6O7W


Conserved Protein Domain Family
V-ATPase_C

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pfam03223: V-ATPase_C 
V-ATPase subunit C
Statistics
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PSSM-Id: 460851
Aligned: 113 rows
Threshold Bit Score: 242.044
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6O7W_O        11 FILISLPQnaqpvTAPGSKTDSWFNETLIg--GR-----AFVSDFKIP-EFKIGSLDTLIVESEELSKVDNQIGASIGKI 82  Saccharomyces c...
A0E3Z9         3 YYLIGAPH-----KSNEQTAWLETEKHVLtsgISrq-akGRILQTEIG-KFKLGNLDHLMFINDSLLKQESVVESLLKKI 75  Paramecium tetr...
EGR27357       4 FLIGSTLI-----QGNQAQTWENIRKEVSslsQN-----LKQIDVESS-KFKLGNLDSLMHANETMLKLEQQIEGLLKKI 72 
Q7RCK7         9 FIACSTGD-----NTSREYIYTILKNRLLgshVC-----IDTNILDVPtNLKFCTFDDLLKCADDLQKYDSYAYGCLKKI 78  Plasmodium yoel...
EEA06592      14 YWIVACALa----EEGLDAIYHEMNVNLKkvgQN-----IEVMQFDIPfSLKFGAFDDLVRLADELIKHDTGIEVVLRRV 84 
XP_004356034   7 FWLISAP------NRPGADIFDIVNTKTAk--ENs---lSENVKFNIP-ALRVGTLNSLIALNDDLAKVDNFVELTSKKI 74 
XP_001708227  86 PTLLTVYG-----FATNDRKFNYLLKLRQasnGGvvepvLVSERLSLP-------VDQCLTVHDQVKKLKVSVLGLLERY 153
Q388J5         5 FLLLGLPF-----LPTGADSFAFQYKNLVsllGAa---gKDVCSFAVP-NFKVGTLDSLIEASDELAKLDLQVENSLEKQ 75  Trypanosoma brucei
Q4QDY6        37 FIILALPYl----QQSQDSLQSAQYEALVrqmGPl---gQTFRHFFIP-NLKIGTLDSLMEASDELAKLDPTMESTLQKL 108 Leishmania major
XP_001012282   3 YFLVGAENl----FGDSDKTFSRITTELGnlaTI-----KNRIDVQIR-DFKLSNVDQLISSNEAMLKMETHIESILKKI 72  Tetrahymena the...
6O7W_O        83 IEILQGLnet-stNAYRTLPINNMP----VPEYLENFQWQTRKFKLDK-SIKDLITLI-------SNESSQLDADVRATY 149 Saccharomyces c...
A0E3Z9        76 ERQYLDVt----eKVSYDFIIELKEgpqsIENFLFQFKWNDQTFPRAS-ALSELVKAI-------SSRATHVETDLRQKS 143 Paramecium tetr...
EGR27357      73 ERQYLDLt----eQQTADFKVETKNdvytLPNFVQTFKWDDATFSRSN-PLPELLKIL-------KTRMSTIENDIRQKT 140
Q7RCK7        79 EKIAKEYd----eNIELKIIYQRQHi--nIDQYIRRFSWDDAKYPRNR-SLIDTIDVI-------INNITKLSDEIQIKS 144 Plasmodium yoel...
EEA06592      85 ERMALDLd----pTMELRIIWQRSSy--tIKQYLCHFSWDHAKFPKER-SMHENLNAL-------LQGIQKLDTDLRSKS 150
XP_004356034  75 SKQLTDLvgs-kpGKEKGLSINGQN----IQQYLSKFQWDDAKFNPKS-SLQEIVDKI-------QSTVAKLDEDLRAKL 141
XP_001708227 154 ERVIYTGkekmgkHFDYTVFVTDQN------SRLRELFW--LDFTRERvLTSHTIESVfleydrcQEEFTRLNTKYTNLL 225
Q388J5        76 ITIMQEIcee-prDVVATLRFNQTQem-tPAAFVKGFQWSSAQFDSNE-SILGLVEKF-------ANYFATTEEGVRLVM 145 Trypanosoma brucei
Q4QDY6       109 IGLMEETsgk-prSVVTTFRINQTQem-sAAGYIKNFLWSTAQFDPKE-TIHNLIEKI-------SRINATADERVRVML 178 Leishmania major
XP_001012282  73 ERTYMDIt----eSQHAEFQVNTRSssvsLSQYVQDFKWDNNIFSRSQ-PLMELLKSF-------QQKATTIDNDIRQKQ 140 Tetrahymena the...
