Conserved Protein Domain Family
FAM198

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pfam15051: FAM198 
FAM198 protein
This family of proteins is found in eukaryotes. The function of this family is unknown. Murine FAM198B is downregulated by FGFR signalling.
Statistics
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PSSM-Id: 373510
Aligned: 6 rows
Threshold Bit Score: 507.023
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003200182 246 ESWNQTKAESLPWFSADDIKKMALLSRGTVVSKAR---------LPGHGQVLQVGLSdkn--dtFASAGHLKRcqKESCA 314
XP_694732    167 SSIRIYSTRAPPWFSNEDITAMRFLADSKITQIDE---------VAHRDFSSLILFK-------SATNRSDNA--TKCCG 228
CAG04640     165 SSIRIYSPKAPSWFSPEDVKAMRFLADAKVVRMKK---------MPQEDFSSLLIFEsee-ggnHKTLEEGTLcgGR-CG 233
XP_009238681 203 SNIRIYSESAPSWLSKDDIRRMRLLADGAVAGLRP---------VSSKSGARLLVLE-------GGAPGAVLRcgPSPCG 266
XP_002602943 176 ENIRVYA--LPPWFSETDLLDMHRLADENMTFAGRdtrgldwwtLGTTGKTSETLLT-------EEGEVSAMEckSH-CI 245
Q3UY90       236 AGTAAW-GQVPPWFMEHDAQTLRLLVHGKVVGKAR---------VPAHGQVLQVGLSagdalqdISPLRLSQFcsQGLCG 305 house mouse
XP_003200182 315 LIKRPNDWSEVFAFHLDRVLGLNRSLPAVLRAFHSeil-pykYTSGSPRPVVWWDPSIQhlsdAENDQNSFSLTWPEYQA 393
XP_694732    229 VVKRPVDMSEVFAFHLDRILGLNRTLPAVSRRFHS-------LGEGQPCPVVLWDPSLG----PVADQPSEKLNWGSYQT 297
CAG04640     234 VIGSPVDNTEVFAFHLDRVLGLNRTLPAVSRKFSY-------LHDGHLCPVVLWDATVH-----LEENSVLKLTWGEYQN 301
XP_009238681 267 LLKQPLDMSEVFAFHLDRILGLNRTLPSVSRKAEF-------IQDGRPCPVILWDASLSp--aSNDTHSSVKLTWGTYQQ 337
XP_002602943 246 IVDDEKRLHQVFAFHLDRVLGINRTLPMVARSFTTdndvrrrVT---IRPVSLWDPSILi---TGSGHSTMYIHWNTYQH 319
Q3UY90       306 LIKRSKDLHEVLSFHLDRVLGLQRSLPAVARSFHSpll-pyrYTDGSVRPIIWWAPDVQhlrdPDEDQNSLALGWLQYQA 384 house mouse
XP_003200182 394 LLKSRCGIQ--V-----PLNFTTCVGVHHSEWGRLALFDFLLQVNDRLDRSCCGFRADPSDLCIENLLHVKCGNPKDLNL 466
XP_694732    298 SLKHKCWHRgvT-----PKPEWGCSSIHHHEWSKLVVFDFLLQIYERLDKNCCGFKPRPEDTCVELGYHEECRDKDSIEL 372
CAG04640     302 TLKQRCLVPksAi----PKPDSICSTVHHYEWSKLALFDFLLQIHNRLDPSCCGFKPRHADVCVQLGPHAECRNQAHIQL 377
XP_009238681 338 LLKQKCWQNgrV-----PKPESGCTEIHHHEWSKMALFDFLLQIYNRLDSNCCGFRPRKEDACVQNGLRPKCDDQGSAAL 412
XP_002602943 320 MLKSHCWGKgsVskikrPTSSYHCTDVLHSEWCRMAMLDFLLQIYDRLDRSCCGFHPSSSEQCVLEATHSDCDNDHRVML 399
Q3UY90       385 LLARGCKWPgqI----------PCLGIHHAEWARLALFDFLLQVHDRLDRYCCGFEPEPSDPCVEEGLREKCRNPEELRL 454 house mouse
XP_003200182 467 VHILVRKTEPSKLVFIDNAGRPHQPHDNLNFRLVEGIDEFPEKAVSVLQS-GCLEKMLLHSLSVDQEFWLSREEASGLKS 545
XP_694732    373 THIIHRRHDPHHLVFFNNKGYFDRDEDNLDFRLLEGIKELPDQCVSVLMS-QRLREKLLQSLFLDQEYWDSQGGRQGIEK 451
CAG04640     378 RGI-RRGHDPKHLIFTNNRGFFDRNEDNLDFRLLEGIKELPEQAVSVLQS-SKLRVRLLQSLFLDQRYWESQGGRQGIDT 455
XP_009238681 413 AHIIQRKHDPRHLVFIDNKGFFDRSEDNLNFKLLEGIKEFPASAVSVLKS-QHLRQKLLQSLFLDKVYWESQGGRQGIEK 491
XP_002602943 400 DHILQRRGDTKHLVLVENNARFNVSEKRLNYRLLEGIDVFPKSAVALLKTpGRLRQNLVQSLFTDRLYWEASGGRHGVER 479
Q3UY90       455 VHILVRSSDPSRLVYIDNAGNLQHPEDKLNFRLLEGIDGFPESAVKVLAS-GCLQNLLFKSLQMDQVFWESQGGAAGLKH 533 house mouse
XP_003200182 546 LIQHTEQRAKALLRHIQEKNLRLNRDL 572
XP_694732    452 LIDVIERRAKVLLTYINAHGIKVVPMN 478
CAG04640     456 LIDVIERRAKVLLTYINAHGIRTVTMN 482
XP_009238681 492 LIDVIEHRAKILITYINAHGVKVLPMN 518
XP_002602943 480 LIDVIETRAKALLRHMKEKKIRVAQMN 506
Q3UY90       534 VLETLESRGQILLRHIKKHNLTLFRDK 560 house mouse
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