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PKc_like: Protein Kinases, catalytic domain
The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-speci...
View in Cn3D
SH2: Src homology 2 (SH2) domain
In general, SH2 domains are involved in signal transduction; they bind pTyr-containing polypeptide l...
FERM_F1: FERM F1 ubiquitin-like domain
This is an F1 lobe domain consisting of a ubiquitin like fold found in FERM region of Jak-family tyr...
FERM_F2: FERM F2 acyl-CoA binding protein-like domain
This is an F2 lobe domain consisting of an acyl-CoA binding protein fold found in FERM region of Jak...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
PTKc_Jak2_rpt2: Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 2
PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in prot...
PTK_Jak2_rpt1: Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 2
Jak2 is widely expressed in many tissues. It is essential for the signaling of hormone-like cytokine...
FERM_C_JAK2: FERM domain C-lobe of Janus kinase (JAK) 2
JAK2 has been implicated in signaling by members of the type II cytokine receptor family, the GM-CSF...
SH2_Jak2: Src homology 2 (SH2) domain in the Janus kinase 2 (Jak2) proteins
Jak2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathw...
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