Conserved Protein Domain Family
TMEM52

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pfam14979: TMEM52 
Transmembrane 52
This family of transmembrane proteins is found in eukaryotes. Proteins in this family are typically between 160 and 236 amino acids in length. There is a conserved LLCG sequence motif. The function of this family is unknown.
Statistics
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PSSM-Id: 464418
Aligned: 10 rows
Threshold Bit Score: 148.079
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9D702        30 RNCDPSDQCpPQARWSSLWHVGLILLAILLMLLCGVTASCVRfCCLRKQTHTQSHTPAawqPCDGTVIPVDSD-SPAHST 108 house mouse
XP_006237164  36 ENCVNTDHC-LTADWVHLWYIWLLVVVGALLLLCGLTSVCFR-CCLNRPENGEDGAPP---PYEVTVIAFDHD-STLQNT 109
XP_007503800  26 ENCVAPEHC-LTTDWVHLWYIWLLVVIGALFLLCGLTSICLR-CCLRRQQTGEEVGPP---PYEVTVIAFDHD-STLQST 99 
XP_002938900  86 DDCHKPG-CsQGTSWVNLWYVWLILVTIFLLLLCGTTASCIKfCCRKKKPPVQT---FqnhPCEVTVIAIDND-STIHST 160
XP_002724499  30 RRCDPSDQCpAQARWSSLWHVGLTLLAVFLLLLCGLTASCVRfCCLRKQARVQSHSPSawqRCHLTVIRVDSD-SPVHST 108
Q8NDY8        36 GSCDPSDQCpPQARWSSLWHVGLILLAVLLLLLCGVTAGCVRfCCLRKQAQAQPHLPParqPCDVAVIPMDSD-SPVHST 114 human
XP_003216844  26 KSCTNADNC-ADTEWVQLWYIWLVIAICGLFLFCGIVCLCVRcCCLKCYHAREETSHP---PYEVTVIAFDRDsSTLQST 101
XP_005040266  24 EGCLNTELC-SGTEWDRLWYIWLVLVVGGLLLLCGLISVCVR-CCFQCHQTGDESGPQ---PYEVTVIAFDHD-STLQST 97 
XP_010848289  30 GSCDPSDQ--------------LILLTALLLLLCGVSASCVRfCHLRKRAHSQPHLPPapePCDLTAIPVDSD-SPAHST 94  Bison bison bison
XP_012669212  55 ENCGSHEq--------------LLVAIGALVLLCGLTSLCFRcCCLSRQQNGEEGGPP---PYEVTVISFDHD-STLQST 116 small-eared galago
Q9D702       109 VT-----------------------------------SYSSVQYPLGMRLPLYFGEPDPDSMVPptYSLYASelpPSYDE 153 house mouse
XP_006237164 110 IT-----------------------------------SLQSVFGPAARRILAVAQAHSSLGQLP--SSVDTL---PGYEE 149
XP_007503800 100 IT-----------------------------------SLQSVFGPAARRILAVAHSHNPM-QIP--SLSSTLempPGYEE 141
XP_002938900 161 VT-----------------------------------SYSSVQYPH----MFPFADPDRSAMSPpaYSLYAMelpPAYEE 201
XP_002724499 109 VT-----------------------------------SYSSVQCPLGMRPPLPFGELDLDPLAPpaYSLHAPelpPSYDE 153
Q8NDY8       115 VT-----------------------------------SYSSVQYPLGMRLPLPFGELDLDSMAPpaYSLYTPeppPSYDE 159 human
XP_003216844 102 IT-----------------------------------SLHSVLSPAALRILAVAHAQSAGQARSqpAGTETP---PVYEE 143
XP_005040266  98 IT-----------------------------------SLHSVFGPAARRILAVAHSHNAAQGTPplSASDTP---PVYEE 139
XP_010848289  95 VTcecwhtspggppacrggrgpvrarptptnpswipaAYSSVQCWLGMQLPLPFGELDLDSTTLpaYSLYAPeppPSYEE 174 Bison bison bison
XP_012669212 117 IT-----------------------------------SLQSVFGPAARRILAVAHSHSSLGHLP--SSLDTL---PGYEE 156 small-eared galago
Q9D702       154 VVKMIKarEEVAAPSEKTNSLPEAL 178 house mouse
XP_006237164 150 ALGMSR--FTVARCGQKAPDLPSVP 172
XP_007503800 142 ALHMSR--FTVSRCGQKAPDLAPVP 164
XP_002938900 202 AIKMAKtnSE-AGPSASAPKLEGIS 225
XP_002724499 154 AVKMARpgEEDLAPSQKPSALPGVS 178
Q8NDY8       160 AVKMAKprEEGPALSQKPSPLLGAS 184 human
XP_003216844 144 AIHMNR--FTVSRSRERPPELQPVP 166
XP_005040266 140 ALHMSR--FTVAKAGQKVPDLDPVP 162
XP_010848289 175 AIKMTKtrQE------------EPP 187 Bison bison bison
XP_012669212 157 ALHMNR--FTVARSGQKAPDLPPVP 179 small-eared galago
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