Conserved Protein Domain Family
Iwr1

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pfam08574: Iwr1 
Transcription factor Iwr1
Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.
Statistics
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PSSM-Id: 430085
Aligned: 93 rows
Threshold Bit Score: 28.7727
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EED21949       400 GDYVYDTYVRvpihtvtssvsgaapqsditgyedplaeantpggitidptrTDVGVVVITSDDEELWdqyleddQDSEvd 479
ybcl:Ecym_3362 137 LEYVYDVYIRevlpedd----------------------------efvldeGTVGYIRIVEEQGELL-------PDEDel 181
CCH59770       169 LDYVYDIYKLepvnett----------------------------disslkGSVGSVRIVKVDTDLI-------HDEIdn 213
XP_001645386    40 LDYVYDIYRLenmkde-----------------------------deqlnrLKIGRVKIVNIDTELV-------HDEEsd 83 
CCF56120       139 LDYVYDIYHLekisdn-----------------------------epfnntANVGFVKILNKDIDLL-------PDESde 182
CCC68688       156 LDYVYDIYHLesvpede---------------------------mtryeqqN-VGFVKIVNKDMDLL-------PDEEed 200
CCK68216       155 LDYVYDVYKLeeipede---------------------------issypidN-IGFVKIVNKNMDLI-------PDAEsd 199
XP_002497545   156 NDYIYDIYHLeslkddd---------------------------lnsykyeD-LGFVKIVNKFIDLV-------PDEDtd 200
CCD23369       159 LDYVYDIYHLenlpdeee--------------------------iskykrdNKIGFVKIINTDMDLV-------PDEDed 205
XP_003682830   137 LDYVYDIYHLekvpeke---------------------------fdsykdaNDVGFVKIIDSNIDLI-------PDEEsd 182
EED21949       480 ----wdGDDVDSNAEDNPANDYPDDE 501
ybcl:Ecym_3362 182 sdsqllSDDEDSNEEHYYRNDYPDDE 207
CCH59770       214 seaelrSDDEDSNEENYYRNDYPEDE 239
XP_001645386    84 dnglnvLEDDDSNDENYYRNDYPEDE 109
CCF56120       183 enddflSDEEDSNDENYYQNDYPEDE 208
CCC68688       201 snneirSDDEDSNEENYYQNDYPEDE 226
CCK68216       200 ge-llrSDDEDSNDENYYRNDYPEDE 224
XP_002497545   201 p--eqcSDDEDSNEENYYQNDYPDDE 224
CCD23369       206 edvlarSDDEDSNEENYYQNDYPEDE 231
XP_003682830   183 sidkvrSDDEDSNEESYYQNDYPEDE 208
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