Conserved Protein Domain Family
LNP1

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pfam15419: LNP1 
Leukemia NUP98 fusion partner 1
This family of proteins includes leukemia NUP98 fusion partner 1, the gene encoding this protein is involved in a chromosomal translocation with the NUP98 locus in a form of T-cell acute lymphoblastic leukemia.
Statistics
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PSSM-Id: 464709
Aligned: 14 rows
Threshold Bit Score: 176.953
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001503553  84 DDEDVSFAKWMSSFWGHSWIEEDERGLRDR--HRSQHASYRKTSLPCP-------------------FPVL-------PR 135
XP_007493635   5 DDDDVSFAKWMSSFWGHSWIDENERDLRNNreRRSQDIRARRTSLPCPt-----------------qFAALpmtsthgSS 67 
XP_003428989   5 DDDDVCFAKWMSSFWGHSWMD--EREGRAQrrRRSQSLSDRRASLPSPa-----------------qLSVLhtprlpgSS 65 
XP_429574      5 EDDDISFARWMSSFWGHSLIDENEKEGRGHkkRQTRSLSERRASLPAR-------------------LSSLhttrlhaSA 65 
XP_003219229   5 EDDDISFARWMSSFWGHNVSDEKEQESRAHrkQQ-----ERRASLPAK-------------------LSAIhmtkfhgST 60 
XP_005654127   7 DDDDVCFAKWMSSFWGHSWIEEDERGLRDR--HGSQDAISRKTSLPCPeksptnqgdkisvqhqicmFPVL-------PR 77 
XP_006098432   9 DDDDVSFAKWMSSFWGHSWIEEDERGLRAR--RGSQDTGYRKASLPCP-------------------FPVL-------PR 60 
XP_004771995   7 DDDDVSFAKWMSSFWGHSWIEENERGLRDH--HGPQNATHRKTSLPCP-------------------FPVL-------PR 58 
XP_013965606   9 DDDDVSFAKWMSSFWGHSWMEENERGLRGR--RGSQDASYRKTSLPCP-------------------FPVF-------PR 60 
XP_006248279   9 DNDDVSFAKWMSSFWGHSWRDKDERGLRDH--HRLQEASYRKASLPCP-------------------FPAF-------PS 60  Norway rat
XP_001503553 136 -ITSSDSHPR--RRSHEDQGFQCRTHMQDYRKCSGDGSFKEPLESTGRSHSkMQAFSESSEQQLCFRTKRSVSLGPESRQ 212
XP_007493635  68 rVVPVSGHPR--RHSQEDYGFQGHHHMKA-KICSQSGSLQGQMEPKGRSHS-IQEFSEHFEQQLCFRTKRSVSLEPEAKK 143
XP_003428989  66 -RAPSSGQLR--RHSQEDQEFRSYHPGKTCKT-------REPQGYDGRSHS-IQEFSESFEQQLCVRAKRSVSLEPEGGK 134
XP_429574     66 -KGSSSGHLKgsKEFQEDQDVKYRHHKKASRTPSADSS-----GPETRSNS-MQEFAESFEKQLHFKSKRSVSLQPEGMK 138
XP_003219229  61 -KIPSSGHLKcgKELRKDQDTNCHCHTKACRKSSSGSSPQVASGPNSRSNS-IQEFSESFERQLHFKNKRSVSLEPEGMK 138
XP_005654127  78 -LMSSDSHPR--RHSYEDQGFRSCTHMRDYRKRSGDGSFKEPLESKERSHSkIQAFSESFEQQLCFRTKRSVSLGPESRK 154
XP_006098432  61 -VTSYDSHPR--RHSHEDQGFRCHNHMREYRKRSEDGPFKDPLESNRRSHSkTRAFSESFEQQLCFRTKRSLSLGHESRK 137
XP_004771995  59 -ITSSDSHPR--RHSHEDQGFQCHTHMLDYRKCSADESFKEALESKGRSHSkIQAFSESFEQKLCFRTKRSVSLGPESRK 135
XP_013965606  61 -IPSSNSHPR--RHSHEAQGFQCHSHIPDYRKFSADESRNEPLESKRRSHSkIQAFPESFEQQLCFRTKRSASLGPESRR 137
XP_006248279  61 -IAPSDCYPR--RHSHEDQASR---RMRYHRKCSVDGSFREPIEPPRRAHSkMQEFSESFAQHLCLQTKCSPA-GPKGRK 133 Norway rat
XP_001503553 213 ERNERECLRM-ETGSCKKAEERRSCKKTEHR 242
XP_007493635 144 ERKERESLRI-STEAHQETEERRKLKEKKQG 173
XP_003428989 135 ARKEREGLRT-KTRSHKRVGERKGSKKEE-G 163
XP_429574    139 ERRER--LHLrKNRSHKRMGEKSEPGGAQKD 167
XP_003219229 139 ERREREKLRIpKSRSHKKTSEKKEPKMEQea 169
XP_005654127 155 ERNEKECWRL-EMRSHKKVEERRSSRKEELG 184
XP_006098432 138 ERNERESLRM-ETRSREKAEERRSSGKEEHG 167
XP_004771995 136 ERRERECLRM-EIKSRKKVEERRNPRKEEHG 165
XP_013965606 138 ERNERECLRM-EIRSQKKVEEKSSSRKDEHG 167
XP_006248279 134 ERNERHCLET-NMRSYKKVEDRRTSMKETPG 163 Norway rat
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