6O7W_O       150 ANYNSAKTNLAAAERK--------------------KTGDLSVRSLH-----DIVKPED-----FVlNSEHLTTVLVAVP 199 Saccharomyces c...
A0E3Z9       144 TSYQELKNQSQQVARK---------------------EGNLMVRDLVdvlkePIVKPRD-----FI-YSDYLTTLVAIVP 196 Paramecium tetr...
EGR27357     141 TAFQDAKNQSNVIAMK---------------------EGNLLVKDLGdvldsGKVKPKD-----FI-YNDSVTTVCVIVQ 193
Q7RCK7       145 NVLNDLKEKKKLYISKh-------------------DTNNFIHKNLNeiltpQIVSESD-----FM-ETEYITTVIAYVP 199 Plasmodium yoel...
EEA06592     151 SQFNEIKQAVLNNLGKdfnsnsniqssngsgsgvklTNGLLTTKDLIdvitpDVIDESD-----IL-FTEHISTVFVVVP 224
XP_004356034 142 TDYNSLTSSVVAEERK--------------------LLGNLQVRSLN-----ELITTEN-----NT-QSEYLTTAFIVIP 190
XP_001708227 226 AEYNKVDAEIKAFEKM--------------------NDVSLLSCSLAky--vNVQNLDD-----FF-TTDYLTCCLIVVP 277
Q388J5       146 TKYNETRNKLTTVTRK--------------------AQGNLSVKPIR-----ELVTMKNrshpfIV-DTELLTNLFVAVP 199 Trypanosoma brucei
Q4QDY6       179 AEYNETRNKLIAANRK--------------------GEGNLSIRPIR-----ELVALYHrdyqcFV-DTELLATVFVAVP 232 Leishmania major
XP_001012282 141 QVLQEAKNNLNSVALK---------------------EGNLLVKDLSdvfrkEYVKEKD-----FI-YTENLTTVVAIVP 193 Tetrahymena the...
6O7W_O       200 KSLKSDFEKSYETLS-------------K----N-------------VVPASASVI--AEDAE-YVLFNVHLFK------ 240 Saccharomyces c...
A0E3Z9       197 KTQIQEWLACYEFLC-------------E----N-------------VVPQSARQFq-IEDKDnLTIWRVVIVRqsfdkd 245 Paramecium tetr...
EGR27357     194 KQQIEKFQNAYETIH-------------H----C-------------VVPGSAKQFd-IEDRDgYTLWRVLVMKydykti 242
Q7RCK7       200 KDLINEWVNNYEKFS-------------Q----Y-------------VVPRSTKQFnnLIDKDgNTLWKVFVFK------ 243 Plasmodium yoel...
EEA06592     225 KGQHDSFLKYYERSD-------------P----Y-------------VVPKSAKFIpkIIDKEgNELVRVFLFQ------ 268
XP_004356034 191 QSMEKEFLATYENLS-------------DelskF-------------VLMRSAKKI--EQDND-YVLYGVCVFR------ 235
XP_001708227 278 KTGVNEFLAEYAALGcedadgakkkgrpDqptvTptlpldgdsavlgVVPGSARRL--KDDST-HALFSVILFK------ 348
Q388J5       200 LSSKREWLNEYWSLN-------------D----F-------------VCPDSNCII--AEDSE-FVLNSIVVFR------ 240 Trypanosoma brucei
Q4QDY6       233 VAAQKEWMATYWKMN-------------E----Y-------------VCPQSNRVV--AEDKE-YVLNSIVVFR------ 273 Leishmania major
XP_001012282 194 NNVLEHFQQQYELMH-------------H----C-------------VVPGSAKQFegIQDKD-YTVWRIVIFKldyknl 242 Tetrahymena the...
6O7W_O       241 --------------KN-----VQEFTTAAREK-KFIPR-EFNYSEELIDQLKKEHDSAASLEQSLRVQLVRLAKTAYVDV 299 Saccharomyces c...
A0E3Z9       246 hdievadkgdddkgKKqrqtpVEEFIQKARDKlRITVK-EFEYKSQESKEREKLRLDLKSKSDHMNTTLKQACEKAFSDL 324 Paramecium tetr...
EGR27357     243 qkqllnqsnqdkenNKrqktpVEEFMAAMRDQlKLTVR-EFEYKPTEYKEREKQRTELQVKTKSLSSVLKQTCEKSFGGL 321
Q7RCK7       244 --------------KF-----VNNFIENAKNK-NFIVK-PFKYDESHYNNIMESRTKIETEVIRQETFLRRMCLAAFSDV 302 Plasmodium yoel...
EEA06592     269 --------------SS-----MESFKQNCKSR-KFTVRdDFHYSQEKYRTLMENRKKLVQEKGKQEKYLKRMCFASFSDI 328
XP_004356034 236 --------------KF-----YDNFRIKCQER-KWVVR-DFKTET---ENKPQERSKLSEDQKNYKTSFIRWCRIQFPES 291
XP_001708227 349 --------------KD-----QQRCLDYFREK-KWIVR-EYIPEEADAGSEGRLATLTHVKADREKA-FQQHIESTLAAC 406
Q388J5       241 --------------RV-----LEDVKLACRKR-RYIVR-DSDAADEPSIRDLNDFIKRAESEKK---NFGLVLRQRYTGC 296 Trypanosoma brucei
Q4QDY6       274 --------------KI-----MDDLKTACRKK-RYVIR-EVEGTDDLSSAELRSLQQRAEKEKK---ALYTLLWQQYCTC 329 Leishmania major
XP_001012282 243 kkillegekldengKRqk-tpVEEFISASREKlKVTVK-EFQYNENDCAERERQRTAFQTQANSQSGKLRQTCEKSFGNL 320 Tetrahymena the...
6O7W_O       300 FINWFHIKALRVYVESVLRYGLPPHFNIKIIAVPP--KnLSKCKSELIDAFGFLG--GNAF---MkdkKgkinkqdtslh 372 Saccharomyces c...
A0E3Z9       325 YITYMHLKVLRLVVDIAMRFGAAEPNIQCILKPDQ--GkEKKVQQSLLKLFADPS----QVg--LygtKeele------- 389 Paramecium tetr...
EGR27357     322 YNTYIHLKYLRLVVDIATRFGIKNKFSTCLIEPSN--GkEKQIQVRLMKLFGDPQ----ELg--MygtKeele------- 386
Q7RCK7       303 FIAFIHINILRVFCESVLRFGVPPNFASFSIRI-NgeSkEKKVRKKLYDIFSTTD---------SigkNyakr------- 365 Plasmodium yoel...
EEA06592     329 FISWLHIKAMRCFVEAVLRYGVPPQFASFLIRMDVssSkFAKAKNVVETTFKKKGkiGTLYkssStdkEi---------- 398
XP_004356034 292 FVAWIHLKALRVFVESVLRFGIPMNFQAILMKPHK--KeDRKLRDVLLDQFKYLG---------SqhiSgkge------- 353
XP_001708227 407 LALAIDTSILELYIEAQLRFG--ADFQMLMFMSSG--VtRKGLKQIVNYSFNELLng----------------------- 459
Q388J5       297 YVAWVHLKAVRLFVESLLKYGLPPRCISIFLQVDK--RkEAEIRKKISQLYPDLSv---PFsntSsveDgslqyeypyvs 371 Trypanosoma brucei
Q4QDY6       330 YVAWIHLKAVRVFIEALLKFGLPPRFIAVVLQVPA--DkEAEIRKRIAQLYPDLTt---PLandMtvdTgal-------- 396 Leishmania major
XP_001012282 321 YEVYIHLKFLRLVVEIAAKFGQKSNNTTCLIQPAP--GkEKQVQQKLLKLFADRA----QLdagMygtKeele------- 387 Tetrahymena the...
6O7W_O       373 qyaslvDTE--------YEPFV 386 Saccharomyces cerevisiae S288C
A0E3Z9       390 -------------dtedFFPFV 398 Paramecium tetraurelia
EGR27357     387 -------------dtedFFPYI 395
Q7RCK7       366 --sdenDEE--------IYPYV 377 Plasmodium yoelii yoelii
EEA06592     399 ------DDD--------YTPYV 406
XP_004356034 354 ---edaSEK--------FFPYV 364
XP_001708227 460 -----cDQRvydvdveaENPYL 476
Q388J5       372 ikmtnlqrc------------- 380 Trypanosoma brucei
Q4QDY6       397 ---------------qqEYPYV 403 Leishmania major
XP_001012282 388 -------------dtedFFPYA 396 Tetrahymena thermophila SB210
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