Conserved Protein Domain Family
DOR

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pfam14839: DOR 
DOR family
This family of proteins regulate autophagy and gene transcription.
Statistics
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PSSM-Id: 464343
Aligned: 12 rows
Threshold Bit Score: 179.648
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDV95623            122 EDFNEDEWYIVEKEEEEEDSLPrsdseeelsvvelqaksvgggaaaaagaasaparrrqhqqqhinshslysgprpqqqr 201
XP_002931577         24 SEKEDDEWILVDFIAQVDPGSR---------------------------------------------------------- 45 
XP_001506755         24 SEKEDDEWILVDFI-DNCTSFSse-------------------------------------------------------- 46 
Q9QXE4               24 SEKEDDEWILVDFI-DTCPGFSaeeee----------------------------------------------------- 49  house mouse
XP_003219559         24 SEKEEEEWIVVDFI-DTCNNFSmveeedeee------------------------------------------------- 53 
XP_015138407         24 SEKEDDEWILVDFIADTCTNCTteq------------------------------------------------------- 48 
XP_005986808         26 SEKEEDGWLIIDFPDNYASDLSaee------------------------------------------------------- 50 
EFA01105             39 AEAEDD-WVLVDRRSDDSEGNSkssslesl-------------------------------------------------- 67 
WGS:AAPU:GI12726-PB 122 DDIDEDEWYIVEKEDEENDSLPrsdseeeltvaraaagapaaapaaaarrrqhi---------------nshslysgprp 186
XP_015031039        118 DDFNEDEWYIVEKEDEEDDSLPrsdseeelsvskaapsgsaaaanaaattrrrqh--------------inshslysgpr 183
XP_015213022         28 EKEDDDEWILVDYL-DTCTNTCrege------------------------------------------------------ 52  spotted gar
XP_006012907         28 AEKEEEEWILVDYI-DNCTNCSgee------------------------------------------------------- 51  coelacanth
EDV95623            202 nylqrtraargtlssstrnvvAAAPAASENcddDSQSAAVSQSLyapmtisisrGATSSPSGSDssSSSSSSGSSSdSSs 281
XP_002931577         46 ---------------------VSEEAATFEvisHSDETSVLPHV----------SNTFERLGTT--SDSCFIHFNL-CP- 90 
XP_001506755         47 -------------------edTSEESSD-------DHPPVFSCL----------PASLECLTEA--SDSCFIQFES-CP- 86 
Q9QXE4               50 -----------------ededIGEESSA-------EHTSVFSCL----------PASLECLTDT--SDSCFLQFES-CP- 91  house mouse
XP_003219559         54 ------------eeeeedncnIHETSSV-------DHPPVFSHL----------PNSLECLSDA--SESCFIQFDS-CP- 100
XP_015138407         49 -------------------ddIAETSPA-------GSSPVFTCL----------PSPLEHLPEA--GESCFIQFES-CP- 88 
XP_005986808         51 -------------------qvVMEGFASSCy--PSNKPP--SPA----------ASSLEYLSDC---NSGPLLPQP-CG- 92 
EFA01105             68 ----------------nleqeddDDDGLIVverSPDRVVVVNTGslpvpalltrTNSVPRVTTTt--------------- 116
WGS:AAPU:GI12726-PB 187 qqqrnylqrtraagrtlsistLSPPRTVPAnelGSDTSAVSQSLyap-----vaAAAVSPSGSDs-SSSSGSSGAG-LL- 258
XP_015031039        184 pqqqrnhlqrtraartlsistLSPPRSVPD---SD--NAVSQSLyapv---vvaSAAISPSGSEssGGS--------GGs 247
XP_015213022         53 -----------------svicAQEDSSL-------DSPALFSSI-----------SSLASTREL--VDTGFLELNP-CT- 93  spotted gar
XP_006012907         52 ------------------adtNKPEKPT-------DYVAVFSSS----------DSSLDLLVET--SDSCCLQFDS-CP- 92  coelacanth
EDV95623            282 gkgcgsagvmMEESWYVTPPPCFTSIG--PINMETSPFENLLIEHPSMSVY--------HSIRSSqagtesfvnldlgaA 351
XP_002931577         91 ----------MEESWFVTPPPCFTAGEltSMAVKTSPMENLLIEHPSMSVYavhnmchkPETSCE--------------S 146
