Conserved Protein Domain Family
SelK_SelG

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pfam10961: SelK_SelG 
Selenoprotein SelK_SelG
This entry inclues a group of eukaryotic selenoproteins, such as SelK and SelG. SelK seems to play an important role in protecting cells from endoplasmic reticulum stress induced apoptosis. SelG may be involved in regulating the redox state of the cell.
Statistics
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PSSM-Id: 463198
Aligned: 36 rows
Threshold Bit Score: 53.0694
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_006631112   2 VYVS-NGQVLDSRsqsPWRLSFISDLFWGAVEFIGLFFQTIFQPDLSKKGn-SGSSSYSRf-------------DDGRGP 66 
3_pfamImport   1 VYIGrDGKVYDKQ---PYNLDWFLGLFIGFWNFLCFF--SLLAPLFPDSS--SGSGNNRRw------------gGGGGGS 61 
XP_002070902   2 VYIDrNGRVWEKR---PWDWQRIVEIFFGLWYMIVQFFQTLVAPFNGNGNgnNDNQRRSNwggg-------wggGGGGGG 71 
XP_001967374   2 VYIDhNGRVWEKR---PWDWRRVVELFFGIWFAIKQLFASFLAPFNSNDn--SNSQRRNNwdrwg----gggggGGGGGG 72 
Q7Z2C4         2 VYIDhNGRVWEKR---PWDWRRIVELFVGIWFAIKQLFLTFLAPFTGNNn--QANPRRGNgwggg----ggwggGGGGGG 72  fruit fly
KMZ09375       2 AYVDqYGRLWEKR---PWDLKRVLDIFVGIWFAVKQLFASFLSPFTGNDSn-GDNFRRGNgwgssswgggggggGGGGGG 77 
O62437         2 VYIDkDGNVLEKK------QKGIVEMIVGFFTFIMLFFRSLLGFTSPTNRn-SNSQDYRNivrgg-----gvngAGGGGN 69  Caenorhabditis ...
Q179T4         2 VYIArDGSVHETQ---PWSVQRFIGMITGFLGLIAMFFKTMFNMDSNQPSrgQDSSGIHWr------------gGGGGGP 66  yellow fever mo...
ETN67798       2 VYIGrDGVVRASQ---PWGIERIKGIIRGFFNFLLMFFRTMLDFNLGAGSgaGNQRGSgs-------------gGGGDGP 65 
XP_001845376   2 VYVArDGTVHQSQ---PWGVQRLLGLITGFFNFFVMFFKTLFGDLKPSGSgdAASSGSSRrg----------ggGGGGPP 68 
XP_006631112  67 pgf-pggRRRMGRvnhmGGGPSAPPTGGG 94 
3_pfamImport  62 -----------------TGGGGGPGKPGG 73 
XP_002070902  72 -----------------GGGGGGSGGGGG 83 
XP_001967374  73 -----------------GGGGGYAGGNGG 84 
Q7Z2C4        73 -----------------GGGGGRPGSGSG 84  fruit fly
KMZ09375      78 -----------------GGGGGGGGGGGG 89 
O62437        70 -----------------AYRRNGGGGGGG 81  Caenorhabditis elegans
Q179T4        67 pppggprRRPIGR----VMTLSDCTVPGG 91  yellow fever mosquito
ETN67798      66 pr----pPRRIGR----TMTLSDCTVPGG 86 
XP_001845376  69 gppggprQRPIGR----MMTLRDCTIPGG 93 
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