2LEM


Conserved Protein Domain Family
Apolipoprotein

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pfam01442: Apolipoprotein 
Apolipoprotein A1/A4/E domain
These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.
Statistics
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PSSM-Id: 460211
Aligned: 92 rows
Threshold Bit Score: 54.9624
Created: 21-Mar-2022
Updated: 13-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2LEM_A              44 NLLENWDTLGSTVSQLQERLGPL--TR--D-FWDNLEKETDWVRQEM------NKDLEEVKQKVQPYLDEFQKKWKEDVE 112  house mouse
CAL78778          1282 AMTGKTDEIVTYVQQQSERLSQMldGKrgT-LVETLNSKTNQLTIEI------DRVTTDALKQIEMRGQAFAQTVNGNGS 1354
Q89HV2            1274 AMTGKTDEIVTYVQQQADRLSNMidAKrgA-LVDAIGSKTSQLTLDI------DRVTSDALKSIETRGHAFSQTMMGNGS 1346 Bradyrhi...
jgi:Mrad2831_1948 1401 VLEEAPAAVSALVETRERQLAATldARtqR-LQTLFEEAQAGLRDLV------DGRGQEVADAIAARTEGLRTTLDAAPA 1473
jgi:Msil_3548      771 SAQESAGALAAQTQTLQERLAA---------AVDTASERSDEIARRI------ADSTRDQTETLASRTDELHAQLGATID 835 
vbi:Avi_2239       941 TLDSKIEQISDAASDADMRIELAlgNRmdT-IRAVYEESETRLSGTI------DAKLGALTETLGTADSRIEQAFGSKAD 1013
Q92K98            1500 RLEATAAKVSETARQASDMLSTS--TRliEgKVDKLSDISSSTLSQIggivgrFEDHSKVLGQASDLLAAAQSNLVSTLE 1577 Sinorhiz...
WP_012592506       306 aaaevgaSLNAKGEEITNALSRG--RD--D-LIESLSNHGNDLVGRL------TQRGEAATADLAQASASVAQTLDQRLA 374  Methyloc...
KTS47252          1042 RLQAIAETLDQRARLVDESFG----VQafE-AIRLIEARTRAVDEEL------AGRTRDLVAMIADRTGGLDGAMAERVR 1110 Methylob...
WP_089231416       684 RTEEAAAALRAAADQASQAAETQ--TR--D-AAARLAEALDTLRTAS----------GEVTGAVEAETAILTARFRDAAD 748  Methylob...
2LEM_A             113 LYRQKASPQGAELQE------SARQ-KLQELQGRLSPVAEEFRDRMRTH----VDSLRTQLAPHSEQMREsLAQRLAELK 181  house mouse
CAL78778          1355 EVARTITSAGELATT------AITK-SLKDLEQASRAAIEQSRQVSVAA----VTEMQETSKILRTDTVA-LFERLREGN 1422
Q89HV2            1347 EVARTINAASEMATG------AVGK-SLKDLEQASRAAIDQSRQVSIAA----VTEMQETSKILRTDTVA-LFERLREGN 1414 Bradyrhi...
jgi:Mrad2831_1948 1474 QMADLLDTRLSDLQG------LFER-AQGEIDRLVDSRGRQIAGTIEHR----TQALQATIEGVNPAIAGlLEERETRLA 1542
jgi:Msil_3548      836 AVDAHLEEISRRLAVvsessvGALAeQTAALQDRLSAVARTVNEHAGEIsrrlASSARDSVGTLAERTQA-LEQRIEAAL 914 
vbi:Avi_2239      1014 QLRAVYEEGQARLTQ------TLDS-KVDQLSDVAAEADMRIEFALGSK----VDSIRSVYEDSEARLAGtIDAKLGQLI 1082
Q92K98            1578 ERQDALRTLSVGLVQ------R-SE-EIERTMRALEGFVDGAFQRAEER----SGQVAGNLRSGIQSSFSdVGRLLSNTE 1645 Sinorhiz...
WP_012592506       375 EINARLRDAQEALAA------DLGA-RGDSLSQRLAVVGAGIADTVSSR----GDSLAARLEETSGRLHEvVAVQGGALG 443  Methyloc...
KTS47252          1111 ALTGTIEEATRGLEA------ALAN-RADSMIRLVDERTESADAALAAR----TEAVHAAFAERADLLGRlIDERIAAMS 1179 Methylob...
WP_089231416       749 RAGTELGARGTEAVA------AVRA-ALDDLNRELAARTGDATGSLAEA----ARAISADLAARIGEMEAaFGEHGRGVA 817  Methylob...
2LEM_A             182 SNPTLN--EYHSSAKSHLKSLGEKARPALEDLRHSLM 216  house mouse
CAL78778          1423 ILLQEVltGAHDNLNSLERALVARVADFVTAMNDVTS 1459
Q89HV2            1415 ILLQEVltGAHDNLNSLERALVTRVADFVSAMNDVTS 1451 Bradyrhizobium japonicum
jgi:Mrad2831_1948 1543 ETLKERtgELQTLFDRVQNRLGALVEGTGRDVSERVD 1579
jgi:Msil_3548      915 SLLNEKsdAIGERLASTAEQSADAVAGQSEALRERLG 951 
vbi:Avi_2239      1083 ETVGFAdsRVQQALGSKADQIREAYEANHGRLAEMLD 1119
Q92K98            1646 QRATEAaeALRDTLVKASDEAAASVEGVFSQAEERSR 1682 Sinorhizobium meliloti
WP_012592506       444 DHLAEAgeRFSRMIAERVSSARETLDQSGQSLVALFE 480  Methylocella silvestris
KTS47252          1180 GELDEKgrAVFGAIGGRITELARLLDRGGSSLAELID 1216 Methylobacterium radiotolerans
WP_089231416       818 ELLASHadETQARISGTGRDIVLAVASQGARIADTLS 854  Methylobacterium radiotolerans
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