XP_001506755         87 ----------MEESWFITPPPCFTAGGltTIKVETSPMENLLIEHPSMSVYavhgscrsLNETNCaa------------e 144
Q9QXE4               92 ----------MEESWFITPPPCFTAGGltTIKVETSPMENLLIEHPSMSVYavhnscpgLSEASCgn------------d 149 house mouse
XP_003219559        101 ----------MEESWFITPPPCFTAGGlaTLKVETSPLENLLIEHPSMSVYavhnthhsLNKTSCgdeeee--eedeeeK 168
XP_015138407         89 ----------MEESWFITPPPCFTAGGltAIKVETSPMENLLIEHPSMSVYavhnachsLSDTGCgd------------e 146
XP_005986808         93 ----------MEESWFVTPPPCFTAECegPVKVESSPMENLLIEHPSMSVYsssnpgnnSTMEEI--------------- 147
EFA01105            117 ---------sMEESWFLTPPPCFISTG--PVHMETSPLENLLIEHPSMSVYthhgrrynHFEEVEaepeevevvvaveeA 185
WGS:AAPU:GI12726-PB 259 ----------MEESWYVTPPPCFTSIG--PINMEASPFENLLIEHPSMSVY--------HSIRSSqagtesfvnldlgsA 318
XP_015031039        248 gkgl-gsgvlMEESWYVTPPPCFTSIG--PINMEASPFENLLIEHPSMSVY--------HSIRSSlagtesfvnldlgsA 316
XP_015213022         94 ----------LEESWFITPPPCFTAGGqaPGLLETSPMENLLIEHPSMSVYavhnlhntLKDTARrsr----------dq 153 spotted gar
XP_006012907         93 ----------LEESWFITPPPCFTAVGhaAVQVETSPMENLLIEHPSMSVYavhnlrrsLKETSSrs------------a 150 coelacanth
EDV95623            352 ELQQPEpqlepeqapvpaPVQGQVQAqTVLRQPSSNSARFdRHAALQLKQ-QTLAREGQKSNNKKQHQQlCRSAIKRANK 430
XP_002931577        147 GFPSPD------------RTELATENkKKGKHIHCSIAAL-AARMKGLEN-TKIYLGDKLTKLHLEKHP-SRKGFRRQNL 211
XP_001506755        145 EFHNSS------------SPRMEAQN-EMEQHIHCYVTAL-ATQTTFLEQ-TKSLRPTPWVKKHSGRHSlTRNSLRRQNL 209
Q9QXE4              150 EY-NSS------------GPRMEAQS-EMGKHIHCCVAAL-AAQATFLEQ-PKSFRPSQWIKGHSERQSlNRNGLRRQNL 213 house mouse
XP_003219559        169 ENRNAT------------NPQSEAQS-QMGQHIRCYIATL-ATHSTFLEQ-TKNLRPSQWTKEHHERQYlTRNCLRRQNL 233
XP_015138407        147 EFCGPG------------SPRLEARN-ETGQRVHCFVAAL-PTRSSVLEK-NKSFRPTHWIKEHGERHYpSRNGLRRQNL 211
XP_005986808        148 ------------------TLETLPQI-QVERRTATHPTAI-TSQARTLEK-VSHIRHIQRAKLRVEKHWlTKSHFQRQNL 206
EFA01105            186 GDSDDEgavlvhraprvnRVHVLQQQ----------------------ERqGVKSKHAQKIQIQKSCKFvTRSTLDRTNK 243
WGS:AAPU:GI12726-PB 319 SVPEPEpepaq---paaaV-----------QQPRSHSARFdRHAAAELKQ-QTLARQSQKSHNKKQHQQlCRSAIKRANK 383
XP_015031039        317 ELPQPEpepepapapvaaVVQQQQQ-----QAPRNHNAYFdRHAAEKLKQ-QTLARQSQKSLGKQQHQQlCRSAMKRANK 390
XP_015213022        154 SF-N----------------RMEPQN-RTGQHIGCYAAAL-SAHTGLFEQ-AKYVRLSQRTKDNAEKQHlSRSTLRRHNL 213 spotted gar
XP_006012907        151 GFEKPD------------VS-KAAQN-NMDQNIRCYAAAL-TGHSTHLKQ-TKSVQLAQKEKGHFEKHLlNRNSLRRQNL 214 coelacanth
EDV95623            431 VRDfqakaHRPRRSEMQHcKLVSGANNN 458
XP_002931577        212 IRG-----CRSQQTKHSR-LLVHQPSPR 233
XP_001506755        210 TRD-----CHSRQTKHSG-LIVHQPCQR 231
Q9QXE4              214 TRD-----CHTRQMKHSG-WVVHQPCPR 235 house mouse
XP_003219559        234 TRD-----CYSRQLKNNG-ILVHQPCQR 255
XP_015138407        212 TRD-----CHSRHIKHNG-LFVHQPCQR 233
XP_005986808        207 ARE-----CRPRRAKHQG-SFVYQPCQR 228
EFA01105            244 AREvnsrnRRQRRGERSQgAKRSYANNN 271
WGS:AAPU:GI12726-PB 384 VRDfqakgQRPRRSDMQHcKLVSGANNN 411
XP_015031039        391 VRDfqakgQRPRRSDMQHcKLLSGANNN 418
XP_015213022        214 VRD-----GGSRQVKSSA-VFVHQPTQR 235 spotted gar
XP_006012907        215 ARD-----CQSRQTKPNG-FLVHQPCQR 236 coelacanth
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