Conserved Protein Domain Family
TFP_LU_ECD_Ly6G5b
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cd23544: TFP_LU_ECD_Ly6G5b 
extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G5b (Ly6G5b) and similar proteins
Ly6G5b is a glycosylated, potentially secreted protein which could act as ligand for other cell-surface receptors and could thus potentially have a role in cell signaling. It contains an extracellular domain (ECD) which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).
Links
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Statistics
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PSSM-Id: 467074
Aligned: 11 rows
Threshold Bit Score: 86.6879
Created: 28-Nov-2018
Updated: 27-Apr-2023
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8NDX9        25 IRTCHfCLVEDPsvGCISGSEKCTISssSLCMVITIYYDv----KVRFIVRGCGQYisyrCQEKRntyfaEYWYQAQCC- 99  human
Q8K1T4        25 VRTCHlCLLEDPslGCISGSEKCTISlpSPCMVITIYKNt----TVRFHVRGCGQHhsyrCQERHviyqsDYLYKADCC- 99  house mouse
NP_001001934  25 VRTCHlCFLEDPsiGCISGSEKCTISssSPCMVITIYQNv----KVRFHVRGCGQHhsfrCQENHviyysDYWYRVNCC- 99  Norway rat
NP_001179131  25 VRTCHlCLLENPavGCISGSEKCTISssSPCMVISINYEn----KARFLIRGCGQHnsyrCQEKLptyisEYWYSAQCC- 99  cattle
XP_027732545  25 ARFCHlCLLEDPflGCLTGSDMCIPDnkGQCMVINIYNGs----KLTYVVRGCGEHssfrCKEVQngfilYYWFRAECC- 99  common wombat
XP_028911410  20 ALRCKhCLLEVPnqGCLDGSNFCNAEmgRACMTISIHREn----ELQYLVRGCGRQsgfhCGEIRvlkvtGYWYRAQCC- 94  platypus
XP_008174060  21 NLRCRqCALNEPyiGCLPGVSECTPKagHPCMTVNIGYRg----EVQFLLQGCIMNps-rCGMVKelmvpEYHINITCCs 95  western painted...
XP_028569578  20 SIKCNtCLMKSPdaECMTGVEGCMSQg-EKCMTIRISQDg----KEKFRILGCTRQkkkgCGVNKes--hGHQVSIRCC- 91  Common wall lizard
XP_020670870  50 SLYCKeCLVETDdgRCLITAGTCKAA--ETCMTIMIYAEk----EVKFRVYGCFVSdhyhCGMRKkt--gGHTLNVRCCa 121 central bearded...
XP_007658496  20 AVRCHhCLEFKDg-KCILGPGDCRPKagESCVTQKIVTFgagikNYEKFVTGCVKN----CRERRfpvwpNQQAHIRCCk 94  platypus
XP_027296606  46 TRHCW-CLLEDPsmGFISGXEKCTVSssSPRVVITVYHSv----QIHFHVGSCGQYnsycCKEKHkspvsQYWCKADXC- 119 Chinese hamster

Q8NDX9       100 QYDYCNS 106 human
Q8K1T4       100 QYDYCNS 106 house mouse
NP_001001934 100 QYDYCNS 106 Norway rat
NP_001179131 100 QYDYCNS 106 cattle
XP_027732545 100 QYDYCNA 106 common wombat
XP_028911410  95 RHDYCNS 101 platypus
XP_008174060  96 HASFCNE 102 western painted turtle
XP_028569578  92 SSDYCNV 98  Common wall lizard
XP_020670870 122 GRHLCNK 128 central bearded dragon
XP_007658496  95 NRDFCND 101 platypus
XP_027296606 120 QDDYCNS 126 Chinese hamster
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