5I3E


Conserved Protein Domain Family
DNase_II

?
pfam03265: DNase_II 
Deoxyribonuclease II
Statistics
?
PSSM-Id: 460868
Aligned: 78 rows
Threshold Bit Score: 126.616
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
5I3E_A         12 SPRDEQ---------------NRSVDLWFAYKVP--KltkDADSDSASGYEYVYYdrq-vgaVQKSPNLMND-------- 65  
XP_004359946   44 TCKSPT---------------GDSVQWWFIKKLP-------------YSNQYIYIdnd-sktIQF-QNDLSD-------- 85  
EFA79444      986 SCLSPS---------------GAAVSWWFARKLP-------------QSSSYLYFdsq-ssvVQY-FDSINS-------- 1027
EFA77037     2658 SCLSTQ---------------GASVSWWFVRKIP-------------QSQSYIYVdsd-sqdMKY-LPSINS-------- 2699
Q55D38         24 KCITTKniykdgqvfgdgvtiEKNVEWWFLEQLG-------------HSKGSIYTdn----tLKGGSSEINEianynird 86   Dictyostelium...
Q55D42         24 KCITTKnvytksq-vfidkdgEKNVEWWVLEQLS-------------QSQGAIYTdn----eLNGANPVINElayynirn 85   Dictyostelium...
Q22N06         83 QCLNQQ---------------GKKVDWFIALKLP-------------SGAEYAYCdsencqtLKIQSQPLDD-------- 126  Tetrahymena t...
EFA81407       22 TCVNPE---------------GKAVKWWIHLADAdsA---TEENMYARGLYYDSL-------LDLMKKHVDQ-------- 68  
XP_976863      24 QCLDQN---------------NQPVDWFIALKFP-------------NGTNYAYCdsndcskLAVQTKKLDD-------- 67   Tetrahymena t...
XP_001010838   21 SCINPN---------------GAQVDWFITLKLN-------------NGDDYAYCdskscdkIQLSGFKIND-------- 64   Tetrahymena t...
5I3E_A         66 -PKGAl-FYTLDSVFg-----------------dPGDTTGWILYNDE--------------MPADAnr---------sNN 103 
XP_004359946   86 -DQSSl-ARTLSQLSqqqqqqqlnggggggsdqnDNSDYYYYFYNNEfqnlnsndrtnfplPADKSti---------qPS 154 
EFA79444     1028 -NSSSl-ALTLNQIKsn----------------nVQTTNGYLAYNDM--------------PWLDDlsgklaqsltgdVN 1075
EFA77037     2700 -TTGCl-ARTLNQIAis----------------sSESSNGYVVYNDH--------------PWFDDlsgqlslsingyGN 2747
Q55D38         87 pKEPNpiTSTYKQSLpn---------------esKKIIYNSLTYNDQ--------------ISGGS-------------- 123  Dictyostelium...
Q55D42         86 pDEPNpiTSTYIQSYpn---------------ksGKTIYNSLTYNDQ--------------PSNSG-------------- 122  Dictyostelium...
Q22N06        127 -VDSSplLKTLKQIEq-----------------vKSEEYSTLFWNDQ--------------PPTQS------------AS 162  Tetrahymena t...
EFA81407       69 -ANGD--KITEQQCI-------------------DKNYLGLEWYHDQ--------------GYEHRvi--------dnSV 104 
XP_976863      68 -LSASplFNTLKQVQd-----------------iTSDEYATVFWNDE--------------PPTFD------------VS 103  Tetrahymena t...
XP_001010838   65 -AKNSpiLRTLQQIKqn----------------lNNDKQGYLLWNDQ--------------PPNNMt-----------AT 102  Tetrahymena t...
5I3E_A        104 ATLGHTKGVIAf-------DiaSS--SALWLLHSWPKy-------------AS---------------PSVPGV----P- 141 
XP_004359946  155 TVYSSSKGIVIlnkpplqnNntNKtfSGAYIVHSLSRfpqltttttnsfktPIt-----------------------hPn 211 
EFA79444     1076 KYNSLGKGILVsqs---kfNisYA--PGFHIKHSLEGfpvplgs-tgaiktPSs-----------------------yPd 1126
EFA77037     2748 LNKSLGKGIFVant---ffNatYS--PGFHIKHSMEGfpvplp--nglfktPSs-----------------------hPs 2797
Q55D38        124 -DSAHAKGFFIw-------N--EE--GGIHVIHSVPKs-----------------------------pETGYE-----Pl 157  Dictyostelium...
Q55D42        123 -NSAHAKGFFIw-------N--EE--GGIHVIHSVPNs-----------------------------pETGYK-----Pl 156  Dictyostelium...
Q22N06        163 STYAHAKGVMGi-------G--SE--QGFLIVHSTPKfpei------------------------qngKIVLGI----K- 202  Tetrahymena t...
EFA81407      105 FYHGHVKSLYVfdl--rdnDidSN--TGFFVSHSMRMpelkstg-sglyekAKwystittcilihtqlPKKYCMenegPf 179 
XP_976863     104 TTYAHAKGFIGt-------G--KE--NGFLVVHSTPKfpli------------------------kngKIQLSI----K- 143  Tetrahymena t...
XP_001010838  103 SSNAHAKGFISl-------G--QK--SGFILIHSVPEfpaf------------------------adsSSLKEIllniE- 146  Tetrahymena t...
5I3E_A        142 ---------------TP--LYGQTFLCLSLDLA-TAGKLaaqmaLHQQPQ----------------------VY------ 175 
XP_004359946  212 gtwfptdyylsplspSPssSYGHSLVCTSFK---DYEDVry-qiQSIYPY----------------------IYmt---n 262 
EFA79444     1127 gtwfpnd-yhlrpteSPdlSFGHSFLCHSFV---DATEIin-aiVAMKPF----------------------TYas---n 1176
EFA77037     2798 swipnd--yhliqnqGDdySLGHSFMCHSLI---DSSDFvn-giQSLKPF----------------------IYss---n 2846
Q55D38        158 fny---------dkdTLnnQHAQHSICITLSKE-ELHIIpk-yiIYSNLNiqtintvstglgkkakkvssanLYse---n 223  Dictyostelium...
Q55D42        157 fnf---------kenTLksQHAQHSICITLSKE-ELHIIpk-yiIYGNLNiqtintvspgs-gakrvssamfLYsq---v 221  Dictyostelium...
Q22N06        203 ---------------SNqqIYGQHYFCISTTNP-QLDKIas-ayNVDYPF----------------------VYdg---f 240  Tetrahymena t...
EFA81407      180 tlgsfttfsfsadkeNDkkNYKTLSKCFALNYGkKIQNI-----KFENDF----------------------TFenkdnp 232 
XP_976863     144 ---------------SNqtIYGQHYFCISTQSY-SLDQIaa-ayNVDWPY----------------------VYdg---h 181  Tetrahymena t...
XP_001010838  147 ---------------ESqqKYGQHFLCTSTSLE-NLEKLac-gyNIDNPK----------------------VYss---f 184  Tetrahymena t...
5I3E_A        176 LPRTggLD-HTSP-LYAltqp---------------------------lnasAPGDS-DSld---fkTRGGV----PFKV 218 
XP_004359946  263 LNLP--FK---DPlLKStfnslfyptyppkslylkpdaiklqslssrddngdRDPNSsISitssikwGGASIwhssNTIN 337 
EFA79444     1177 RFTA--NSnMFTPmFQ---------------------------------------------------STAAVippfRSSS 1203
EFA77037     2847 RFTP--TS--TTNiFSSl-------------------------------------------------FTDSTtnsfTSKD 2873
Q55D38        224 LHTE--VE-KISPgVINldvienla--------------------keipktfK--------------KLDGLm--sDYIL 264  Dictyostelium...
Q55D42        222 LKEE--VD-KKKTgVIDldvidskil------------------atkipktfK--------------ELDGLm--sEYIF 264  Dictyostelium...
Q22N06        241 VSKM--H--SQFPyFTRmlk-----------------------------nirDVEKDqDTvn---fkTLKGV----SMIK 280  Tetrahymena t...
EFA81407      233 IKVD--ML-STTHcLSN-----------------------------------DVPKDdSI-------CYDAK----TVCS 263 
XP_976863     182 VPPS--F--SDFPfLQRmlnnyr------------------------------dfttfNAvs---fiTLEGV----SMTK 220  Tetrahymena t...
XP_001010838  185 LPYY--IDqSSYPcLNQmkn-----------------------------nkrNTKTKqMIit---ysTLNGE----TFTK 226  Tetrahymena t...
5I3E_A        219 IAKnrkWGKDFWNdLVGPTLKADMYVETWIRGkippvLDSD----G---VHKTYD--------IKFIdlrKLGAPWA--- 280 
XP_004359946  338 YIS------------IPSKYKNPLPTNNGKNStm-vsSP----------ITHVINsqklpgdlVTRY---RIDSDKSq-- 389 
EFA79444     1204 WLT--------NTaFLSSAFQQDIFTPVGLSPll-itMPANfklpI---AATAITetklpsdfVSQH---NIPMQISq-- 1266
EFA77037     2874 WSK---------GyFISAGFRNDIFTPTRIQPls-itLPSKfkipS---GANAITdvklptefIIQN---NIPTKISq-- 2935
Q55D38        265 VKKkndGDPDIWNgII--------YLNKWSQLak-liLNEDitssDltlKPKETN--------VHYN---KIYESK---- 320  Dictyostelium...
Q55D42        265 DNKkndGDPDIWNgVI--------YLNKWSQLad-liLNKDitssDtnlKPKETN--------VHYY---KINES----- 319  Dictyostelium...
Q22N06        281 FSKsgkWAVPFYDkVAATNLKTNLFVESWGSPqeepe--------csqgSFSVYS--------NLYI---DFQQSGIq-- 339  Tetrahymena t...
EFA81407      264 FTD---FGMDPYL-LVAQHYDSHFFVSTDQET-----FPSLi--gS---TFSVRN--------IVTW---SPIWSREkkd 318 
XP_976863     221 FAKsgkWLVPFYDnLPAALLEVGLVVESWRFD-----EGSDcd-----qEFVVTN--------NLMV---SIPGAVT--- 276  Tetrahymena t...
XP_001010838  227 FSKnkdNQIPLYEqIVTQELKTGLLVQSWGRPyeea---------scsgSYQVVS--------NTRV---QIDGAPQ--- 283  Tetrahymena t...
5I3E_A        281 --WPETQ-DHAKWGITTTDN--WVCVGDINRMVTQEKRGGGTIAFQDPKLW-------------KA 328 
XP_004359946  390 --WDTSV-DKGIFGVSTIQS--LSCIGDYDQN-INSANGELMICINNSILS-------------SL 436 
EFA79444     1267 --WRASR-DHSHIGFNDT----HLCLGDYSAK--TTIGGGMAVCIKQTVLS-------------DF 1310
EFA77037     2936 --WKSDI-DKSYIAFNDT----HLCLGDYSSK--TSFGGGIAVCVINQFSS-------------EF 2979
Q55D38        321 --------NKGDYFIQTTN---KNLYKKYNEKIEETHKEK----IKFFIIWhyidn----fkngNN 367  Dictyostelium discoideum AX4
Q55D42        320 --------DKGRYFIQTTN---INLYKEYSEKNKEAHKDG----IKFFIVWhfidsskndlpngNN 370  Dictyostelium discoideum AX4
Q22N06        340 --YKWTK-DHSKYAISSDSSkpYVCLGDINRQTSQWKRGGGTVCFQNQQVY-------------NN 389  Tetrahymena thermophila SB210
EFA81407      319 geNSESRsRHEKLMVSKSKN--IICLGDSNRNDYSVHHAGTIFCIENEILA-------------KR 369 
XP_976863     277 --FKETV-DHSKYAISLDDDkpYVCLGDINRAKTQWKRGGGTVCFSNYDVH-------------RN 326  Tetrahymena thermophila SB210
XP_001010838  284 --FKDTQ-DHSKYGISIDKAkpFVCLGDINRMKSQWKRGGGTICISNKNIH-------------FQ 333  Tetrahymena thermophila SB210
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap