Conserved Protein Domain Family
TAS2R

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pfam05296: TAS2R 
Taste receptor protein (TAS2R)
This family consists of several forms of eukaryotic taste receptor proteins (TAS2Rs). TAS2Rs are G protein-coupled receptors expressed in subsets of taste receptor cells of the tongue and palate epithelia in humans and mice, and are organized in the genome in clusters. The proteins are genetically linked to loci that influence bitter perception in mice and humans.
Statistics
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PSSM-Id: 283059
Aligned: 20 rows
Threshold Bit Score: 237.172
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9NYW2     1 MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYILTNLVIARICLISVMVVNGIVIVLNPDVYTKNK 80  human
Q9JKT2     1 MMEGHMLFFLLVVVVQFLTGVLANGLIVVVNAIDLIMWKKMAPLDLLLFCLATSRIILQLCILFAQLGLSCLVRHTLFAD 80  house mouse
Q9NYW7     1 MLESHLIIYFLLAVIQFLLGIFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYVNVIVIFFIEFIMCSA 80  human
Q9NYV9     1 MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIWEILVSWFLALHYLAIFVSGT 80  human
Q9JKT7     1 MGSSLYDILTIVMIAEFIFGNVTNGFIVLTNCIAWLSKRTLSFIGWIQLFLAISRVVLIWEMLLAWLKYMKYSFSYLAGT 80  Norway rat
EDM01676   1 MEPVIHVFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEMY-ACFKIVYGSSSFIFGM 79 
Q9NYW4     1 MLSAGLGLLMLVAVVEFLIGLIGNGSLVVWSFREWIRKFNWSSYNLIILGLAGCRFLLQWLIILDLSLFPL----FQSSR 76  human
Q9JKT3     1 MLWELYVFVFAASVFLNFVGIIANLFIIVIIIKTWVNSRRIASPDRILFSLAITRFLTLGLFLLNSVYIA--TNTGRSVY 78  house mouse
Q9NYW5     1 MLRLFYFSAIIASVILNFVGIIMNLFITVVNCKTWVKSHRISSSDRILFSLGITRFLMLGLFLVNTIYFV-SSNTERSVY 79  human
Q9JKE7     1 MLSTVSVFFMSIFVLLCFLGILANGFIVLMLSREWLWRGRLLPSDMILLSLGTSRFCQQCVGLVNSFYYSLHLVEYSRSL 80  Norway rat
Q9NYW2    81 QQIVIftfwTFANYLNMWITTCLNVFYFLKIASSSHPLFLWLKWKIDMVVHWILLGCFAISL--LVSLIAAIVLSCDYRF 158 human
Q9JKT2    81 NVTFV----YIINELSLWFATWLGVFYCAKIATIPHPLFLWLKMRISRLVPWLILASVVYVT--VTTFIHSRETSELPKQ 154 house mouse
Q9NYW7    81 NCAIL----LFINELELWLATWLGVFYCAKVASVRHPLFIWLKMRISKLVPWMILGSLLYVS--MICVFHSKYAGFMVPY 154 human
Q9NYV9    81 GLRIMifswIVSNHFNLWLATIFSIFYLLKIASFSSPAFLYLKWRVNKVILMILLGTLVFLFlnLIQINMHIKDWLD--- 157 human
Q9JKT7    81 ELRVMmltwVVSNHFSLWLATILSIFYLLKIASFSRPVFLYLKWRVKKVLLLILLGNLIFLMfnILQINTHIEDWMD--- 157 Norway rat
EDM01676  80 KLQILyfawILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPgiLMQRTLEERPY----- 154
Q9NYW4    77 WLRYLsifwVLVSQASLWFATFLSVFYCKKITTFDRPAYLWLKQRAYNLSLWCLLGYFIINLllTVQIGLTFYH------ 150 human
Q9JKT3    79 FSTFFllcwKFLDANSLWLVTILNSLYCVKITNFQHPVFLLLKRTISMKTTSLLLACLLISAltTLLYYMLSQISRFPEH 158 house mouse
Q9NYW5    80 LSAFFvlcfMFLDSSSVWFVTLLNILYCVKITNFQHSVFLLLKRNISPKIPRLLLACVLISAftTCLYITLSQASPFPEL 159 human
Q9JKE7    81 ARQLIslhmDFLNSATFWFGTWLSVLFCIKIANFSHPAFLWLKWRFPALVPWLLLGSILVSF--IVTLMFFWGNHTVYQA 158 Norway rat
Q9NYW2   159 HaiaKHKRNITeMFHVSKIPYFEPLTlf--nLFAIVPFIVSLISFFLLVRSLWRHTKQIKlYATGSRDPSTEVHVRAIKT 236 human
Q9JKT2   155 IfisFFSKNTT-RVRPAHATLLSVFV-----FGLTLPFLIFTVAVLLLLSSLWNHSRQMR-TMVGTREPSRHALVSAMLS 227 house mouse
Q9NYW7   155 FlrkFFSQNATiQKEDTLAIQIFSFV-----AEFSVPLLIFLFAVLLLIFSLGRHTRQMRnTVAGSRVPGRGAPISALLS 229 human
Q9NYV9   158 ----RYERNTTwNFSMSDFETFSVSVkftmtMFSLTPFTVAFISFLLLIFSLQKHLQKMQlNYKGHRDPRTKVHTNALKI 233 human
Q9JKT7   158 ----QYKRNITwDSRVNEFVGFSNLVllemiMFSVTPFTVALVSFILLIFSLWKHLQKMHlSSRGERDPSTKAHVNALRI 233 Norway rat
EDM01676 155 ----QYGGNTSeDSMETDFARFTELIlfnmtIFSVIPFSLALISFLLLIFSLWKHLQKMQlSSRGHGDPSTKAHRNALRI 230
Q9NYW4   151 ----PPQGNSSiRYPFESWQYLYAFQl---nSGSYLPLVVFLVSSGMLIVSLYTHHKKMKvHSAGRRDVRAKAHITALKS 223 human
Q9JKT3   159 I---IGRNDTSfDLSDGILTLVASLV-----LNSLLQFMLNVTFASLLIHSLRRHIQKMQrNRTSFWNPQTEAHMGAMRL 230 house mouse
Q9NYW5   160 V---TTRNNTSfNISEGILSLVVSLV-----LSSSLQFIINVTSASLLIHSLRRHIQKMQkNATGFWNPQTEAHVGAMKL 231 human
Q9JKE7   159 FlrrKFSGNTTfKEWNRRLEIDYFMPlk--lVTTSIPCSLFLVSILLLINSLRRHSQRMQhNAHSLQDPNTQAHSRALKS 236 Norway rat
Q9NYW2   237 MTSFIFFFFLYYISSILmTFSYLMTKYKLAVEFGEIAAILYPLGHSLILIVLNNKLRQTFVRMLTCRK 304 human
Q9JKT2   228 ILSFLILYLSHDMVAVL-ICTQGLHFGSRTFAFCLLVIGMYPSLHSIVLILGNPKLKRNAKTFIVHCK 294 house mouse
Q9NYW7   230 ILSFLILYFSHCMIKVF-LSSLKFHIRRFIFLFFILVIGIYPSGHSLILILGNPKLKQNAKKFLLHSK 296 human
Q9NYV9   234 VISFLLFYASFFLCVLIsWISE-LYQNTVIYMLCETIGVFSPSSHSFLLILGNAKLRQAFLLVAAKVW 300 human
Q9JKT7   234 MVSFLLLYATYFISFFIsLIPM-AHKKGLDLMFSLTVGLFYPSSHSFILILGHSNLRHSSCLVITYLR 300 Norway rat
EDM01676 231 MVSFLLLYTSYFLSLLIsWIAQ-KHHSKLVDIIGIITELMYPSVHSFILILGNSKLKQTSLWILSHLK 297
Q9NYW4   224 LGCFLLLHLVYIMASPFsITSKTYPPDLTSVFIWETLMAAYPSLHSLILIMGIPRVKQTCQKILWKTV 291 human
Q9JKT3   231 MICFLVLYIPYSIATLL-YLPSYMRKNLRAQAICMIITAAYPPGHSVLLIITHHKLKAKAKKIFCFYK 297 house mouse
Q9NYW5   232 MVYFLILYIPYSVATLVqYLPFYAGMDMGTKSICLIFATLYSPGHSVLIIITHPKLKTTAKKILCFKK 299 human
Q9JKE7   237 LISFLVLYALSYVSMVId-ATVVISSDNVWYWPWQIILYLCMSVHPFILITNNLKFRGTFRQLLLLAR 303 Norway rat
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