Conserved Protein Domain Family
DUF4350

?
pfam14258: DUF4350 
Domain of unknown function (DUF4350)
This domain family is found in bacteria, archaea, and is approximately 170 to 200 amino acids in length. This domain is part of the glutaminase superfamily, suggesting it may have an enzymatic function. The domain is founded between two transmembrane helix domains giving it a membrane localization.
Statistics
?
PSSM-Id: 464118
Aligned: 83 rows
Threshold Bit Score: 45.1477
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q21NQ3            53 NKDVRREPVYAAREFLEKQGIETEYRRs--fALFDKLdgnSSRNTPgpndTIVL-FDSFgvISEARFEKLSPWLHSGGTL 129 Saccharopha...
jgi:CAP2UW1_3394  39 QSEARRNPWLALERFTARMGGQLTRASd--aRILDRL-----PAGS----LLLD-RQRAhlLTPERLHRLLAWVEAGGYL 106
Q9HW80            41 SPEARRNPYLAAELFLRKQGVTVSRADg--lEVLKEL---PPSGHT----LLLL-GSRSg-MTPGQARRLLQWSEQGGHL 109 Pseudomonas...
Q87X68            41 SPEARAKPWLAAEHFLRGRSVEVTTTDt--lAQLPDP---NQRTQT----LLLF-NDRAg-MTPAQTEQLLNWVISGGHL 109 Pseudomonas...
jgi:Pmen_3319     40 APEVASSPYLAAEHFLRKQGLKAQRAEg--lEVLDGL---PSQGQT----LMLL-ADRSk-MTPRQVERVLQWTANGGHL 108
WP_011912339      40 APEARSNPYLAAELFLRGLGLTVEHHEg--iGSVETL---PSEGRT----LLLL-GDRRn-LTPRQTERLLDWAAAGGHL 108 Pseudomonas...
Q0VPA0            42 DSSITRNPYSAAQQWLAQRGQPSKRILs--aAALFPL----PDTRT----TLVI-DKHRgmLTSNQVNALLEWVQDGGKL 110 Alcanivorax...
jgi:Plim_3741     75 SYSASADGFKALYEILEQDAFVYRND-----APLDRLmelVDPDGT----LLLIlNPPRi-PNEAEWNSLYSWVNMGGRL 144
WP_012259243      39 SFSSSDDGALALYRWLER--IVPGRVDrlayRPFALS----AAEGM----LFVL-GPTEr-YEPAQVAAVTEWVRDGGVL 106 Chloroflexu...
jgi:RoseRS_1833   38 TYSSAPTGALALYEWTRAMGYDARRLEy---RPFELT-----DDDA----VLVMlNPSAa-ISKDHARHIRTWVERGGTL 104
Q21NQ3           130 VTSTYNPrnkgvepdelfyylgvevhesispielrqgesqedaeqrvkqrrfpfegflkdiaeeakkteqknkQNiedge 209 Saccharopha...
jgi:CAP2UW1_3394 107 IAVAEHPgv--------------------------------------------------------------adPL----- 119
Q9HW80           110 VLIAERLwdede---------------------------------------------------------kksgDLl---- 128 Pseudomonas...
Q87X68           110 LFVAEQLwdeqk---------------------------------------------------------grsgDLl---- 128 Pseudomonas...
jgi:Pmen_3319    109 LFIAERLwdeee---------------------------------------------------------gksgDLl---- 127
WP_011912339     109 VVVAERLwdeka---------------------------------------------------------gksgDLl---- 127 Pseudomonas...
Q0VPA0           111 VVEGRPLpgildt------------------------------------------------------sdasasDWqdn-- 134 Alcanivorax...
jgi:Plim_3741    145 VYAPPPGe----------------------------------------------------------------vDS----- 155
WP_012259243     107 VMADNRPsprs-----------------------------------------------------------tlsPL----- 122 Chloroflexu...
jgi:RoseRS_1833  105 IFAEDTPhlfs-----------------------------------------------------------isdAL----- 120
Q21NQ3           210 flkkadksssrSETLEPE------QSAAKENEKAEGgedknsknktdssllQPEKLDKTDADKAEGSVEEKsdaksdekp 283 Saccharopha...
jgi:CAP2UW1_3394 120 -----------LDSLGVK------RVASPRKPARQAp--------------AVVDVLVPGAAQPLKLAAGGy-------- 160
Q9HW80           129 -----------LDSLDIR------QYLTEDFDDSQDraseet----adadaDEGSVDDHATEAPPEDTAGEeeepadsvp 187 Pseudomonas...
