAQcdiDrglp-aasGIAYLNRLGDLLQQMARL 166
WP_011831866    131 LERELVGLeeaDrescadslRLPYVNRLSDLLHALART 168 Burkholderiales genera incertae sedis
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