Q87X68           129 -----------LDRLQIRqylskdINAQDQQLSDAQpmlpip---lmtpvpKRKKTPWPELTRLYLENERApa------- 187 Pseudomonas...
jgi:Pmen_3319    128 -----------LDLLGIQ------QYMSDELDEEDGget---------eegHEEGEAYPQLTKLYLENEDApa------- 174
WP_011912339     128 -----------LDRLNLQ------QYATEELDEISQtp------------qSSTAEEHPQLTKLYLENERApa------- 171 Pseudomonas...
Q0VPA0           135 --------dplLFALGIT------VWDSPVPSDAGQedaird---llmalpTFVDSPLQYCLHSDNEALREdcarlacda 197 Alcanivorax...
jgi:Plim_3741    156 -----------LGPFDGE------ITPEQGPADDRI----------------PPQLNLPLGGRFLWWPEGEv-------- 194
WP_012259243     123 -----------LKAFDLE------LKIITQTSTATPvhp---------algSPPLTTLPVHTAVAIASTAP--------- 167 Chloroflexu...
jgi:RoseRS_1833  121 -----------FDELQMR------MTVITGTQEIERvp------------aLQPVFDQPPVRELNVRPRRA--------- 162
Q21NQ3           284 deqekk--ygsykhynpsecpklAAATLIPFSSEAEPLAVHFNRGrlfdymdesaepegwvgdengmlfaqylMNNG-QV 360 Saccharopha...
jgi:CAP2UW1_3394 161 ----------------------lLAAGERQPAWSAGQRGRGEQVLhf-------------------------hLGRGeVT 193
Q9HW80           188 dysal----trlylenerspayiGFDPDYHLYDPQNHAYAWANSGdathl-------------------lqmqHGKG-LV 243 Pseudomonas...
Q87X68           188 ---------------------ymSFDPAFHLEDPQDHAQSWANSAdathl-------------------lqisRGKG-LI 226 Pseudomonas...
jgi:Pmen_3319    175 ---------------------yiAFDTDFHLFDSQNRAHAWANSDaathl-------------------lqlyHGDG-LI 213
WP_011912339     172 ---------------------fiAFDTDFHLYDADNRAHAWANSAgathm-------------------lqlqHGDG-LI 210 Pseudomonas...
Q0VPA0           198 ppeptpltlhvsdnepdrrvqlfSDYVIWHDSWDEEEGNAPHLEWpveitgyadn--------dygsqlvqlsLGSG-QI 268 Alcanivorax...
jgi:Plim_3741    195 -----------------------TSTPGGKVLVSQDGSPQAVMVN----------------------------AGRG-SA 222
WP_012259243     168 ------------------------QPALAPLAVADTHPIVAGQR-----------------------------FGDG-YV 193 Chloroflexu...
jgi:RoseRS_1833  163 -------------------------LAPQRNDYAPLFGAADQILIag------------------------vrIGQG-YV 192
Q21NQ3           361 YITVNNHIWWNENIACLDNAYLLLKII 387 Saccharophagus degradans 2-40
jgi:CAP2UW1_3394 194 VAAAFDGQLSNRHIGEEDHADLYWSLL 220
Q9HW80           244 TVLTDAWIWQNRNIEQYDNAWLLWYLT 270 Pseudomonas aeruginosa
Q87X68           227 TVVTDADLWKTHSIGEHDNAWLLWYLT 253 Pseudomonas syringae pv. tomato
jgi:Pmen_3319    214 TVLSDPWIWQNRNINEYDHAWLLWYLG 240
WP_011912339     211 TALTDSWIWQNRKIDDYDHAWLLWYLT 237 Pseudomonas stutzeri
Q0VPA0           269 SVLTDLSLWSSERLLYFDHAWLLAWLT 295 Alcanivorax borkumensis SK2
jgi:Plim_3741    223 LFVASPWIFSNQLLTYGDNSALAFELI 249
WP_012259243     194 IVVSSLYPFTNDGLRQPESAAFMLNLL 220 Chloroflexus aurantiacus
jgi:RoseRS_1833  193 YISATTHPFTNRGLRDRQHAALVLNML 219
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap